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The map label for this gene is 118477678

Identifier: 118477678

GI number: 118477678

Start: 2159879

End: 2161072

Strand: Reverse

Name: 118477678

Synonym: BALH_2010

Alternate gene names: NA

Gene position: 2161072-2159879 (Counterclockwise)

Preceding gene: 118477680

Following gene: 118477673

Centisome position: 41.11

GC content: 33.17

Gene sequence:

>1194_bases
ATGTTACTTCTTTATTTCAAGCGAATTACTAGACAAAATATATTTTTTCACTATTATTTCTCTAAATATAAGTTGCAAAA
CTCATTTTATTGTTATTTTTGTAAATGCACCCCTCTATTTTTTTACAATTACTTAAACATTCATCCATGTTATACACTGT
ATTCCTTAACAACATTTCGGTACAATATAATTACAACGATTTTAAATGAGGTGATGTTCATGGCAAAGCGCTATGAAAAT
ATGGATAATGTTAGCACAAAAAAATCAATTCGTTCTTTTATACGCTGGCGTAAAGAACGAAAGCAAAACAAAAAAGATTT
TTCTTTCTTAGTAGAACAATCACCCGTTAAACAAAGTGCATTTTTGCAAAATAATGTTGAAAAAACGACTGTCACATGGA
TTGGGCATTCCACTTTTCTTATCCAAACGAATGGAATTAATATATTAACGGATCCAGTATGGGCCAATAAATTAAAATTA
GTCCAAAGACTTACAGAACCTGGACTTTCTATAAAAGAACTACCTAAAATTGATATCGTTCTTCTTTCACATGGTCATTA
TGATCACTTAGATTTTTCAACACTCCGCCAACTGAACGATGACGTATTATACTTAGTGCCCATCGGGTTAAAAAAATTAT
TTACTCGTAAAAAATTCAACAATGTAGAAGAGTATAAATGGTGGGAAAGTACGACTATTGATAAGGTTTCCTTTCACTTC
GTACCTGCTCAGCACTGGACGAGAAGATCATTATTTGATATGAATACATCTCACTGGGGTGGATGGATTATTAAGAATGA
CAATATGGAGGAAACCATTTATTTTTGCGGAGATAGTGGTTATTTCCAAGGCTTCAAAGAAATTGGCAAACGCTTTTCAA
TTGATATTGCCCTTATGCCAATTGGAGCTTATGAACCAGAATGGTTTATGAAAATATCTCACGTTTCACCTGAAGAAGCA
GTGCAAGCTTATTTAGATTTACATGCTACACACTTTATACCAATGCATTACGGGGCTTTTGCACTCGCTGATGAAACACC
TCGCGAGGCAATAACAAGGCTTCGAAATAATTGGAATTTACGTATGTTACCGTGGGAACAACTGCATGTACTCTTTTTAG
GTCAAACTTTCACTTATGATAGCGAAACACTTACTAAAAAAGTGAATGAAAAAATTGAAACGTTACATGTATAA

Upstream 100 bases:

>100_bases
TCTATCCTAAATTTAAATAGGTTATGTTTATCATAACAAAAGTTAACACTACGAGAAAATTGTTTACTACATTTGTTCAC
GAAATCGTACGAATTTACGT

Downstream 100 bases:

>100_bases
CGTAACTACTTATTTTCTATATCCAACATATAATATAGAAAATCATAAAGTGAAACTTTAATCAGTGGGTGTTTTCTATG
AATGAATATTTACAGACTCG

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MLLLYFKRITRQNIFFHYYFSKYKLQNSFYCYFCKCTPLFFYNYLNIHPCYTLYSLTTFRYNIITTILNEVMFMAKRYEN
MDNVSTKKSIRSFIRWRKERKQNKKDFSFLVEQSPVKQSAFLQNNVEKTTVTWIGHSTFLIQTNGINILTDPVWANKLKL
VQRLTEPGLSIKELPKIDIVLLSHGHYDHLDFSTLRQLNDDVLYLVPIGLKKLFTRKKFNNVEEYKWWESTTIDKVSFHF
VPAQHWTRRSLFDMNTSHWGGWIIKNDNMEETIYFCGDSGYFQGFKEIGKRFSIDIALMPIGAYEPEWFMKISHVSPEEA
VQAYLDLHATHFIPMHYGAFALADETPREAITRLRNNWNLRMLPWEQLHVLFLGQTFTYDSETLTKKVNEKIETLHV

Sequences:

>Translated_397_residues
MLLLYFKRITRQNIFFHYYFSKYKLQNSFYCYFCKCTPLFFYNYLNIHPCYTLYSLTTFRYNIITTILNEVMFMAKRYEN
MDNVSTKKSIRSFIRWRKERKQNKKDFSFLVEQSPVKQSAFLQNNVEKTTVTWIGHSTFLIQTNGINILTDPVWANKLKL
VQRLTEPGLSIKELPKIDIVLLSHGHYDHLDFSTLRQLNDDVLYLVPIGLKKLFTRKKFNNVEEYKWWESTTIDKVSFHF
VPAQHWTRRSLFDMNTSHWGGWIIKNDNMEETIYFCGDSGYFQGFKEIGKRFSIDIALMPIGAYEPEWFMKISHVSPEEA
VQAYLDLHATHFIPMHYGAFALADETPREAITRLRNNWNLRMLPWEQLHVLFLGQTFTYDSETLTKKVNEKIETLHV
>Mature_397_residues
MLLLYFKRITRQNIFFHYYFSKYKLQNSFYCYFCKCTPLFFYNYLNIHPCYTLYSLTTFRYNIITTILNEVMFMAKRYEN
MDNVSTKKSIRSFIRWRKERKQNKKDFSFLVEQSPVKQSAFLQNNVEKTTVTWIGHSTFLIQTNGINILTDPVWANKLKL
VQRLTEPGLSIKELPKIDIVLLSHGHYDHLDFSTLRQLNDDVLYLVPIGLKKLFTRKKFNNVEEYKWWESTTIDKVSFHF
VPAQHWTRRSLFDMNTSHWGGWIIKNDNMEETIYFCGDSGYFQGFKEIGKRFSIDIALMPIGAYEPEWFMKISHVSPEEA
VQAYLDLHATHFIPMHYGAFALADETPREAITRLRNNWNLRMLPWEQLHVLFLGQTFTYDSETLTKKVNEKIETLHV

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=310, Percent_Identity=36.7741935483871, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI170932481, Length=310, Percent_Identity=36.7741935483871, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17543102, Length=250, Percent_Identity=34, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI25148824, Length=250, Percent_Identity=34, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17543100, Length=250, Percent_Identity=34, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17543104, Length=232, Percent_Identity=36.2068965517241, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325154, Length=280, Percent_Identity=33.5714285714286, Blast_Score=149, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47403; Mature: 47403

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLLYFKRITRQNIFFHYYFSKYKLQNSFYCYFCKCTPLFFYNYLNIHPCYTLYSLTTFR
CEEEEEEHHHHCCEEEEEEEEEEEECCCEEEEEEEECHHHHHHCCCCCCHHHHHHHHHHH
YNIITTILNEVMFMAKRYENMDNVSTKKSIRSFIRWRKERKQNKKDFSFLVEQSPVKQSA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
FLQNNVEKTTVTWIGHSTFLIQTNGINILTDPVWANKLKLVQRLTEPGLSIKELPKIDIV
HHHCCCCEEEEEEEECEEEEEEECCCEEEECCCHHHHHHHHHHHHCCCCCHHHCCCEEEE
LLSHGHYDHLDFSTLRQLNDDVLYLVPIGLKKLFTRKKFNNVEEYKWWESTTIDKVSFHF
EEECCCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEE
VPAQHWTRRSLFDMNTSHWGGWIIKNDNMEETIYFCGDSGYFQGFKEIGKRFSIDIALMP
ECCCHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEE
IGAYEPEWFMKISHVSPEEAVQAYLDLHATHFIPMHYGAFALADETPREAITRLRNNWNL
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHCCCCE
RMLPWEQLHVLFLGQTFTYDSETLTKKVNEKIETLHV
EEECHHHEEEEEEECEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLLYFKRITRQNIFFHYYFSKYKLQNSFYCYFCKCTPLFFYNYLNIHPCYTLYSLTTFR
CEEEEEEHHHHCCEEEEEEEEEEEECCCEEEEEEEECHHHHHHCCCCCCHHHHHHHHHHH
YNIITTILNEVMFMAKRYENMDNVSTKKSIRSFIRWRKERKQNKKDFSFLVEQSPVKQSA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHH
FLQNNVEKTTVTWIGHSTFLIQTNGINILTDPVWANKLKLVQRLTEPGLSIKELPKIDIV
HHHCCCCEEEEEEEECEEEEEEECCCEEEECCCHHHHHHHHHHHHCCCCCHHHCCCEEEE
LLSHGHYDHLDFSTLRQLNDDVLYLVPIGLKKLFTRKKFNNVEEYKWWESTTIDKVSFHF
EEECCCCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEE
VPAQHWTRRSLFDMNTSHWGGWIIKNDNMEETIYFCGDSGYFQGFKEIGKRFSIDIALMP
ECCCHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEE
IGAYEPEWFMKISHVSPEEAVQAYLDLHATHFIPMHYGAFALADETPREAITRLRNNWNL
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHCCCCE
RMLPWEQLHVLFLGQTFTYDSETLTKKVNEKIETLHV
EEECHHHEEEEEEECEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]