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The map label for this gene is manA [H]

Identifier: 118480302

GI number: 118480302

Start: 5016573

End: 5017517

Strand: Reverse

Name: manA [H]

Synonym: BALH_4763

Alternate gene names: 118480302

Gene position: 5017517-5016573 (Counterclockwise)

Preceding gene: 118480303

Following gene: 118480301

Centisome position: 95.44

GC content: 35.56

Gene sequence:

>945_bases
ATGACAGAACCGTTATTTTTTGCACCCATTTTTAAAGAAAGAATTTGGGGTGGTACGAAATTAACTTCTTTCGGATATGA
AATACCATCAGAACAAACGGGAGAATGTTGGGCTTTTGCTGCGCATCAAAATGGACAAAGTGTAGTTAAAGATGGAAAGT
ATAAAGGCTTGTCTTTAGGACAATTGTGGAATAATCATCGAGAATTATTTGGGGGTATTGAGGGGGATTGTTTCCCTCTT
CTTACAAAAATTTTAGATGCAAATCGTGACTTATCTGTTCAAGTACATCCGAATGATGAATATGCACGTATAAATGAGAA
TGGTGAGCTAGGAAAGACTGAATGCTGGTATGTCATTGATTGTAAAGAAGGTGCTGAAATTATTTATGGGCATCATGCAA
AGACAAAGGATGAACTAGTAGAGATGGTGGAACAAGAAGAGTGGGACAAGCTATTACAACGTGTAAAGGTGAAGCCAGGT
GATTTCTTCTTTGTTCCAAGCGGGACTGTTCATGCAATCGGTGAAGGTATTTTAATATTAGAAACGCAACAAAACTCTGA
TACTACTTATCGGTTATATGATTATAATAGAAGAGATTCAGAGGGGAAACTGCGTGAACTCCATCTTGAGAAAAGTATGG
AAGTAATAGAGACACCATTTGTTTCAATGCAACAATCTGTTCAATATGAAGAAATAGAAGATTTATATGTAACAAAATTT
ATTGAATGTCCTTATTTTTCAGTGGAAAAATGGGAATTAGATGGAGTGGTTAATTTAACGCAAAAAAATCCATTTCTTCT
TTTAAGTGTAATAGATGGAAAATGCGAGCTAATACACGGTATTGAAAAGTATCAATTGGAGCAAGGAGATCATCTCATAT
TACCAAGCGATTTTGGGGAATATAGAGTGGTAGGACGTGCTGAATTTATTATTGCGAGTGTATAA

Upstream 100 bases:

>100_bases
TTATGGATGATAGTTATAGAGAGAGATTAATATCTGTCCAAACGAAAGAAGAAGCACATAAGTTATTAGATGACATCGTA
TAAAATGGAGGATTTTAATC

Downstream 100 bases:

>100_bases
GAGATGAAATATAAGAGGAGAGAGTATCGTCGACAAAATATGTTCGACAATACCCTCTCTTTTTTTATATGATTTTTGCT
ATACTAAACTGTACTATAAT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTEPLFFAPIFKERIWGGTKLTSFGYEIPSEQTGECWAFAAHQNGQSVVKDGKYKGLSLGQLWNNHRELFGGIEGDCFPL
LTKILDANRDLSVQVHPNDEYARINENGELGKTECWYVIDCKEGAEIIYGHHAKTKDELVEMVEQEEWDKLLQRVKVKPG
DFFFVPSGTVHAIGEGILILETQQNSDTTYRLYDYNRRDSEGKLRELHLEKSMEVIETPFVSMQQSVQYEEIEDLYVTKF
IECPYFSVEKWELDGVVNLTQKNPFLLLSVIDGKCELIHGIEKYQLEQGDHLILPSDFGEYRVVGRAEFIIASV

Sequences:

>Translated_314_residues
MTEPLFFAPIFKERIWGGTKLTSFGYEIPSEQTGECWAFAAHQNGQSVVKDGKYKGLSLGQLWNNHRELFGGIEGDCFPL
LTKILDANRDLSVQVHPNDEYARINENGELGKTECWYVIDCKEGAEIIYGHHAKTKDELVEMVEQEEWDKLLQRVKVKPG
DFFFVPSGTVHAIGEGILILETQQNSDTTYRLYDYNRRDSEGKLRELHLEKSMEVIETPFVSMQQSVQYEEIEDLYVTKF
IECPYFSVEKWELDGVVNLTQKNPFLLLSVIDGKCELIHGIEKYQLEQGDHLILPSDFGEYRVVGRAEFIIASV
>Mature_313_residues
TEPLFFAPIFKERIWGGTKLTSFGYEIPSEQTGECWAFAAHQNGQSVVKDGKYKGLSLGQLWNNHRELFGGIEGDCFPLL
TKILDANRDLSVQVHPNDEYARINENGELGKTECWYVIDCKEGAEIIYGHHAKTKDELVEMVEQEEWDKLLQRVKVKPGD
FFFVPSGTVHAIGEGILILETQQNSDTTYRLYDYNRRDSEGKLRELHLEKSMEVIETPFVSMQQSVQYEEIEDLYVTKFI
ECPYFSVEKWELDGVVNLTQKNPFLLLSVIDGKCELIHGIEKYQLEQGDHLILPSDFGEYRVVGRAEFIIASV

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 36060; Mature: 35929

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPLFFAPIFKERIWGGTKLTSFGYEIPSEQTGECWAFAAHQNGQSVVKDGKYKGLSLG
CCCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCHH
QLWNNHRELFGGIEGDCFPLLTKILDANRDLSVQVHPNDEYARINENGELGKTECWYVID
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEEE
CKEGAEIIYGHHAKTKDELVEMVEQEEWDKLLQRVKVKPGDFFFVPSGTVHAIGEGILIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCEEEE
ETQQNSDTTYRLYDYNRRDSEGKLRELHLEKSMEVIETPFVSMQQSVQYEEIEDLYVTKF
EECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHE
IECPYFSVEKWELDGVVNLTQKNPFLLLSVIDGKCELIHGIEKYQLEQGDHLILPSDFGE
ECCCCCEEEEEECCCEEEEECCCCEEEEEEECCCEEEHHCHHHHHHCCCCEEEECCCCCC
YRVVGRAEFIIASV
EEEEEEEEEEEEEC
>Mature Secondary Structure 
TEPLFFAPIFKERIWGGTKLTSFGYEIPSEQTGECWAFAAHQNGQSVVKDGKYKGLSLG
CCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCHH
QLWNNHRELFGGIEGDCFPLLTKILDANRDLSVQVHPNDEYARINENGELGKTECWYVID
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEEE
CKEGAEIIYGHHAKTKDELVEMVEQEEWDKLLQRVKVKPGDFFFVPSGTVHAIGEGILIL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCCCEEEE
ETQQNSDTTYRLYDYNRRDSEGKLRELHLEKSMEVIETPFVSMQQSVQYEEIEDLYVTKF
EECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHE
IECPYFSVEKWELDGVVNLTQKNPFLLLSVIDGKCELIHGIEKYQLEQGDHLILPSDFGE
ECCCCCEEEEEECCCEEEEECCCCEEEEEEECCCEEEHHCHHHHHHCCCCEEEECCCCCC
YRVVGRAEFIIASV
EEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]