Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 117921925

GI number: 117921925

Start: 4182368

End: 4183276

Strand: Direct

Name: adrA [H]

Synonym: Shewana3_3488

Alternate gene names: 117921925

Gene position: 4182368-4183276 (Clockwise)

Preceding gene: 117921923

Following gene: 117921928

Centisome position: 84.11

GC content: 50.5

Gene sequence:

>909_bases
ATGGTCAGTATTGAGCAAATGGCTTTAGTGCTGGACGCGCTACCCGATCCGGCGTTTATCCTGTCCCAAAGCGGCCGCTA
TGTTGCGGTGTTTGGCGGTAAAGATGCGCGTTATTACCACGACGGCAGTGGATTAGTCGGCCTTTACCTGAGCGATGTAC
TCAACGACGAAAAAACCACTTACTACCTCGGTATTATTCAGCAAGCCTTAGATAGCCGTAAATTATTGATTGAGGAATAT
GAGCTCAGTAATAAGGATGTCAAAGGCTTACCCGATGAAGGACCATCGCAACCCATCTGGTTTGAGGGGCGCATTCAGGC
GTTAGATTTTCTGGTGAATAACGAACCCGTCGTCCTCTGGGTCGCCAGTAATATTTCCAAGCGCCATAAACTGGAATTAC
AACTGCGACAGTTAAGCGATACCGACCAATTGACAGGGCTCTATAACCGCCGCCGCTTAGACCGTGATTTACAACTACTC
TTCGACACCTTTAGCCGCCACCGTATTCCGGCCTCGATCTTAGTCTTAGATCTGGACCACCTAAAGCGGATCAACGATCA
ACTGGGCCACCAAGCGGGCGATCGCGTTATCATGGCAGTCGCCGACACCTGCCAACAACAATTTCGCAAAACCGACAGCG
CCTACCGTTTTGGTGGCGATGAGTTTGTGATTGCCCTGCCCGGAGTTGACCATGACCAAGCCATAGTGTTTGCCGAATAC
CTCTGTGACTGCTGCTTTAAGGCATTGCAGCAACTCTCTGTAAAGGGATTATTTGCCACCGTCAGCATAGGTGTCGCCAG
CATAGAAGCGGGCGATAAATCCTATGAAGACACCCTAAAACGCGCCGATGCAGCGCTCTATCAAGCCAAGCGGGATGGCA
AAAACCGCGTTATCGCCAATAGTGCTTGA

Upstream 100 bases:

>100_bases
AAGCTAAATTCTTACCATAGACTGAATGGCGAATGATGACATTCTTAGCAAGTGTCAAAGCCTTGAATAAGTCAGATAAC
CTTTGTGGGGAGCTTGTTTG

Downstream 100 bases:

>100_bases
TGCCGCATCGCCCCGACAAATCACCAATAAAAAAGCGAACCTAGGTTCGCTTTTTTTATATACATCACACGCTTCGCGTT
GCGATTATTGCGCCGCTTTG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MVSIEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGLVGLYLSDVLNDEKTTYYLGIIQQALDSRKLLIEEY
ELSNKDVKGLPDEGPSQPIWFEGRIQALDFLVNNEPVVLWVASNISKRHKLELQLRQLSDTDQLTGLYNRRRLDRDLQLL
FDTFSRHRIPASILVLDLDHLKRINDQLGHQAGDRVIMAVADTCQQQFRKTDSAYRFGGDEFVIALPGVDHDQAIVFAEY
LCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKRADAALYQAKRDGKNRVIANSA

Sequences:

>Translated_302_residues
MVSIEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGLVGLYLSDVLNDEKTTYYLGIIQQALDSRKLLIEEY
ELSNKDVKGLPDEGPSQPIWFEGRIQALDFLVNNEPVVLWVASNISKRHKLELQLRQLSDTDQLTGLYNRRRLDRDLQLL
FDTFSRHRIPASILVLDLDHLKRINDQLGHQAGDRVIMAVADTCQQQFRKTDSAYRFGGDEFVIALPGVDHDQAIVFAEY
LCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKRADAALYQAKRDGKNRVIANSA
>Mature_302_residues
MVSIEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGLVGLYLSDVLNDEKTTYYLGIIQQALDSRKLLIEEY
ELSNKDVKGLPDEGPSQPIWFEGRIQALDFLVNNEPVVLWVASNISKRHKLELQLRQLSDTDQLTGLYNRRRLDRDLQLL
FDTFSRHRIPASILVLDLDHLKRINDQLGHQAGDRVIMAVADTCQQQFRKTDSAYRFGGDEFVIALPGVDHDQAIVFAEY
LCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKRADAALYQAKRDGKNRVIANSA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=180, Percent_Identity=36.6666666666667, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=39.0374331550802, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=37.0786516853933, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=35.6687898089172, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=28.4883720930233, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787802, Length=184, Percent_Identity=31.5217391304348, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=199, Percent_Identity=31.6582914572864, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788381, Length=179, Percent_Identity=27.9329608938547, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=31.4814814814815, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788085, Length=178, Percent_Identity=29.7752808988764, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=174, Percent_Identity=32.183908045977, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787541, Length=184, Percent_Identity=27.1739130434783, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081977, Length=154, Percent_Identity=29.2207792207792, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 33861; Mature: 33861

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGLVGLYLSDVLNDEKTT
CCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHCCCCHH
YYLGIIQQALDSRKLLIEEYELSNKDVKGLPDEGPSQPIWFEGRIQALDFLVNNEPVVLW
HHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHEEEEEEECCCCEEEE
VASNISKRHKLELQLRQLSDTDQLTGLYNRRRLDRDLQLLFDTFSRHRIPASILVLDLDH
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHH
LKRINDQLGHQAGDRVIMAVADTCQQQFRKTDSAYRFGGDEFVIALPGVDHDQAIVFAEY
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHHH
LCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKRADAALYQAKRDGKNRVIAN
HHHHHHHHHHHHHHHHHEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEC
SA
CC
>Mature Secondary Structure
MVSIEQMALVLDALPDPAFILSQSGRYVAVFGGKDARYYHDGSGLVGLYLSDVLNDEKTT
CCCHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCEEECCCCCHHHHHHHHHCCCCHH
YYLGIIQQALDSRKLLIEEYELSNKDVKGLPDEGPSQPIWFEGRIQALDFLVNNEPVVLW
HHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCHHEEEEEEECCCCEEEE
VASNISKRHKLELQLRQLSDTDQLTGLYNRRRLDRDLQLLFDTFSRHRIPASILVLDLDH
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHH
LKRINDQLGHQAGDRVIMAVADTCQQQFRKTDSAYRFGGDEFVIALPGVDHDQAIVFAEY
HHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCEEECCCEEEEECCCCCCCHHHHHHHH
LCDCCFKALQQLSVKGLFATVSIGVASIEAGDKSYEDTLKRADAALYQAKRDGKNRVIAN
HHHHHHHHHHHHHHHHHEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]