Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 118579151

GI number: 118579151

Start: 742480

End: 743532

Strand: Reverse

Name: trpD

Synonym: Ppro_0712

Alternate gene names: 118579151

Gene position: 743532-742480 (Counterclockwise)

Preceding gene: 118579152

Following gene: 118579150

Centisome position: 18.55

GC content: 60.68

Gene sequence:

>1053_bases
ATGATAAAAAAAGCCATTGCGCGCATTGTCGAACAGAAGGATCTGACGGAGGGGGAGATGATCGAGGTCATGGGACAGAT
CATGACCGGTGAAGCCACCCCGGCGCAGATCGGCGCCTTTATCACCGCCCTGCGCATGAAAGGCGAGACAATCGATGAGA
TCACCGGCGCCGCCAGGGTCATGAGGGAGCACGCCACACGCATCCGCGCCGGTAAGGACCTGCTGGATATCGATCGCGAC
GACATCAATATCGACCGGGAAACCATACTGGACGTGGTGGGAACCGGAGGGGACGGAACCAATACATTCAACGTTTCCAC
CACTGTGGCCTTCGTTGTTTCCGCCTGCGGCGTGAAGGTAGCCAAGCACGGTAACCGCTCAGTCTCCTCCCTGTGCGGCA
GTGCTGACGTGCTGGAAAAGTTGGGAGTCAACCTGGATATTACGCCGGAAACCGTCGAACAGTGCATCACCAAAATCGGC
ATCGGCTTCCTCTTCGCCCCGGCCTTGCACGGAGCCATGCGTTATGCCATCGGCCCCCGCCGCGAGATCGGCATCCGTAC
GATATTCAACATCCTGGGCCCCCTGACCAATCCGGCAGGCGCCGATTGCCAGGTCATGGGTGTCTACCGTCCCGGCCTGG
TGGAAAAACTGGCCGGCGTGCTGCACAGGCTCGGCTGCCGGCACGGTTTCGTGGTACACGGCATGGACGGCATGGATGAA
ATCACCACCACGACCGAGACCCTGATTGCCGAGGTAACCACCAGCGGCGTCAGTATATGCACCATACACCCGGAGGAACT
GGGTTTTAGCCGCTGTTCGATGGATGAGTTGCGCGGTGGAGACGCGACAGCCAACGCGGACATCGTCAGATCCGTCCTGC
AGGGCGTTGCCGGCCCCCGGCGTGATATCGTCCTGATCAACGCCGCCTATGCGCTGGTTGCCGCCGACAGGGCGGCAACT
CCAGAGCAGGCCATCGCCCTGGCTGCCGAGGCCATCGACAGCGGCCGGGCCATGGAGCAGCTGAGGAAATTGATCCAGAT
AACGAAGGACTGA

Upstream 100 bases:

>100_bases
TTTTTAGCCGTTATGCGGGACACGAGACCGGCATTGGCGGAGAGAATGCGGCATCGGTTTTTCGAAATCCGACCGACCCA
CACGGATTGAAGAGGCAGAG

Downstream 100 bases:

>100_bases
GCAGCAACTGGGGATATGAGCATGAACAACACACCGGACACATTGAAAAAGATCGTTGCCCACAAGTACGAGGAACTGCG
GGACCTCAAGGCGCACACTG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARVMREHATRIRAGKDLLDIDRD
DINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKVAKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIG
IGFLFAPALHGAMRYAIGPRREIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDE
ITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPRRDIVLINAAYALVAADRAAT
PEQAIALAAEAIDSGRAMEQLRKLIQITKD

Sequences:

>Translated_350_residues
MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARVMREHATRIRAGKDLLDIDRD
DINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKVAKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIG
IGFLFAPALHGAMRYAIGPRREIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDE
ITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPRRDIVLINAAYALVAADRAAT
PEQAIALAAEAIDSGRAMEQLRKLIQITKD
>Mature_350_residues
MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARVMREHATRIRAGKDLLDIDRD
DINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKVAKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIG
IGFLFAPALHGAMRYAIGPRREIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDE
ITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPRRDIVLINAAYALVAADRAAT
PEQAIALAAEAIDSGRAMEQLRKLIQITKD

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=294, Percent_Identity=37.0748299319728, Blast_Score=198, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320561, Length=329, Percent_Identity=30.6990881458967, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PELPD (A1ALX3)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900401.1
- ProteinModelPortal:   A1ALX3
- SMR:   A1ALX3
- STRING:   A1ALX3
- GeneID:   4571511
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0712
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   A1ALX3
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37249; Mature: 37249

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MREHATRIRAGKDLLDIDRDDINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKV
HHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
AKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIGIGFLFAPALHGAMRYAIGPR
HHCCCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCHH
ITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPR
HHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCC
RDIVLINAAYALVAADRAATPEQAIALAAEAIDSGRAMEQLRKLIQITKD
CCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKKAIARIVEQKDLTEGEMIEVMGQIMTGEATPAQIGAFITALRMKGETIDEITGAARV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MREHATRIRAGKDLLDIDRDDINIDRETILDVVGTGGDGTNTFNVSTTVAFVVSACGVKV
HHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHH
AKHGNRSVSSLCGSADVLEKLGVNLDITPETVEQCITKIGIGFLFAPALHGAMRYAIGPR
HHCCCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REIGIRTIFNILGPLTNPAGADCQVMGVYRPGLVEKLAGVLHRLGCRHGFVVHGMDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEECCCCCHH
ITTTTETLIAEVTTSGVSICTIHPEELGFSRCSMDELRGGDATANADIVRSVLQGVAGPR
HHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCC
RDIVLINAAYALVAADRAATPEQAIALAAEAIDSGRAMEQLRKLIQITKD
CCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA