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The map label for this gene is bcc [H]

Identifier: 118578483

GI number: 118578483

Start: 41488

End: 41877

Strand: Direct

Name: bcc [H]

Synonym: Ppro_0035

Alternate gene names: 118578483

Gene position: 41488-41877 (Clockwise)

Preceding gene: 118578482

Following gene: 118578485

Centisome position: 1.04

GC content: 62.05

Gene sequence:

>390_bases
GTGCAGCTAACCTTAACAATAGACTCGAAAAAATACGTCGTAGACGTTGAAATCGTCGAAGGCGAAGAAGTCCGCATGCC
GGCGGCCGCGCCGGTTCCCGCCGCCACCATCAGCTCCCAGCCGGTGACCCCGATTGTTCCGGTCGCCACCGCGCCTGCCG
CCGACGGCCTGCCGGACGACAAGGTCTGCCGCAGCCCCATCGCCGGCGTTGTCTTCAAGGTCACCAGCGAAGTGGGCCAG
GAGATCAAGCAGGACGACCTGCTGTTGGTGCTTGAGGCCATGAAGATGGAGACCAACATCACGGCGCATGTGGCCGGCAA
GATCAAGGCCATCCACGTAAGCCCGGGCGAGGCCGTGAAGAACGGCCAGGTCCTGGTGGAATTCGAATAG

Upstream 100 bases:

>100_bases
CATGCAGGGGCGTGTTGCACTGCACGGGGCACGTATCAGCAGTATCTAGAAACGCGCATACATCCATGACTGTAAGAATA
TCTTTCAGAGGAGACTCGAC

Downstream 100 bases:

>100_bases
TCGCCAGCCTAAACCCCTCCAAACCTCCCCTTATCAGGGGAGACTGAGGGGGGTGGCAGTACAACCGGAAGCGCCCCGCG
AACCGAAAGGTTCCGCGGGG

Product: biotin/lipoyl attachment domain-containing protein

Products: propanoyl-CoA; CO2

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MQLTLTIDSKKYVVDVEIVEGEEVRMPAAAPVPAATISSQPVTPIVPVATAPAADGLPDDKVCRSPIAGVVFKVTSEVGQ
EIKQDDLLLVLEAMKMETNITAHVAGKIKAIHVSPGEAVKNGQVLVEFE

Sequences:

>Translated_129_residues
MQLTLTIDSKKYVVDVEIVEGEEVRMPAAAPVPAATISSQPVTPIVPVATAPAADGLPDDKVCRSPIAGVVFKVTSEVGQ
EIKQDDLLLVLEAMKMETNITAHVAGKIKAIHVSPGEAVKNGQVLVEFE
>Mature_129_residues
MQLTLTIDSKKYVVDVEIVEGEEVRMPAAAPVPAATISSQPVTPIVPVATAPAADGLPDDKVCRSPIAGVVFKVTSEVGQ
EIKQDDLLLVLEAMKMETNITAHVAGKIKAIHVSPGEAVKNGQVLVEFE

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 4.1.1.41

Molecular weight: Translated: 13613; Mature: 13613

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTLTIDSKKYVVDVEIVEGEEVRMPAAAPVPAATISSQPVTPIVPVATAPAADGLPDD
CEEEEEECCCEEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
KVCRSPIAGVVFKVTSEVGQEIKQDDLLLVLEAMKMETNITAHVAGKIKAIHVSPGEAVK
HHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCEEEEEECEEEEEEECCCCCCC
NGQVLVEFE
CCEEEEEEC
>Mature Secondary Structure
MQLTLTIDSKKYVVDVEIVEGEEVRMPAAAPVPAATISSQPVTPIVPVATAPAADGLPDD
CEEEEEECCCEEEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
KVCRSPIAGVVFKVTSEVGQEIKQDDLLLVLEAMKMETNITAHVAGKIKAIHVSPGEAVK
HHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCEEEEEECEEEEEEECCCCCCC
NGQVLVEFE
CCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-methylmalonyl-CoA

Specific reaction: (S)-methylmalonyl-CoA = propanoyl-CoA + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8431283; 12397186 [H]