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The map label for this gene is hisE [H]

Identifier: 118476973

GI number: 118476973

Start: 1414724

End: 1415113

Strand: Direct

Name: hisE [H]

Synonym: BALH_1267

Alternate gene names: 118476973

Gene position: 1414724-1415113 (Clockwise)

Preceding gene: 118476972

Following gene: 118476974

Centisome position: 26.91

GC content: 32.82

Gene sequence:

>390_bases
TTGGCCCAGCTTGCCATACGGGAGAAAAAACGTGTTTTCATTACAAAATTATATAGGGGGATACATATGGAAAATACCTT
CAAATTACTATTCGAAACAATTGGAGAACGAAAGAGAAATCCACTTCCTGAATCATATACAAATTACTTGTTTTCAAAAG
GAGAAGATAAAATTTTAAAGAAAATTGGTGAGGAATGCACGGAAGTAATTATCGCATCTAAAAATAATGATAAAGAAGAG
TTAGTGAAAGAAATGGTTGATGTATTGTATCACTGCTTCGTTTTATTAGCCGAAAAAAATATATCATTAGAAGATATTAT
GGCGGAAGTGACAGAAAGAAATGGGAAGCTTTCGAGAGTAGGGGACAGAAGAGAAATAGATACATTATAG

Upstream 100 bases:

>100_bases
TCGCTATGGAATAAAGGAGAAACGTCAGGTCATGTCCAACATGTGCAATCTCTTTATTTAGATTGTGATCAAGATTCAAT
TGTTGTTGTCGTAAAGCAAG

Downstream 100 bases:

>100_bases
GGGGAATAGGTATGAAAGTGGATTATCACATTCATTTAGAAGAAGGACCATATTCAATAGGGTGGCTAGCTAAAATAAAT
GAAGCACTGCAACACTATGA

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MAQLAIREKKRVFITKLYRGIHMENTFKLLFETIGERKRNPLPESYTNYLFSKGEDKILKKIGEECTEVIIASKNNDKEE
LVKEMVDVLYHCFVLLAEKNISLEDIMAEVTERNGKLSRVGDRREIDTL

Sequences:

>Translated_129_residues
MAQLAIREKKRVFITKLYRGIHMENTFKLLFETIGERKRNPLPESYTNYLFSKGEDKILKKIGEECTEVIIASKNNDKEE
LVKEMVDVLYHCFVLLAEKNISLEDIMAEVTERNGKLSRVGDRREIDTL
>Mature_128_residues
AQLAIREKKRVFITKLYRGIHMENTFKLLFETIGERKRNPLPESYTNYLFSKGEDKILKKIGEECTEVIIASKNNDKEEL
VKEMVDVLYHCFVLLAEKNISLEDIMAEVTERNGKLSRVGDRREIDTL

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 15082; Mature: 14951

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLAIREKKRVFITKLYRGIHMENTFKLLFETIGERKRNPLPESYTNYLFSKGEDKILK
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
KIGEECTEVIIASKNNDKEELVKEMVDVLYHCFVLLAEKNISLEDIMAEVTERNGKLSRV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHC
GDRREIDTL
CCCCCCCCC
>Mature Secondary Structure 
AQLAIREKKRVFITKLYRGIHMENTFKLLFETIGERKRNPLPESYTNYLFSKGEDKILK
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHH
KIGEECTEVIIASKNNDKEELVKEMVDVLYHCFVLLAEKNISLEDIMAEVTERNGKLSRV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHC
GDRREIDTL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA