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The map label for this gene is cysH

Identifier: 118476981

GI number: 118476981

Start: 1423394

End: 1424098

Strand: Direct

Name: cysH

Synonym: BALH_1276

Alternate gene names: 118476981

Gene position: 1423394-1424098 (Clockwise)

Preceding gene: 118476980

Following gene: 118476982

Centisome position: 27.08

GC content: 37.87

Gene sequence:

>705_bases
ATGTTGACGTATGAAACGTGGGAAGAAAATGATGTTTCATTTTCAGAAGAAGATGAAACGAAAGGCGCGCTATCAGTATT
AAGTTGGGCGTATAAAGAATATAAAAGTGAAATTGTATACGCATGTAGCTTCGGAGTGGAAGGGATGGTACTACTGCATC
TTATTAACCAAGTAAATCCATCTGCTAAAGTTGTATTTTTGGATACAAACGTACATTTTCAAGAAACGTATGAATTAATT
CAAAAAGTGCGGGAACGATTTCCTTCATTGAATATTATAGAAAAACAGCCAAAACTTACACTTGATGAACAAGACAAATT
GCATGGTGACAAGCTATGGGAAAGCAATCCTAATCTCTGTTGTAAGATTAGAAAAATTTTACCGTTAGAAGAATCATTAG
CGAATGAAAAAGCGTGGATATCAGGGTTGAGGAGGGAACAATCAGAAACGCGTAAGCATACAAAGTTTATAAATCAAGAT
CATCGTTTTCAATCTATTAAAGTTTGTCCGCTCATTCATTGGACGTGGAAAGAGGTATGGCGATATGTATACAAACATAG
CTTGCCGTATAACCCGCTGCATGATGTTGGATATCCAAGTATTGGGTGTGAGAAGTGTACGTTACCTGTAGGTGAGGGTG
GCGATTCGAGAGATGGTAGATGGGCCGGGAAAGTGAAAACTGAATGCGGTCTACATTACCAATAA

Upstream 100 bases:

>100_bases
TACGTTTAAAGTAAAAAGCGCTGACTAGAAAAACTAGAGGCGGTTTTAACCTATTTCATTAGGTTAAAACCGTCTTTTTG
CTTTTACAGGGGGAAAAAAC

Downstream 100 bases:

>100_bases
GATGAATTTGAAAATAAAGCTAAGAGAGGATATAGAAAATGAGTACAAGAAACGAATTAGTAAATCTTATAGATGAGACA
TATGACGTATCACAAATTGA

Product: phosphoadenylylsulfate reductase (thioredoxin)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ

Sequences:

>Translated_234_residues
MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
>Mature_234_residues
MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ

Specific function: Reduction of activated sulfate into sulfite

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily

Homologues:

Organism=Escherichia coli, GI1789121, Length=211, Percent_Identity=34.1232227488152, Blast_Score=112, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325425, Length=217, Percent_Identity=30.8755760368664, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSH_BACAH (A0RBN2)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_894132.1
- ProteinModelPortal:   A0RBN2
- SMR:   A0RBN2
- STRING:   A0RBN2
- EnsemblBacteria:   EBBACT00000068253
- GeneID:   4546888
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_1276
- NMPDR:   fig|412694.5.peg.1287
- eggNOG:   COG0175
- GeneTree:   EBGT00050000002870
- HOGENOM:   HBG758022
- OMA:   QVNPSAK
- ProtClustDB:   CLSK916236
- BioCyc:   BTHU412694:BALH_1276-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00063
- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR02055
- TIGRFAMs:   TIGR00434

Pfam domain/function: PF01507 PAPS_reduct

EC number: =1.8.4.8

Molecular weight: Translated: 27320; Mature: 27320

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCC
SAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLC
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHCCCCHHHCCCCCCE
CKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVW
EHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHH
RYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHCCCCCCC
>Mature Secondary Structure
MLTYETWEENDVSFSEEDETKGALSVLSWAYKEYKSEIVYACSFGVEGMVLLHLINQVNP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCC
SAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQDKLHGDKLWESNPNLC
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHCCCCHHHCCCCCCE
CKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVW
EHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHH
RYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA