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The map label for this gene is pabA [H]

Identifier: 118475841

GI number: 118475841

Start: 76053

End: 76649

Strand: Direct

Name: pabA [H]

Synonym: BALH_0068

Alternate gene names: 118475841

Gene position: 76053-76649 (Clockwise)

Preceding gene: 118475840

Following gene: 118475842

Centisome position: 1.45

GC content: 40.37

Gene sequence:

>597_bases
GTGAGAGAAATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACA
AGAGCTTGTTGTTAAACGTAACGATGAAGTGACTATTTCAGATATTGAGAATATGAAACCAGACTTTTTAATGATTTCGC
CAGGCCCATGTAGTCCGAATGAGGCAGGGATTAGTATGGATGTTATTCGATACTTCGCTGGGAAGATTCCGATTTTTGGG
GTTTGTCTTGGGCACCAATCTATTGCGCAAGTGTTTGGCGGAGAGGTTGTCCGTGCAGAGCGATTAATGCATGGGAAAAC
GTCACCTATGCATCATGATGGAAAGACGATTTTTTCGGATATCCCTAATCCATTTACTGCGACGCGCTATCATTCCCTTA
TTGTTAAGAAAGAGACGTTACCTGATTGCCTAGAGGTAACATCTTGGACAGAAGAAGGGGAAATTATGGCGCTCCGTCAT
ACAACATTACCGATTGAAGGTGTACAGTTCCATCCGGAATCTATTATGACTTCTCACGGGAAAGAGTTGTTGCAGAATTT
CATTCGTAAATACAGTCCAAGTGTGACCTCATGTTAA

Upstream 100 bases:

>100_bases
GAATTGTAATTGATTCAAATCCGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTATGGCGTGCAAAAGAA
CGTAGCGAAGAAACGGTTAG

Downstream 100 bases:

>100_bases
TTTACGTAAACGGTCAGTATGTAAAAGCGAGTGAAGCGAGAATTTCGCCGTATGACCACGGTTATTTATATGGTCTTGGA
GTTTTTGAGACGTTTCGTAT

Product: para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MREMILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMDVIRYFAGKIPIFG
VCLGHQSIAQVFGGEVVRAERLMHGKTSPMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRH
TTLPIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC

Sequences:

>Translated_198_residues
MREMILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMDVIRYFAGKIPIFG
VCLGHQSIAQVFGGEVVRAERLMHGKTSPMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRH
TTLPIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC
>Mature_198_residues
MREMILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPNEAGISMDVIRYFAGKIPIFG
VCLGHQSIAQVFGGEVVRAERLMHGKTSPMHHDGKTIFSDIPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRH
TTLPIEGVQFHPESIMTSHGKELLQNFIRKYSPSVTSC

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=58.8235294117647, Blast_Score=260, Evalue=4e-71,
Organism=Escherichia coli, GI1787517, Length=199, Percent_Identity=39.6984924623116, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786215, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=49.2063492063492, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 22291; Mature: 22291

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREMILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPN
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEECCCCCCCC
EAGISMDVIRYFAGKIPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSPMHHDGKTIFSD
CCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHC
IPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTLPIEGVQFHPESIMTSHG
CCCCCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHH
KELLQNFIRKYSPSVTSC
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREMILMIDNYDSFTFNLVQFLGELGQELVVKRNDEVTISDIENMKPDFLMISPGPCSPN
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEEEECCCCCCCC
EAGISMDVIRYFAGKIPIFGVCLGHQSIAQVFGGEVVRAERLMHGKTSPMHHDGKTIFSD
CCCCHHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHC
IPNPFTATRYHSLIVKKETLPDCLEVTSWTEEGEIMALRHTTLPIEGVQFHPESIMTSHG
CCCCCHHHHHHHHEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECHHHHHHHHH
KELLQNFIRKYSPSVTSC
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]