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The map label for this gene is hlY [C]

Identifier: 118477673

GI number: 118477673

Start: 2156250

End: 2156966

Strand: Reverse

Name: hlY [C]

Synonym: BALH_2005

Alternate gene names: 118477673

Gene position: 2156966-2156250 (Counterclockwise)

Preceding gene: 118477678

Following gene: 118477666

Centisome position: 41.03

GC content: 35.43

Gene sequence:

>717_bases
GTGTATGATATGGTAAGGGAAACGACATATTATTTTATAATAGTAGAAAGGATTGGCATTATGACTGAAAAAATGACACG
AATGACCCAATTTGTAAAAGAAGAAATTGCAAATGCAATAACACATGGTATCGGTGCCATTTTAAGCATCCCTGCCTTAA
TCATATTGATTATTCATGCTTCTAAGCATGGTACCGCATCAGCTGTAGTTGCATTTACTGTTTATGGTGTAAGCATGTTC
TTACTGTACTTGTTTTCGACATTGTTACATAGTATTCACCATCCAAAAGTAGAAAAATTATTTACTATACTAGATCACTC
AGCCATTTATTTATTAATCGCTGGCACATATACTCCTTTTTTACTTATCACGCTTCGTGGCCCATTAGGTTGGACGTTAC
TCGCAATTATATGGACACTAGCAATCGGGGGCATCATCTTCAAAATTTTCTTTGTACGTCGCTTTATTAAGGCATCAACT
CTATGTTATATCATAATGGGATGGCTCATAATCGTTGCTATTAAACCACTTTATGAAAATCTAACTGGACATGGTTTTTC
ACTACTTTTAGCAGGTGGAATTTTATATTCTGTAGGAGCTATATTCTTCCTTTGGGAAAAGTTACCTTTCAATCATGCCA
TTTGGCATCTTTTCGTATTAGGTGGTAGTGCAATGATGTTCTTCTGCGTACTCTTTTACGTCTTACCTACAGCATAA

Upstream 100 bases:

>100_bases
TTTGTCAAAAAAGTTTGAAAACGTCAACAAATCCATTGTCTTTTGTCAAAAAAATTCAAAAATATAATCAATTATACAAA
TTTCATTTTCTATTGCCCTT

Downstream 100 bases:

>100_bases
TAAAAAAGGTTTCAGCTTATATAAGCTGAAACCTTTTTTGTTACTTATGTAATTTTGATGCGATAACATCTTGTGTATGC
TTCGTTAACTCTTTAATATC

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MYDMVRETTYYFIIVERIGIMTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
LLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKAST
LCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Sequences:

>Translated_238_residues
MYDMVRETTYYFIIVERIGIMTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
LLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKAST
LCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
>Mature_238_residues
MYDMVRETTYYFIIVERIGIMTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
LLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKAST
LCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI52630445, Length=215, Percent_Identity=29.7674418604651, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI154759277, Length=264, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1789266, Length=216, Percent_Identity=42.5925925925926, Blast_Score=181, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71996356, Length=213, Percent_Identity=31.924882629108, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640324, Length=228, Percent_Identity=29.3859649122807, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 26815; Mature: 26815

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDMVRETTYYFIIVERIGIMTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCE
LLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYDMVRETTYYFIIVERIGIMTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVEKLFTILDHSAIYLLIAGTYTPF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCE
LLITLRGPLGWTLLAIIWTLAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]