Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 118475842

GI number: 118475842

Start: 76643

End: 77515

Strand: Direct

Name: pabC [H]

Synonym: BALH_0069

Alternate gene names: 118475842

Gene position: 76643-77515 (Clockwise)

Preceding gene: 118475841

Following gene: 118475843

Centisome position: 1.46

GC content: 35.4

Gene sequence:

>873_bases
ATGTTAATTTACGTAAACGGTCAGTATGTAAAAGCGAGTGAAGCGAGAATTTCGCCGTATGACCACGGTTATTTATATGG
TCTTGGAGTTTTTGAGACGTTTCGTATTTATAATGGCCATCCTTTCTTATTGGATGATCATTATGACCGTTTAATAGATG
CGCTGGATACATTGCAAATAAAATGGACAATGACAAAAGATGAAGTACTGCTTATTTTGAAGAATTTACTCATTAAGAAT
AAATTAGAGAATGCGTATGTCCGTTTTAATGTATCGGCGGGTATAGATGAAATTGGATTGCAAACGGAAATGTATGAAGA
GCCGTCTGTTATTGTTTTTATAAAACCTTTAGCAGCCCCAGGAGAGGTAGCGGAAAAAGAAGGGGTTGTTTTAAAACAAG
TTCGAAATACACCAGAGGGTGCGGCTCGTTTGAAGTCTCATCATTATTTAAATAACATTTTAGGAAAACGTGAAATTGGA
AATGTTGTGAATAAGGAAGGTATTTTTCTTACTGAAACAGGTTATGTTGCAGAGGGTATTGTTTCGAATCTCTTTTTTGT
GAAAGGTGATATTTTATATACACCTTCTCTCGAAACAGGGATTTTAAATGGTATCACTCGTGCGTTTATTATAAAAGTTG
CTGAAGAGCTAGGTATAAAAGTAAAGGAAGGTTTCTTTACAAAAGATGAATTACTTTCAGCTGATGAAGTCTTCGTAACA
AACTCGATTCAAGAAATTGTTCCGCTTAATCGTATAGAGGAACGGGATTTCCCGGGTAAAGTAGGTATGGTTACAAAAAG
ATTTATAAATCTTTATGAAATGCAGAGAGAGAAATTGTGGAGCAGAAATGAATTGCGAAGAGGAGATGTGTAG

Upstream 100 bases:

>100_bases
CGATTGAAGGTGTACAGTTCCATCCGGAATCTATTATGACTTCTCACGGGAAAGAGTTGTTGCAGAATTTCATTCGTAAA
TACAGTCCAAGTGTGACCTC

Downstream 100 bases:

>100_bases
TTTGAAGTGGGATTATGATTTGCGCTGCGGCGAATATACATTGAACTTAAATGAAAAAACGTTAATTATGGGGATTTTAA
ATGTAACACCAGATTCGTTT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MLIYVNGQYVKASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVLLILKNLLIKN
KLENAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLAAPGEVAEKEGVVLKQVRNTPEGAARLKSHHYLNNILGKREIG
NVVNKEGIFLTETGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEERDFPGKVGMVTKRFINLYEMQREKLWSRNELRRGDV

Sequences:

>Translated_290_residues
MLIYVNGQYVKASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVLLILKNLLIKN
KLENAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLAAPGEVAEKEGVVLKQVRNTPEGAARLKSHHYLNNILGKREIG
NVVNKEGIFLTETGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEERDFPGKVGMVTKRFINLYEMQREKLWSRNELRRGDV
>Mature_290_residues
MLIYVNGQYVKASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQIKWTMTKDEVLLILKNLLIKN
KLENAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLAAPGEVAEKEGVVLKQVRNTPEGAARLKSHHYLNNILGKREIG
NVVNKEGIFLTETGYVAEGIVSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVT
NSIQEIVPLNRIEERDFPGKVGMVTKRFINLYEMQREKLWSRNELRRGDV

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=294, Percent_Identity=31.9727891156463, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787338, Length=244, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 33037; Mature: 33037

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYVNGQYVKASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEEHHHEEEEEECCCEEEECCHHHHHHHHHHCEEE
KWTMTKDEVLLILKNLLIKNKLENAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLAAP
EEEECHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GEVAEKEGVVLKQVRNTPEGAARLKSHHYLNNILGKREIGNVVNKEGIFLTETGYVAEGI
CCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCHHHHH
VSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVT
HHHHEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCCCEEEC
NSIQEIVPLNRIEERDFPGKVGMVTKRFINLYEMQREKLWSRNELRRGDV
CCHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCC
>Mature Secondary Structure
MLIYVNGQYVKASEARISPYDHGYLYGLGVFETFRIYNGHPFLLDDHYDRLIDALDTLQI
CEEEEECCEEECCCCCCCCCCCCEEEEEHHHEEEEEECCCEEEECCHHHHHHHHHHCEEE
KWTMTKDEVLLILKNLLIKNKLENAYVRFNVSAGIDEIGLQTEMYEEPSVIVFIKPLAAP
EEEECHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHCCCHHHCCCCCEEEEEECCCCC
GEVAEKEGVVLKQVRNTPEGAARLKSHHYLNNILGKREIGNVVNKEGIFLTETGYVAEGI
CCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECCCHHHHH
VSNLFFVKGDILYTPSLETGILNGITRAFIIKVAEELGIKVKEGFFTKDELLSADEVFVT
HHHHEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCCCEEEC
NSIQEIVPLNRIEERDFPGKVGMVTKRFINLYEMQREKLWSRNELRRGDV
CCHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]