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The map label for this gene is hisK [H]

Identifier: 118476974

GI number: 118476974

Start: 1415125

End: 1416141

Strand: Direct

Name: hisK [H]

Synonym: BALH_1268

Alternate gene names: 118476974

Gene position: 1415125-1416141 (Clockwise)

Preceding gene: 118476973

Following gene: 118476976

Centisome position: 26.92

GC content: 34.81

Gene sequence:

>1017_bases
ATGAAAGTGGATTATCACATTCATTTAGAAGAAGGACCATATTCAATAGGGTGGCTAGCTAAAATAAATGAAGCACTGCA
ACACTATGAACCGCTAAAAGAAGAAAAACATTCTATGGAATGGCTTGTGAAAACACAAGAACGCCTGCAAAGACGTGTGA
ATGAAGGGCCATTTACAACGAAATGGATTGATTTATATTTAGAAGAAGCATTGCGAAAAGGGATAAAAGAAGTTGGTATT
GTCGATCATTTATACCGTTTTTATGAAGCGAAAGAATACTATGAAAAATATGTTGATATTAGTGATTCAGGGCTTGGATG
TTTACAAAAGGAATGGTTAGACCAAGTAAGGGTAGCTTCAATACATGATTTTACAAAGGCAATTGAAGAGGCGAAAGAAC
GGTGGAGTAAAAGAGGTGTTACGCTTAAACTTGGAATTGAAGCGGATTATTTTATTGGTGGTGAACAAGAATTACAATCT
TTACTCGCATTAGGAGACTTTGATTATGTAATTGGTTCTGTTCATTTTTTAAATGGCTGGGGATTTGATAATCCAGATAC
GAAAGAATATTTCAAGGAACATGACTTATACGCTTTATATGATACGTTTTTCAAAACGGTTGAGTGCGCAGTTCGTTCTG
AGTTATTTGATATTATTGCTCATCTTGATAACATAAAAGTATTTAATTATCGGTTAGATGAGAATGAACAACTTTCTTAT
TACAAGGAAATTGCGCGTGCATTAGTAGAAACAAATACGGCAACGGAAATAAATGCAGGATTGTATTATCGTTATCCTGT
GCGCGAAATGTGCCCGAGTCCGCTCTATTTACAAGTATTAGCTAAACACGAAGTTCCGATTACACTTTCTTCAGATGCTC
ATTATCCAAACGATTTAGGAAAATATGTGGAAGAGAATGTAAAGACGTTACGTAATCATGATATTTCTCACTTAGCTACA
TTTACGAAACGAGTCAGAACGATGAGATTACTAGAAGAAGTAACAATTTCAAAATGA

Upstream 100 bases:

>100_bases
TATCATTAGAAGATATTATGGCGGAAGTGACAGAAAGAAATGGGAAGCTTTCGAGAGTAGGGGACAGAAGAGAAATAGAT
ACATTATAGGGGGAATAGGT

Downstream 100 bases:

>100_bases
TCACGATTTTTTGATGAAAACCGTTCTTTTTGTTCAAAATAAGAAAGAATAAAAAGGAGGGTAAGAAATGGCGAAACAAC
AAAATAAACAAAATGTACAA

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVNEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASIHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQS
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDENEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHDISHLAT
FTKRVRTMRLLEEVTISK

Sequences:

>Translated_338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVNEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASIHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQS
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDENEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHDISHLAT
FTKRVRTMRLLEEVTISK
>Mature_338_residues
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVNEGPFTTKWIDLYLEEALRKGIKEVGI
VDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVASIHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQS
LLALGDFDYVIGSVHFLNGWGFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDENEQLSY
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLGKYVEENVKTLRNHDISHLAT
FTKRVRTMRLLEEVTISK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 39730; Mature: 39730

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVNEGPFTT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KWIDLYLEEALRKGIKEVGIVDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQSLLALGDFDYVIGSVHFLNGW
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHCCHHHHHHHHHEECCC
GFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDENEQLSY
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLG
HHHHHHHHHHCCCCCEECCCEEEECCHHHHCCCCHHHHHHHHCCCCEEECCCCCCCHHHH
KYVEENVKTLRNHDISHLATFTKRVRTMRLLEEVTISK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVDYHIHLEEGPYSIGWLAKINEALQHYEPLKEEKHSMEWLVKTQERLQRRVNEGPFTT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KWIDLYLEEALRKGIKEVGIVDHLYRFYEAKEYYEKYVDISDSGLGCLQKEWLDQVRVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IHDFTKAIEEAKERWSKRGVTLKLGIEADYFIGGEQELQSLLALGDFDYVIGSVHFLNGW
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEECCHHHHHHHHHHCCHHHHHHHHHEECCC
GFDNPDTKEYFKEHDLYALYDTFFKTVECAVRSELFDIIAHLDNIKVFNYRLDENEQLSY
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
YKEIARALVETNTATEINAGLYYRYPVREMCPSPLYLQVLAKHEVPITLSSDAHYPNDLG
HHHHHHHHHHCCCCCEECCCEEEECCHHHHCCCCHHHHHHHHCCCCEEECCCCCCCHHHH
KYVEENVKTLRNHDISHLATFTKRVRTMRLLEEVTISK
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]