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The map label for this gene is ycbL [H]

Identifier: 118476036

GI number: 118476036

Start: 311116

End: 311829

Strand: Reverse

Name: ycbL [H]

Synonym: BALH_0278

Alternate gene names: 118476036

Gene position: 311829-311116 (Counterclockwise)

Preceding gene: 118476038

Following gene: 118476035

Centisome position: 5.93

GC content: 32.49

Gene sequence:

>714_bases
ATGAAAGATATACGTATCCTTATAGCAGACGATGATAAAGAAATCCGTAATTTACTAAAAATATATTTAGAACGAGAATT
ATATATGGTAGATACTGCAATTGATGGCGAAGTAGCCTTACAGTTATTTAATCAAAACAACTATAGCCTCGTTATATTAG
ATCTTATGATGCCGAAAGTAGATGGTATCGAAGTATGTAGAAAGCTTAGAGATAAAACTAACGTACCGATATTAATGCTA
ACCGCTAAAGATCACGAAGTCGATAAAATTTTAGGTTTAAGCATTGGTGCTGATGATTACATTACGAAGCCTTTCAGCAT
TCACGAAGTAGTTGCACGAGTCAAAGCTCTTATACGGCGTTTTTTAGTTCTTGGAAGTAACATTAATGTACAAGAGAAGA
CAACTTTAGCTTTTAAAGGACTAACTATCAATTTAAATACATATACAGTTCACACAAATAAAGAAGAAATCAGCTTAACC
GGAAAAGAACTAGAACTATTAAAATTCTTTACTTCAAACCCAGGACAAGTATTTACAAAAACACAGCTCTTTCGCAATGT
ATGGGACGATAATTATATAGAAGATGATAATACCGTTATGGTACATATTCGAAAACTTAGAAAGAAAATAGAAACCGATC
CTTCCAATCCAAAATTCATTCAAACTGTATGGGGAATTGGCTATAAGTTTGTAGGTGAAAAGCTTGAAGATTGA

Upstream 100 bases:

>100_bases
TTCCCTTCCCTAAAACTATTAACCTTATTTTAACAAATACTAGTATATAATTAGAGAGTTGTTGTACCATCAATGAAATC
CATTAGAAGTAGGTGAAGAT

Downstream 100 bases:

>100_bases
TAAAATCCTCTTCCTTATTTCATTACAACTTATCATTTACGGGCTTTTACATATACAAATGGATCCAAAAGTAAAAATTT
CTTTATTTATTACCCTTATC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSLVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIETDPSNPKFIQTVWGIGYKFVGEKLED

Sequences:

>Translated_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSLVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIETDPSNPKFIQTVWGIGYKFVGEKLED
>Mature_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSLVILDLMMPKVDGIEVCRKLRDKTNVPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRRFLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIETDPSNPKFIQTVWGIGYKFVGEKLED

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.5281385281385, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=38.0530973451327, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.117903930131, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=36.6666666666667, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.9307359307359, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=35.8407079646018, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=36.7256637168142, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=35.2173913043478, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=35.1931330472103, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.7719298245614, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=33.0472103004292, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=34.1880341880342, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=31.5555555555556, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=32.2033898305085, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=40.9523809523809, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27363; Mature: 27363

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSLVILDLMMPKV
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCC
DGIEVCRKLRDKTNVPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HHHHCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIETDPSNPKFIQTVWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAIDGEVALQLFNQNNYSLVILDLMMPKV
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCC
DGIEVCRKLRDKTNVPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVVARVKALIRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNINVQEKTTLAFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HHHHCCCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIETDPSNPKFIQTVWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]