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The map label for this gene is ag45 [H]

Identifier: 118478733

GI number: 118478733

Start: 3304033

End: 3305367

Strand: Direct

Name: ag45 [H]

Synonym: BALH_3123

Alternate gene names: 118478733

Gene position: 3304033-3305367 (Clockwise)

Preceding gene: 118478730

Following gene: 118478739

Centisome position: 62.85

GC content: 37.6

Gene sequence:

>1335_bases
GTGACACGATTGGAACAATCAGCACATGAAGTAGCAAATTGGCAATATTATTTTGCAATTGCCGTATTTTTAGTCACGTA
CGGATTTATTATTTCTGAGAAATTGAATCGTGCTGTAATTGCACTATTCGGTGCTGCCATTATGATTATTTTTGGAATTG
TAGATTTACATACCGCTTTCACATCACATATTCAATGGGAAACGATTACCCTTTTAATTGGGATGATGATTCTCGTACAT
ATTACGAGTCAATCAGGCGTGTTTGAGTTTGTGGCCATTAAAGCAGCAAAAGCAGCTGGCGGAAAACCAATCCGCATTTT
ATTATTGCTATCCTTATTAACTGCTGTCGGATCAGCATTTTTGGACAACGTAACAACAGTCTTATTAATCGTACCTGTTA
CACTATCCATTACACGTATTTTAAAAGTAAACCCTGTTCCTTATTTGATTTCAGAAGTGCTATTTTCAAATATAGGCGGA
ACAGCAACATTAATCGGTGATCCACCGAACATTATGATCGGATCGGCAAATAAGCATTTAGATTTTAATGCCTTTTTACT
GAACTTAGCTCCAATCGTAATTATTATTTCTATCGTTACACTTGGCATTATTTACTTTATGTATCGCAATAAACTAAAAA
CAACACATGAGCAAATCGAAAAACTTATGGTATTAAACGAAAAAGATTACATTAAAGATCAAAGCCTCCTTTTAAAATCG
ATCACGATTTTAGGACTAACTATTTTAGGCTTTGTACTTCATTCGATTATTCACGTAGACGCTGCTGTTGTCGCGATGAC
AGGCGCTACACTTCTTATGTTAATCGGTGTGAAAGAACATGATATTGAAGATGTATTTGCCCACGTTGAATGGGTAACCA
TCTTCTTCTTTGCTGGACTATTCGTCCTCGTTGGCGGATTAATTGATATCGGGCTTATTTCTTCACTCGCAAAAGAAGTA
CTCGACGTAACAAATGGCGATATCGGTTTCGCTGCGGTACTTATTTTATGGGTATCAGGCATCGCATCTGCGACAATTGA
CAATATCCCATTTGTCGCAACGATGATCCCGCTTATTCAAGATTTAGCTACAGGACTCGGACTGTCTGTCGACTCTCCGC
AAATTGAAGTACTATGGTGGGCGTTATCACTTGGAGCTTGCTTAGGAGGAAACGGAACATTAATCGGAGCATCCGCAAAC
GTAGTCGTTGCTGGTATTGCAAAACGTGAAGGACATGCTTTCTCTTATATGGACTTCTTAAAAATTGGTTTGCCGTTAAC
AATCATTGCATTACTATTATCACACGCTTATATATATTTACGTTATTTAATGTAG

Upstream 100 bases:

>100_bases
TAAATAGTTTTCTTTCTTTTTTGAATTTGCTACAATATATTTTATCCCGTATGAATACAGCGAGATACATTTTGACAATT
GAATACATACTTTAAAGAAG

Downstream 100 bases:

>100_bases
ATGTTGTAGTGCGTGAAATTATATCGACGATTTTCTAGATGTATCGACGATTCGACAGAGTATATCGACTTACCGACAAA
TAATGACAACGAAAAAGGTA

Product: arsenical pump family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTRLEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHTAFTSHIQWETITLLIGMMILVH
ITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLISEVLFSNIGG
TATLIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFMYRNKLKTTHEQIEKLMVLNEKDYIKDQSLLLKS
ITILGLTILGFVLHSIIHVDAAVVAMTGATLLMLIGVKEHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEV
LDVTNGDIGFAAVLILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASAN
VVVAGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM

Sequences:

>Translated_444_residues
MTRLEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHTAFTSHIQWETITLLIGMMILVH
ITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLISEVLFSNIGG
TATLIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFMYRNKLKTTHEQIEKLMVLNEKDYIKDQSLLLKS
ITILGLTILGFVLHSIIHVDAAVVAMTGATLLMLIGVKEHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEV
LDVTNGDIGFAAVLILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASAN
VVVAGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM
>Mature_443_residues
TRLEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHTAFTSHIQWETITLLIGMMILVHI
TSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPVPYLISEVLFSNIGGT
ATLIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFMYRNKLKTTHEQIEKLMVLNEKDYIKDQSLLLKSI
TILGLTILGFVLHSIIHVDAAVVAMTGATLLMLIGVKEHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVL
DVTNGDIGFAAVLILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANV
VVAGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=450, Percent_Identity=36, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28574683, Length=497, Percent_Identity=33.4004024144869, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI28574681, Length=497, Percent_Identity=33.4004024144869, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI28574685, Length=497, Percent_Identity=33.4004024144869, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI28574678, Length=497, Percent_Identity=33.4004024144869, Blast_Score=243, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24581759, Length=497, Percent_Identity=33.4004024144869, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI19920704, Length=497, Percent_Identity=33.4004024144869, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI221472711, Length=491, Percent_Identity=27.9022403258656, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24581764, Length=491, Percent_Identity=27.9022403258656, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI45550608, Length=471, Percent_Identity=33.1210191082803, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI85724998, Length=454, Percent_Identity=25.7709251101322, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI62484377, Length=454, Percent_Identity=25.7709251101322, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24656008, Length=462, Percent_Identity=25.974025974026, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 48084; Mature: 47953

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHTAF
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSHIQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAF
HHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LDNVTTVLLIVPVTLSITRILKVNPVPYLISEVLFSNIGGTATLIGDPPNIMIGSANKHL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCC
DFNAFLLNLAPIVIIISIVTLGIIYFMYRNKLKTTHEQIEKLMVLNEKDYIKDQSLLLKS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ITILGLTILGFVLHSIIHVDAAVVAMTGATLLMLIGVKEHDIEDVFAHVEWVTIFFFAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FVLVGGLIDIGLISSLAKEVLDVTNGDIGFAAVLILWVSGIASATIDNIPFVATMIPLIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHAFSYMDFL
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHH
KIGLPLTIIALLLSHAYIYLRYLM
HHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRLEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHTAF
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSHIQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAF
HHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LDNVTTVLLIVPVTLSITRILKVNPVPYLISEVLFSNIGGTATLIGDPPNIMIGSANKHL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCC
DFNAFLLNLAPIVIIISIVTLGIIYFMYRNKLKTTHEQIEKLMVLNEKDYIKDQSLLLKS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ITILGLTILGFVLHSIIHVDAAVVAMTGATLLMLIGVKEHDIEDVFAHVEWVTIFFFAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
FVLVGGLIDIGLISSLAKEVLDVTNGDIGFAAVLILWVSGIASATIDNIPFVATMIPLIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHAFSYMDFL
HHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHH
KIGLPLTIIALLLSHAYIYLRYLM
HHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]