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The map label for this gene is lip2 [H]

Identifier: 117921899

GI number: 117921899

Start: 4151848

End: 4152837

Strand: Direct

Name: lip2 [H]

Synonym: Shewana3_3462

Alternate gene names: 117921899

Gene position: 4151848-4152837 (Clockwise)

Preceding gene: 117921898

Following gene: 117921904

Centisome position: 83.5

GC content: 53.13

Gene sequence:

>990_bases
ATGCAAGTTTCCCCACGCGGTACCGCTTCAGCAAAGCTGACGGATTTTCTTGAGTTAGCGAACCAGAATATCGCCCTCGC
GAAACAGCAAAATATTCAATACAGCCCACAGCTGCTGCGGGAAAACTTGAACAAACTCGCTGCCCTGATGAGTGCTAAGC
CTGAGGTGAGTTATATCGCCGATAAGGCATGGCAAGTTAAGGATGCGCAGCATGGCGACAGGGAAATTGGTTGCCGAGTT
TATAGCCCTGCGCCCAACAAAGCGCTGCCCGTGGTATTACATTTTCACGGCGGCGGCCATATGTGCGGCAGTGTGGAGCT
ATACGACCCTATCTGTCGTCACCTTGCCAGTATCGCTCAATGTGTGGTGATCAGTGTTGAGTATCGCCTCGCGCCCGAAC
ATCCCTATCCGGCGGGACTTGAAGACTGCGAATACGCCCTGCGCCACTATCAAAGCGTGCTGACTGAGGTGCAATACCAA
CAAGGTGTCAGCATTATGGGTGACAGTGCCGGTGGCGCGCTATGCACTAGCCTTAGCCAACGCAGCCTCAGCGACAGCAC
ACTTAACATCGCCAAACAGATCTTGGTGTATCCCAGCGTGGATTACACTATGGCGAGCGCTTCCTATCAGAGTAATGGTG
CGGGTTTCTTGCTCGAAACCCCGAGGGTGCAATGGTACTTCGAGCAATATTTTCAGGAAGTGGCTAAGGATGCCGAGCGA
GTCAAACAAGCTTCCCCCTTACATGGCGAGTTCAACGCCAAACTGCCCAGCACCTTGATATTTACCGCGGGCTGTGACCC
ACTGCGAGATGAAGGCATTGCCTATGCCAACGCCTTAACAGCAGCTGGCGTGCAGGTGCAACACCATCAATTTGAAGACA
TGATCCACGCCTATATGCTGCTGCAGGATTTGGTTACAGAAGAATGCCTTGCGACCTACCGCATGATTGCCGCGTTTTTA
GCTGAGCCCATAACCGCGACCTCTCGCTAG

Upstream 100 bases:

>100_bases
GCAGTTACTTCGCCTCGTTTGTGCTGATCACCCTATTAAGCGCCACAGTGTTTGTCGGCAGCTATTTTCTCCCCGAAACC
GGACAAGCTAAGGAGTAAGC

Downstream 100 bases:

>100_bases
CTGGCCCATTCAAACTCTCCCTCAAAGCACCTACACCCAAGATATGTTTGTAGGTGCTTATTTTTTAAGTAGCAATTAGC
GGGAGGACATCATTAAAAAA

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQVSPRGTASAKLTDFLELANQNIALAKQQNIQYSPQLLRENLNKLAALMSAKPEVSYIADKAWQVKDAQHGDREIGCRV
YSPAPNKALPVVLHFHGGGHMCGSVELYDPICRHLASIAQCVVISVEYRLAPEHPYPAGLEDCEYALRHYQSVLTEVQYQ
QGVSIMGDSAGGALCTSLSQRSLSDSTLNIAKQILVYPSVDYTMASASYQSNGAGFLLETPRVQWYFEQYFQEVAKDAER
VKQASPLHGEFNAKLPSTLIFTAGCDPLRDEGIAYANALTAAGVQVQHHQFEDMIHAYMLLQDLVTEECLATYRMIAAFL
AEPITATSR

Sequences:

>Translated_329_residues
MQVSPRGTASAKLTDFLELANQNIALAKQQNIQYSPQLLRENLNKLAALMSAKPEVSYIADKAWQVKDAQHGDREIGCRV
YSPAPNKALPVVLHFHGGGHMCGSVELYDPICRHLASIAQCVVISVEYRLAPEHPYPAGLEDCEYALRHYQSVLTEVQYQ
QGVSIMGDSAGGALCTSLSQRSLSDSTLNIAKQILVYPSVDYTMASASYQSNGAGFLLETPRVQWYFEQYFQEVAKDAER
VKQASPLHGEFNAKLPSTLIFTAGCDPLRDEGIAYANALTAAGVQVQHHQFEDMIHAYMLLQDLVTEECLATYRMIAAFL
AEPITATSR
>Mature_329_residues
MQVSPRGTASAKLTDFLELANQNIALAKQQNIQYSPQLLRENLNKLAALMSAKPEVSYIADKAWQVKDAQHGDREIGCRV
YSPAPNKALPVVLHFHGGGHMCGSVELYDPICRHLASIAQCVVISVEYRLAPEHPYPAGLEDCEYALRHYQSVLTEVQYQ
QGVSIMGDSAGGALCTSLSQRSLSDSTLNIAKQILVYPSVDYTMASASYQSNGAGFLLETPRVQWYFEQYFQEVAKDAER
VKQASPLHGEFNAKLPSTLIFTAGCDPLRDEGIAYANALTAAGVQVQHHQFEDMIHAYMLLQDLVTEECLATYRMIAAFL
AEPITATSR

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68051721, Length=325, Percent_Identity=28, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI206597554, Length=305, Percent_Identity=28.5245901639344, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI226423947, Length=333, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI68299767, Length=287, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI157041239, Length=344, Percent_Identity=24.7093023255814, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI61966717, Length=152, Percent_Identity=30.2631578947368, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786682, Length=232, Percent_Identity=27.1551724137931, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17540028, Length=201, Percent_Identity=32.8358208955224, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567059, Length=262, Percent_Identity=30.1526717557252, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71996133, Length=213, Percent_Identity=30.0469483568075, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI72001146, Length=312, Percent_Identity=25.3205128205128, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 36279; Mature: 36279

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSPRGTASAKLTDFLELANQNIALAKQQNIQYSPQLLRENLNKLAALMSAKPEVSYIA
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
DKAWQVKDAQHGDREIGCRVYSPAPNKALPVVLHFHGGGHMCGSVELYDPICRHLASIAQ
HCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
CVVISVEYRLAPEHPYPAGLEDCEYALRHYQSVLTEVQYQQGVSIMGDSAGGALCTSLSQ
HHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
RSLSDSTLNIAKQILVYPSVDYTMASASYQSNGAGFLLETPRVQWYFEQYFQEVAKDAER
HCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VKQASPLHGEFNAKLPSTLIFTAGCDPLRDEGIAYANALTAAGVQVQHHQFEDMIHAYML
HHHCCCCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LQDLVTEECLATYRMIAAFLAEPITATSR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQVSPRGTASAKLTDFLELANQNIALAKQQNIQYSPQLLRENLNKLAALMSAKPEVSYIA
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
DKAWQVKDAQHGDREIGCRVYSPAPNKALPVVLHFHGGGHMCGSVELYDPICRHLASIAQ
HCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
CVVISVEYRLAPEHPYPAGLEDCEYALRHYQSVLTEVQYQQGVSIMGDSAGGALCTSLSQ
HHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHH
RSLSDSTLNIAKQILVYPSVDYTMASASYQSNGAGFLLETPRVQWYFEQYFQEVAKDAER
HCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VKQASPLHGEFNAKLPSTLIFTAGCDPLRDEGIAYANALTAAGVQVQHHQFEDMIHAYML
HHHCCCCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
LQDLVTEECLATYRMIAAFLAEPITATSR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]