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The map label for this gene is trpA [H]

Identifier: 118476814

GI number: 118476814

Start: 1247926

End: 1248702

Strand: Direct

Name: trpA [H]

Synonym: BALH_1101

Alternate gene names: 118476814

Gene position: 1247926-1248702 (Clockwise)

Preceding gene: 118476813

Following gene: 118476815

Centisome position: 23.74

GC content: 39.25

Gene sequence:

>777_bases
ATGGGAGTAGAAAGAATTAAAGCAGCATTTGAAAATGGTAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGGTGG
CCTTGAAATATTAAAAGAAAGAATTCGTTTTTTAGACGAAGCGGGAGCAAGCATCGTTGAAATTGGTATCCCGTTTTCAG
ATCCAGTCGCAGATGGCCCAACGATTCAAAGAGCAGGGAAACGAGCGCTAGATAGCGGTGTAACAGTAAAAGGCATTTTT
CAAGCATTAATAGAGGTAAGGAAAGAAGTGCAAATTCCGTTTGTACTCATGACATATTTAAATCCAGTACTTGCATTCGG
GAAAGAACGATTTATCGAGAACTGTATGGAAGCAGGGGTAGACGGTATTATCGTTCCGGATTTACCGTATGAAGAACAAG
ACATTATTGCTCCGTTACTTCGAGAGGCAAACATTGCGCTCATTCCACTTGTTACTGTTACGAGCCCAATTGAGCGGATC
AAAAAAATTATGAGTGAATCAGAAGGATTTGTCTACGCCGTTACAGTAGCGGGCGTAACAGGAGTACGTCAAAATTTTAA
AGATGAGATTCATAGTTACTTAGAAAAAGTAAAATCGCATACACATTTACCGGTAGTGGCAGGGTTCGGTATTTCAACAA
AGGAACATGTAGAAGAAATGGTTACAATATGTGATGGAGTTGTCGTTGGAAGTAAAGTGATTGAGCTATTAGAAAATGAA
AAACGAGAAGAAATATGTGAATTCATACAGGCAACAAAACAAAAAGAAGAGGCGTAA

Upstream 100 bases:

>100_bases
GCCGCAAATGAAGGAAGACGAAGGACTTGTCATTTGTTTATCCGGCCGTGGTGATAAAGATGTAGAGAGTATAAAACGTT
ATATGGAAGAGGTGTAAAAA

Downstream 100 bases:

>100_bases
GTCTCTTCTTTTTGTTTTGTGTAATAAATGTTAAAATATACAGAAAATACATATAATTTAGAGGGTGAGAAAGCATGCTA
AGACGGAAACTACTATATCT

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGPTIQRAGKRALDSGVTVKGIF
QALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERI
KKIMSESEGFVYAVTVAGVTGVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENE
KREEICEFIQATKQKEEA

Sequences:

>Translated_258_residues
MGVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGPTIQRAGKRALDSGVTVKGIF
QALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERI
KKIMSESEGFVYAVTVAGVTGVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENE
KREEICEFIQATKQKEEA
>Mature_257_residues
GVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGPTIQRAGKRALDSGVTVKGIFQ
ALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGVDGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERIK
KIMSESEGFVYAVTVAGVTGVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENEK
REEICEFIQATKQKEEA

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=250, Percent_Identity=35.2, Blast_Score=133, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6321412, Length=258, Percent_Identity=34.4961240310078, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 28385; Mature: 28254

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGP
CCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TIQRAGKRALDSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERIKKIMSESEGFVYAVTVAGVT
CEEEECCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
GVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KREEICEFIQATKQKEEA
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVERIKAAFENGKKAFIPYVMGGDGGLEILKERIRFLDEAGASIVEIGIPFSDPVADGP
CHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TIQRAGKRALDSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKERFIENCMEAGV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERIKKIMSESEGFVYAVTVAGVT
CEEEECCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHH
GVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENE
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KREEICEFIQATKQKEEA
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA