| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is lysA [H]
Identifier: 118476980
GI number: 118476980
Start: 1421517
End: 1422866
Strand: Direct
Name: lysA [H]
Synonym: BALH_1275
Alternate gene names: 118476980
Gene position: 1421517-1422866 (Clockwise)
Preceding gene: 118476979
Following gene: 118476981
Centisome position: 27.04
GC content: 40.3
Gene sequence:
>1350_bases ATGAGTTTTAGAGGAAATAAGGGAGGAATTCAAATGTATTTACACGGCACAAGCCGAATCAATGGGCAAGGACACTTAGA AATTGGAGGGTGCGATACGACGCAGCTAGCAAAACAATACGGAACACCGCTTTATGTATACGATGAAGAGTCAATTCGAG GAAAGTGCCGCGCATTTCATCGTGCTTTTAAAGAAAGTGGGTTCTCTTATCAAGTAGCATATGCAAGCAAGGCGTTCTTG TGCATGGAGATGTGCCGAGTAGCTCGTGAAGAGAATATGTCATTAGACGTTGTTTCTGGAGGGGAATTATATACTGCGCT TCAAGCAGGATTTCCGGCATCACGCATTCATTTTCACGGCAATAATAAAACAGAAGAAGAAATCGTGATGGCTCTTCAGG CGAATATTGGTTGTTTTGTTGTAGATAATTTCTTGGAATTAGAAATTTTGCATGATTTAGCAGTGCAAAATGGGAAATTT GTGAACATATTAATTCGTGTAACACCTGGAGTAGAGGCGCACACACATGAATATATTACAACAGGTCAAGATGATTCGAA ATTTGGATTTGGCGTGTCAAATGGTCAAGCGATGCAGGCGATTGAGCTTGCTTTACAAAAATCAAATTATAACGTGTTAG GGATTCATTCACATATCGGATCACAAATATTTGAAACGGCTGGCTTTGTGCGAGCGATTGAAGTTCTTCATCAATTTTTA GAAGAAGTGAGAGAGCGAACAAACTATGTAGTAAAAGTGCTAAATGTGGGCGGAGGATTTGGAATACGCTACACAGAGTC AGATACACCATTAACTCTTGAGACATACGTGCGAGCTGTAACAAGTGCAGTGAGAGAACAATTTACAGTATGTAATTATC CATTGCCAGAAATATGGGTTGAGCCAGGTCGTAGCATTGTAGGTGATGCTGGAACGACACTTTATACAGTCGGATCTGTG AAAGACATTCCTGGTATTCGGAAATATGTATCAGTGGATGGTGGAATGACTGATAATTTAAGACCTGCTTTATATAACGC TCGTTATGAAGCAATGTTAGCAAATCGAGGGAATGATGAGAATGAGGAGACTGTTTCGATTGCAGGCAAATGTTGTGAGA GCGGAGATATGTTAATTTGGGATATTACTTTACCGAAAGTTGCTTCTGCCGATTTACTAGCGATTTCTTGTACAGGGGCA TACGGGTACTCGATGGCGAATAATTATAATCGGATTCGTAGACCAGCTGTCGTCTTCGTGAAAGGTGGTACATCACAAAT TGTTGTAGAGCGCGAAACATATGAAAATATTATTGGGAACGATCGCATACGTATTAAAGAACTTGTTTAA
Upstream 100 bases:
>100_bases TTCAATATATATTTTTCCTAATAAGAAACGCGTGTGAACATTGTTCCGCGCGTTTTTTGTCTATCTAAAAGCGTGCTGCA ATGAATAGAGGATTGGGGTT
Downstream 100 bases:
>100_bases GAGAGGAAAAGGAGTTGTTCGGATGGGCAATTCCTTTTTTGTAAAATAAAATAATTAAAATATATCGGAAAACTAGGATT GAAAAAAATCAGAATTGTGA
Product: diaminopimelate decarboxylase
Products: NA
Alternate protein names: DAP decarboxylase [H]
Number of amino acids: Translated: 449; Mature: 448
Protein sequence:
>449_residues MSFRGNKGGIQMYLHGTSRINGQGHLEIGGCDTTQLAKQYGTPLYVYDEESIRGKCRAFHRAFKESGFSYQVAYASKAFL CMEMCRVAREENMSLDVVSGGELYTALQAGFPASRIHFHGNNKTEEEIVMALQANIGCFVVDNFLELEILHDLAVQNGKF VNILIRVTPGVEAHTHEYITTGQDDSKFGFGVSNGQAMQAIELALQKSNYNVLGIHSHIGSQIFETAGFVRAIEVLHQFL EEVRERTNYVVKVLNVGGGFGIRYTESDTPLTLETYVRAVTSAVREQFTVCNYPLPEIWVEPGRSIVGDAGTTLYTVGSV KDIPGIRKYVSVDGGMTDNLRPALYNARYEAMLANRGNDENEETVSIAGKCCESGDMLIWDITLPKVASADLLAISCTGA YGYSMANNYNRIRRPAVVFVKGGTSQIVVERETYENIIGNDRIRIKELV
Sequences:
>Translated_449_residues MSFRGNKGGIQMYLHGTSRINGQGHLEIGGCDTTQLAKQYGTPLYVYDEESIRGKCRAFHRAFKESGFSYQVAYASKAFL CMEMCRVAREENMSLDVVSGGELYTALQAGFPASRIHFHGNNKTEEEIVMALQANIGCFVVDNFLELEILHDLAVQNGKF VNILIRVTPGVEAHTHEYITTGQDDSKFGFGVSNGQAMQAIELALQKSNYNVLGIHSHIGSQIFETAGFVRAIEVLHQFL EEVRERTNYVVKVLNVGGGFGIRYTESDTPLTLETYVRAVTSAVREQFTVCNYPLPEIWVEPGRSIVGDAGTTLYTVGSV KDIPGIRKYVSVDGGMTDNLRPALYNARYEAMLANRGNDENEETVSIAGKCCESGDMLIWDITLPKVASADLLAISCTGA YGYSMANNYNRIRRPAVVFVKGGTSQIVVERETYENIIGNDRIRIKELV >Mature_448_residues SFRGNKGGIQMYLHGTSRINGQGHLEIGGCDTTQLAKQYGTPLYVYDEESIRGKCRAFHRAFKESGFSYQVAYASKAFLC MEMCRVAREENMSLDVVSGGELYTALQAGFPASRIHFHGNNKTEEEIVMALQANIGCFVVDNFLELEILHDLAVQNGKFV NILIRVTPGVEAHTHEYITTGQDDSKFGFGVSNGQAMQAIELALQKSNYNVLGIHSHIGSQIFETAGFVRAIEVLHQFLE EVRERTNYVVKVLNVGGGFGIRYTESDTPLTLETYVRAVTSAVREQFTVCNYPLPEIWVEPGRSIVGDAGTTLYTVGSVK DIPGIRKYVSVDGGMTDNLRPALYNARYEAMLANRGNDENEETVSIAGKCCESGDMLIWDITLPKVASADLLAISCTGAY GYSMANNYNRIRRPAVVFVKGGTSQIVVERETYENIIGNDRIRIKELV
Specific function: Lysine biosynthesis; last step. [C]
COG id: COG0019
COG function: function code E; Diaminopimelate decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]
Homologues:
Organism=Escherichia coli, GI1789203, Length=421, Percent_Identity=29.6912114014252, Blast_Score=140, Evalue=2e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR002986 - InterPro: IPR022643 - InterPro: IPR022657 - InterPro: IPR022644 - InterPro: IPR022653 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: =4.1.1.20 [H]
Molecular weight: Translated: 49663; Mature: 49532
Theoretical pI: Translated: 5.81; Mature: 5.81
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFRGNKGGIQMYLHGTSRINGQGHLEIGGCDTTQLAKQYGTPLYVYDEESIRGKCRAFH CCCCCCCCCEEEEEEECCEECCCEEEEECCCCHHHHHHHHCCEEEEECCHHHHHHHHHHH RAFKESGFSYQVAYASKAFLCMEMCRVAREENMSLDVVSGGELYTALQAGFPASRIHFHG HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHCCCCHHEEEECC NNKTEEEIVMALQANIGCFVVDNFLELEILHDLAVQNGKFVNILIRVTPGVEAHTHEYIT CCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEE TGQDDSKFGFGVSNGQAMQAIELALQKSNYNVLGIHSHIGSQIFETAGFVRAIEVLHQFL CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH EEVRERTNYVVKVLNVGGGFGIRYTESDTPLTLETYVRAVTSAVREQFTVCNYPLPEIWV HHHHHHHCEEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHEECCCCCHHHHC EPGRSIVGDAGTTLYTVGSVKDIPGIRKYVSVDGGMTDNLRPALYNARYEAMLANRGNDE CCCCEEECCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCHHHHCCHHEEEEECCCCCC NEETVSIAGKCCESGDMLIWDITLPKVASADLLAISCTGAYGYSMANNYNRIRRPAVVFV CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHCCHHHHCCCEEEEE KGGTSQIVVERETYENIIGNDRIRIKELV ECCCCEEEEEHHHHHHHHCCCCEEEEECC >Mature Secondary Structure SFRGNKGGIQMYLHGTSRINGQGHLEIGGCDTTQLAKQYGTPLYVYDEESIRGKCRAFH CCCCCCCCEEEEEEECCEECCCEEEEECCCCHHHHHHHHCCEEEEECCHHHHHHHHHHH RAFKESGFSYQVAYASKAFLCMEMCRVAREENMSLDVVSGGELYTALQAGFPASRIHFHG HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHCCCCHHEEEECC NNKTEEEIVMALQANIGCFVVDNFLELEILHDLAVQNGKFVNILIRVTPGVEAHTHEYIT CCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCEEE TGQDDSKFGFGVSNGQAMQAIELALQKSNYNVLGIHSHIGSQIFETAGFVRAIEVLHQFL CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH EEVRERTNYVVKVLNVGGGFGIRYTESDTPLTLETYVRAVTSAVREQFTVCNYPLPEIWV HHHHHHHCEEEEEEECCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHEECCCCCHHHHC EPGRSIVGDAGTTLYTVGSVKDIPGIRKYVSVDGGMTDNLRPALYNARYEAMLANRGNDE CCCCEEECCCCCEEEEECCCCCCCCCHHEEEECCCCCCCCCHHHHCCHHEEEEECCCCCC NEETVSIAGKCCESGDMLIWDITLPKVASADLLAISCTGAYGYSMANNYNRIRRPAVVFV CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHCCHHHHCCCEEEEE KGGTSQIVVERETYENIIGNDRIRIKELV ECCCCEEEEEHHHHHHHHCCCCEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2513554; 7934829; 1368705; 8969508; 9384377 [H]