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The map label for this gene is ycbM [H]

Identifier: 118476035

GI number: 118476035

Start: 310113

End: 311135

Strand: Reverse

Name: ycbM [H]

Synonym: BALH_0277

Alternate gene names: 118476035

Gene position: 311135-310113 (Counterclockwise)

Preceding gene: 118476036

Following gene: 118476034

Centisome position: 5.92

GC content: 33.53

Gene sequence:

>1023_bases
GTGAAAAGCTTGAAGATTGATAAAATCCTCTTCCTTATTTCATTACAACTTATCATTTACGGGCTTTTACATATACAAAT
GGATCCAAAAGTAAAAATTTCTTTATTTATTACCCTTATCTTAATTACAATGTATCTCTTCTTTTCAAGAATACAATTTA
TTCAAAACCGCAAATCAATAGACACTAAATTAAGTCGTGCACTAAAGGGGAATTTACAAACGAGATTATTCACAAGTAAT
GATCAATCGTTCCATAATATCGTTTTTTCAATAAACGAACTAATAGCTGAATTAGAAAAGGTTCGGATTAAAGCAAAAAG
GTCTGAGGAATCTAGAAAACAACTTTTATCTAGTATCTCACACGATATCCGAACACCACTCACCTCCATTATTGGATATA
TCGATGCTTTAAAAGATGGGGTTGCTACTTCTGAAATAGAAAAGCAAGAATATCTTAAAATACTGTATATGAAATCAAAT
AACTTAAAGCATCTAGTTGATGAAATATTCAATATGGCAAAGCTAGACGCCAATGAATTTCCACTAAAAGAAGAAAAACT
CGATTTTTCTGAGGTTACTAGAGAAGTTTTGATCGAGTTTTTACCTGAAATCTCAAAACATAATATTAAACTACAAGTTC
TTATGCCAGAGTCTACTTGTCCTATCATTGCAGATCATCTAAGCCTTATGCGGATTATAGGTAATTTAATGAAAAATGCC
ATTTATTACGGAAAGGATGGGAAAATAATAGGAGTCGAACTACTAGAAACGGATGCAGCATATGAACTTCTTATTTGGGA
TAAAGGCCCTGGTATTCCAAAACATGATTTACAAAACGTATTTGAGCGAATGTACCGAAGCGAACAATCAAGAAACTCGT
CTTTTGGTGGTAGCGGGCTCGGCCTTTCTATTTCTAAAGCGCTCGTTGAGAGGAATGGTGGGCATATATGGGTTGAAAGT
ATTCCATGGGAACGAACCACTTTTGGCTTTTCCATTCCAAAACACAATACTTTTAAGAAATAG

Upstream 100 bases:

>100_bases
GTTATGGTACATATTCGAAAACTTAGAAAGAAAATAGAAACCGATCCTTCCAATCCAAAATTCATTCAAACTGTATGGGG
AATTGGCTATAAGTTTGTAG

Downstream 100 bases:

>100_bases
TTAAGAAATGATTAATATGCAGTTAAGCCTTCCTTTTTATCATGTAAGTAAGAACTTATAGAAAGTAGGTGTCTCCTATA
AACACAATTATAAAAACGAC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNRKSIDTKLSRALKGNLQTRLFTSN
DQSFHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVATSEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIEFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKIIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVERNGGHIWVES
IPWERTTFGFSIPKHNTFKK

Sequences:

>Translated_340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNRKSIDTKLSRALKGNLQTRLFTSN
DQSFHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVATSEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIEFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKIIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVERNGGHIWVES
IPWERTTFGFSIPKHNTFKK
>Mature_340_residues
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNRKSIDTKLSRALKGNLQTRLFTSN
DQSFHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSISHDIRTPLTSIIGYIDALKDGVATSEIEKQEYLKILYMKSN
NLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIEFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
IYYGKDGKIIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVERNGGHIWVES
IPWERTTFGFSIPKHNTFKK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=27.6515151515151, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=29.5081967213115, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=31.203007518797, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=28.5140562248996, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=244, Percent_Identity=28.6885245901639, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=26.25, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=26.1061946902655, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787894, Length=290, Percent_Identity=25.1724137931034, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=25.9574468085106, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=25.0936329588015, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=247, Percent_Identity=24.6963562753036, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=308, Percent_Identity=25, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=249, Percent_Identity=23.2931726907631, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=24.9134948096886, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39088; Mature: 39088

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNRKSI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTKLSRALKGNLQTRLFTSNDQSFHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSIS
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HDIRTPLTSIIGYIDALKDGVATSEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCC
PLKEEKLDFSEVTREVLIEFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
CCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
IYYGKDGKIIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGL
EEECCCCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLSISKALVERNGGHIWVESIPWERTTFGFSIPKHNTFKK
CHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKSLKIDKILFLISLQLIIYGLLHIQMDPKVKISLFITLILITMYLFFSRIQFIQNRKSI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTKLSRALKGNLQTRLFTSNDQSFHNIVFSINELIAELEKVRIKAKRSEESRKQLLSSIS
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HDIRTPLTSIIGYIDALKDGVATSEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCC
PLKEEKLDFSEVTREVLIEFLPEISKHNIKLQVLMPESTCPIIADHLSLMRIIGNLMKNA
CCCHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHC
IYYGKDGKIIGVELLETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGL
EEECCCCCEEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
GLSISKALVERNGGHIWVESIPWERTTFGFSIPKHNTFKK
CHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]