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The map label for this gene is pabB [H]

Identifier: 118475840

GI number: 118475840

Start: 74614

End: 76056

Strand: Direct

Name: pabB [H]

Synonym: BALH_0067

Alternate gene names: 118475840

Gene position: 74614-76056 (Clockwise)

Preceding gene: 118475839

Following gene: 118475841

Centisome position: 1.42

GC content: 38.39

Gene sequence:

>1443_bases
GTGGTTAATATAAGAGGGTGGGATAAAAGAAGACGGGGTGTTGATATGCAACGAAGAAAATCTTTAGCGCTTTCTATTCC
ATATCAGTTAGATTTCTTTAAGCAATATAAATTTCTTTCTAAGGATAAACCGCAACACATTTTGTTAGAGAGTGGACGTG
GCGGTCGTTATAACGTCGTGGGATTAAACCCAGTAGCGGTAATCCGAGGGAAGGGTGAAGCGTTACATATAAGTGAAAGT
GGTAAGGAAACAATAAAGCAAGGAAACCCATTGGATTTAATGCAGGAATATATGGAGCGATGGAAAACGGATTACAATCC
GGAATACCCGCCTTTTCAAGGTGGTGCAATTGGTTACTTTAGTTATGATTGCATCCGTTATATTGAAAAACTTCCTTCTC
TTGCGGAGGATGATATTAATATACCTGATATATTCTTTTTATTATTTGATGATGTGTTTGTGTATGATCAAAAAGAAAAA
GTATTATGGATTATTACACATTATGTAGATAAGCATGAAGAGGCAAAAGAGCGATTAAATGAATGGAAGATTCTTTGGGC
GACAGAAGCGCCGGAAGTGACTATACCGTTTGCGTGCCCTGAAAAGAAAAATGAAGCAGTTGCTTTTACTGAAGAAAGCT
TTATGAAGGCGGTTGAATGTATTCAAGAATATATTGGGGCTGGTGATGTGTTCCAAGTAAACTTGTCGACAAGACAAGAA
AGAACGTTACAAACACACCCACTAGAAATATATACAAGTCTTCGTGAAATTAATCCATCTCCATATATGGGTTACTTGGA
GCTCGGGGATTTTCAAATTGTAAGTGGATCGCCAGAGTTGCTAATTAAGAAACAGGGAACTGAAGTAAGTACAAGACCAA
TTGCTGGAACGAGATCTAGAGGGGCAAATGAACAAGAGGATGAAGAATTGGCAAGGGAATTAATTGAGAATGAAAAAGAA
AGAGCAGAGCACGTCATGCTTGTGGATTTAGAACGAAATGATTTAGGACGTGTTTGTAAATATGGCACTGTAGAAGTAGA
CGAGTTTATGGTAATTGAGAAATACTCACATGTTATGCATATTGTTTCTAATGTGCGTGGTGAGGTGGAAGAAGATAAAG
ATGCTTTCGATTTAGTGAAGGCTGTATTCCCTGGAGGAACAATTACGGGTGCTCCGAAAATACGTACGATGGAAATTATT
GAAGAATTAGAACCTGTTCGCCGAGGGATTTATACAGGTTCAATCGGTTGGATTGGTTATTCTGGAGATACAGAATTGAA
TATTGTAATTAGGACACTTCTTGCTAAAGACGGAAAAGCGCATGTACAAGCAGGGGCGGGAATTGTAATTGATTCAAATC
CGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTATGGCGTGCAAAAGAACGTAGCGAAGAAACGGTTAGG
TGA

Upstream 100 bases:

>100_bases
GACTAGAAAACTTCATGTAAAATAAGAGGTAGTATTATTAATTTATTTTCACTAGCCTTCGAATATAACCCTTCTATATA
CATACCGAATGTAGCTTGAA

Downstream 100 bases:

>100_bases
GAGAAATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACAAGAG
CTTGTTGTTAAACGTAACGA

Product: aminodeoxychorismate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MVNIRGWDKRRRGVDMQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNVVGLNPVAVIRGKGEALHISES
GKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEK
VLWIITHYVDKHEEAKERLNEWKILWATEAPEVTIPFACPEKKNEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQE
RTLQTHPLEIYTSLREINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKE
RAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEII
EELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Sequences:

>Translated_480_residues
MVNIRGWDKRRRGVDMQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNVVGLNPVAVIRGKGEALHISES
GKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEK
VLWIITHYVDKHEEAKERLNEWKILWATEAPEVTIPFACPEKKNEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQE
RTLQTHPLEIYTSLREINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKE
RAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEII
EELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
>Mature_480_residues
MVNIRGWDKRRRGVDMQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNVVGLNPVAVIRGKGEALHISES
GKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEK
VLWIITHYVDKHEEAKERLNEWKILWATEAPEVTIPFACPEKKNEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQE
RTLQTHPLEIYTSLREINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKE
RAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEII
EELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=428, Percent_Identity=36.6822429906542, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI1787518, Length=366, Percent_Identity=38.5245901639344, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1786809, Length=205, Percent_Identity=28.780487804878, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87082077, Length=216, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=474, Percent_Identity=36.7088607594937, Blast_Score=299, Evalue=8e-82,
Organism=Saccharomyces cerevisiae, GI6324361, Length=402, Percent_Identity=24.8756218905473, Blast_Score=119, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 54984; Mature: 54984

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIRGWDKRRRGVDMQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNVV
CCCCCCCHHHHCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
GLNPVAVIRGKGEALHISESGKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYF
ECCCEEEEECCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEH
SYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEKVLWIITHYVDKHEEAKERLN
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEHHHCCHHHHHHHHC
EWKILWATEAPEVTIPFACPEKKNEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQE
CEEEEEECCCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
RTLQTHPLEIYTSLREINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSR
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCC
GANEQEDEELARELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMH
CCCCCHHHHHHHHHHHCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHH
IVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGY
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEE
SGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVNIRGWDKRRRGVDMQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNVV
CCCCCCCHHHHCCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEE
GLNPVAVIRGKGEALHISESGKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYF
ECCCEEEEECCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEH
SYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQKEKVLWIITHYVDKHEEAKERLN
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEHHHCCHHHHHHHHC
EWKILWATEAPEVTIPFACPEKKNEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQE
CEEEEEECCCCCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHH
RTLQTHPLEIYTSLREINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSR
HHHCCCCHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCC
GANEQEDEELARELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMH
CCCCCHHHHHHHHHHHCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHH
IVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGY
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEE
SGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]