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The map label for this gene is trpC [H]

Identifier: 118579150

GI number: 118579150

Start: 741655

End: 742458

Strand: Reverse

Name: trpC [H]

Synonym: Ppro_0711

Alternate gene names: 118579150

Gene position: 742458-741655 (Counterclockwise)

Preceding gene: 118579151

Following gene: 118579147

Centisome position: 18.52

GC content: 60.32

Gene sequence:

>804_bases
ATGAACAACACACCGGACACATTGAAAAAGATCGTTGCCCACAAGTACGAGGAACTGCGGGACCTCAAGGCGCACACTGC
TCTGGGCGAACTCCGTGTACGGGCCAGGGACATGGCGCCGACACACGGATTCGAGGCAGCCCTGCGGCGCAAGAAAGGGC
AAGGGCAGACCGCAATAATCGCCGAAGTAAAAAAGGGCTCGCCCAGCAGGGGGCTGATCAGGGCCGATTTCGACCCGCTG
GAGATCGCGCGCATCTACGAGACAAACGGAGCCACCTGCCTGTCCGTTCTGACTGACCAGCATTTTTTCATGGGCCGTCT
GGAGAATCTAACCAGGATCCGTGGCGAGGTCGACCTGCCACTCCTACGCAAGGATTTCATTCTGGACCCCTTCCAGATAT
ACGAGGCCCGCTGCGCCGGGGCAGACGCTATCCTGCTGATCACCGCTATCCTCGAACTGCCCCAGATGATCGACTACATT
ACACTGGCACGGGATCTGTCATTGGACATCCTGCTGGAGGTCCATGACGAGCGAGAGTTGGATGTCGCCCTACGCACCGA
CTGCACCCTGATCGGCGTCAACAACCGTAATCTGCGCACGTTCACGACTGATCTTGCCACCACCGGACGCCTTGCCAGCA
TGCTGCCGCCAGAACACCTGCTGGTGGCGGAGAGCGGCATTTCCACCCGGGCGGACATTGAGCGCCTCGCGGCCGATGGC
GCCGACGCCTTCCTGATCGGCGAGTCACTGATGCGCGAGACGGACATCGGCTCCCAGTTGCGCATACTGCTGGGCAACCG
TTAG

Upstream 100 bases:

>100_bases
CGCCCTGGCTGCCGAGGCCATCGACAGCGGCCGGGCCATGGAGCAGCTGAGGAAATTGATCCAGATAACGAAGGACTGAG
CAGCAACTGGGGATATGAGC

Downstream 100 bases:

>100_bases
CCAATGACCATCAGGCAGGAGAGCTACTTTTTGACATCTATTCCGTAGCTCTTTATTTTCCTGTGCAGGTTGCTCCGCTT
CAATTCGATGGTCTCGGCGG

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNNTPDTLKKIVAHKYEELRDLKAHTALGELRVRARDMAPTHGFEAALRRKKGQGQTAIIAEVKKGSPSRGLIRADFDPL
EIARIYETNGATCLSVLTDQHFFMGRLENLTRIRGEVDLPLLRKDFILDPFQIYEARCAGADAILLITAILELPQMIDYI
TLARDLSLDILLEVHDERELDVALRTDCTLIGVNNRNLRTFTTDLATTGRLASMLPPEHLLVAESGISTRADIERLAADG
ADAFLIGESLMRETDIGSQLRILLGNR

Sequences:

>Translated_267_residues
MNNTPDTLKKIVAHKYEELRDLKAHTALGELRVRARDMAPTHGFEAALRRKKGQGQTAIIAEVKKGSPSRGLIRADFDPL
EIARIYETNGATCLSVLTDQHFFMGRLENLTRIRGEVDLPLLRKDFILDPFQIYEARCAGADAILLITAILELPQMIDYI
TLARDLSLDILLEVHDERELDVALRTDCTLIGVNNRNLRTFTTDLATTGRLASMLPPEHLLVAESGISTRADIERLAADG
ADAFLIGESLMRETDIGSQLRILLGNR
>Mature_267_residues
MNNTPDTLKKIVAHKYEELRDLKAHTALGELRVRARDMAPTHGFEAALRRKKGQGQTAIIAEVKKGSPSRGLIRADFDPL
EIARIYETNGATCLSVLTDQHFFMGRLENLTRIRGEVDLPLLRKDFILDPFQIYEARCAGADAILLITAILELPQMIDYI
TLARDLSLDILLEVHDERELDVALRTDCTLIGVNNRNLRTFTTDLATTGRLASMLPPEHLLVAESGISTRADIERLAADG
ADAFLIGESLMRETDIGSQLRILLGNR

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=261, Percent_Identity=38.6973180076628, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=209, Percent_Identity=41.1483253588517, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 29742; Mature: 29742

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNTPDTLKKIVAHKYEELRDLKAHTALGELRVRARDMAPTHGFEAALRRKKGQGQTAII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
AEVKKGSPSRGLIRADFDPLEIARIYETNGATCLSVLTDQHFFMGRLENLTRIRGEVDLP
EEECCCCCCCCEEEECCCHHHEEEEEECCCCEEEHHHHCCHHHHHHHHHHHHHCCCCCCC
LLRKDFILDPFQIYEARCAGADAILLITAILELPQMIDYITLARDLSLDILLEVHDEREL
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
DVALRTDCTLIGVNNRNLRTFTTDLATTGRLASMLPPEHLLVAESGISTRADIERLAADG
EEEEECCEEEEECCCCCCEEEEHHHHHCCHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
ADAFLIGESLMRETDIGSQLRILLGNR
CCEEEHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MNNTPDTLKKIVAHKYEELRDLKAHTALGELRVRARDMAPTHGFEAALRRKKGQGQTAII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEE
AEVKKGSPSRGLIRADFDPLEIARIYETNGATCLSVLTDQHFFMGRLENLTRIRGEVDLP
EEECCCCCCCCEEEECCCHHHEEEEEECCCCEEEHHHHCCHHHHHHHHHHHHHCCCCCCC
LLRKDFILDPFQIYEARCAGADAILLITAILELPQMIDYITLARDLSLDILLEVHDEREL
HHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCE
DVALRTDCTLIGVNNRNLRTFTTDLATTGRLASMLPPEHLLVAESGISTRADIERLAADG
EEEEECCEEEEECCCCCCEEEEHHHHHCCHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
ADAFLIGESLMRETDIGSQLRILLGNR
CCEEEHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA