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The map label for this gene is bioC [H]

Identifier: 118479316

GI number: 118479316

Start: 3945662

End: 3946471

Strand: Reverse

Name: bioC [H]

Synonym: BALH_3731

Alternate gene names: 118479316

Gene position: 3946471-3945662 (Counterclockwise)

Preceding gene: 118479317

Following gene: 118479315

Centisome position: 75.07

GC content: 34.69

Gene sequence:

>810_bases
ATGATCAACAAAACGTTACTACAAAAACGGTTTAACGTGGCAGCTGTATCCTACGATCAATATGCAAATGTACAAAAAAA
GATGGCACATTCATTACTTTCTACATTAGATCGGCGATATAGTGCAAATTCATCGATACGTATTTTAGAACTTGGATGCG
GGACAGGATATGTTACAGAGCAATTATCAAACTTATTTCCGAAAGCACATATTACAGCTATTGATTTTGCTGAAAGTATG
ATCGCAGTTGCCAAAACTAGACAAAATGTGAAAAATGTAATGTTTTACTGTGAGGATATCGAAAGGTTACAACTAGAAGA
AACATATGATGTCATTATTTCGAATGCCACATTTCAATGGCTAAATGATTTAAAACAAGTGATAAGAAATTTATTTCATC
ATTTGTCTATAGATGGGATATTACTCTTTTCAACGTTTGGACAGGAAACATTTCAAGAATTGCATACTTCGTTCCAGCGG
GCGAAAGAAGAAAAAAATATACAAAATGAAACATCGATTGGGCAACGTTTTTATTCGAAAAATCAATTACGCCATATATG
TGAGATAGAAACAGGGAATGTGCATGTTTCTGAAACATGTTACATAGAGAGATTTACAGAAGTTAGGGAGTTTTTACATT
CTATTCGAAAAGTAGGAGCGACCAATAGTAATGAAGAATCATATTGTCAAAGTCCCTCACTCTTTCGTGCGATGCTTCGC
ATATACGAAAGAGACTTCACGGAAAATGAAGGGATAATGGCGACGTATCACGCTTTATTTATGCATATAACAAAAGAGGG
GAAGAGATGA

Upstream 100 bases:

>100_bases
GCCAAGCTTAAGGTAGTAAGTGAGGCTGGACACGCATTATGTGTAACGAATTTTGAATATTGTGTAAATGAGATAATTCA
ATTTGTAGAGGGGATACGAC

Downstream 100 bases:

>100_bases
AATGAAACAAGTACAAACAAAAAGGGATTGGAAAAAACTTGCATATGACGTAGTAGAAGAAAAAATGATTGCAAAAGAGG
ATGCAATAGCGATATTAGAA

Product: biotin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTEQLSNLFPKAHITAIDFAESM
IAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQWLNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQR
AKEEKNIQNETSIGQRFYSKNQLRHICEIETGNVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLR
IYERDFTENEGIMATYHALFMHITKEGKR

Sequences:

>Translated_269_residues
MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTEQLSNLFPKAHITAIDFAESM
IAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQWLNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQR
AKEEKNIQNETSIGQRFYSKNQLRHICEIETGNVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLR
IYERDFTENEGIMATYHALFMHITKEGKR
>Mature_269_residues
MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTEQLSNLFPKAHITAIDFAESM
IAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQWLNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQR
AKEEKNIQNETSIGQRFYSKNQLRHICEIETGNVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLR
IYERDFTENEGIMATYHALFMHITKEGKR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=236, Percent_Identity=24.5762711864407, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786994, Length=273, Percent_Identity=25.6410256410256, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 31323; Mature: 31323

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTE
CCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
QLSNLFPKAHITAIDFAESMIAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQRAKEEKNIQNETSIGQRFYSK
HHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NQLRHICEIETGNVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLR
HHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHH
IYERDFTENEGIMATYHALFMHITKEGKR
HHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINKTLLQKRFNVAAVSYDQYANVQKKMAHSLLSTLDRRYSANSSIRILELGCGTGYVTE
CCCHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHH
QLSNLFPKAHITAIDFAESMIAVAKTRQNVKNVMFYCEDIERLQLEETYDVIISNATFQW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LNDLKQVIRNLFHHLSIDGILLFSTFGQETFQELHTSFQRAKEEKNIQNETSIGQRFYSK
HHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NQLRHICEIETGNVHVSETCYIERFTEVREFLHSIRKVGATNSNEESYCQSPSLFRAMLR
HHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHH
IYERDFTENEGIMATYHALFMHITKEGKR
HHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]