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The map label for this gene is trpB [H]

Identifier: 118476813

GI number: 118476813

Start: 1246729

End: 1247922

Strand: Direct

Name: trpB [H]

Synonym: BALH_1100

Alternate gene names: 118476813

Gene position: 1246729-1247922 (Clockwise)

Preceding gene: 118476812

Following gene: 118476814

Centisome position: 23.72

GC content: 41.62

Gene sequence:

>1194_bases
ATGAACTACGCATATCCAGATGAAAAAGGTCACTACGGTATATACGGAGGACGATACGTTCCAGAAACGTTAATGCAATC
TGTATTAGAACTAGAAGAAGCATATAAAGAGGCGATGGAAGATGAAGCATTTCAAAAGGAATTAAATCATTATTTAAATA
CGTATGTTGGAAGAGAAACACCGCTTTATTTCGCTGAGAATATGACGGAGTATTGCGGAGGTGCAAAGATTTATTTAAAA
CGTGAAGATTTGAACCATACAGGAGCTCATAAAATTAACAATACAATTGGTCAGGCACTTCTTGCGGTGCGAATGGGCAA
GAAAAAAGTTGTCGCTGAAACAGGGGCTGGACAACACGGTGTTGCAACAGCTACGGTATGTGCCCTTCTCGGTTTAGAGT
GCGTCATCTTTATGGGAGAAGAAGATGTGAGACGTCAAAAATTAAATGTGTTTCGAATGGAATTACTCGGAGCGAAAGTA
GAAAGTGTAGCGGCAGGTAGCGGTACATTAAAAGATGCGGTAAACGAGGCGCTTCGTTACTGGGTTTCACATGTGCATGA
TACGCACTACATTATGGGATCTGTTCTCGGACCGCATCCATTCCCGCAAATTGTCCGTGATTTCCAAAGTGTAATTGGGA
ATGAGACGAAGAAACAATATGAAGAATTAGAAGGGAAGTTACCAGAAGCAGTCGTTGCTTGTATTGGTGGTGGGAGTAAC
GCAATGGGAATGTTTTATCCGTTCGTACACGATGAAGAAGTTGCTCTTTACGGCGTAGAAGCAGCTGGAAAAGGTGTTCA
TACAGAAAAGCATGCAGCAACTTTAACGAAAGGAAGCGTCGGTGTTTTACACGGATCAATGATGTATCTTCTACAAAATG
AAGAAGGTCAAATTCAAGAAGCGCACTCTATTTCAGCAGGGCTTGATTACCCAGGTGTTGGTCCAGAACATAGCTTGCTC
AAAGATATTGGTCGCGTTTCTTATCATTCCATTACTGATGATGAAGCGTTAGAAGCATTTCAATTATTAACGAAAAAAGA
AGGGATTATCCCGGCGCTAGAAAGCTCGCATGCTGTTGCATACGCATTGAAATTAGCGCCGCAAATGAAGGAAGACGAAG
GACTTGTCATTTGTTTATCCGGCCGTGGTGATAAAGATGTAGAGAGTATAAAACGTTATATGGAAGAGGTGTAA

Upstream 100 bases:

>100_bases
GGCCATATATGGTTGATGTGAGCAGCGGAGTAGAGACAGAAGGAAAGAAAGATGTAGAGAAAATAAAACAATTTATTATA
AAAGCGAAGGAGTGTTCTAA

Downstream 100 bases:

>100_bases
AAAATGGGAGTAGAAAGAATTAAAGCAGCATTTGAAAATGGTAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGG
TGGCCTTGAAATATTAAAAG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Sequences:

>Translated_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
>Mature_397_residues
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRETPLYFAENMTEYCGGAKIYLK
REDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKV
ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSN
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLL
KDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=55.1181102362205, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=57.7319587628866, Blast_Score=472, Evalue=1e-134,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43634; Mature: 43634

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEAFQKELNHYLNTYVGRET
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHG
CHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCC
VATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRY
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
WVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEELEGKLPEAVVACIGGGSN
HHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCC
AMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQE
CCCEEECCCCCCCEEEEEEHHCCCCCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHH
AHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
YALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
HHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA