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The map label for this gene is scoA [H]

Identifier: 117921904

GI number: 117921904

Start: 4157847

End: 4158554

Strand: Direct

Name: scoA [H]

Synonym: Shewana3_3467

Alternate gene names: 117921904

Gene position: 4157847-4158554 (Clockwise)

Preceding gene: 117921899

Following gene: 117921905

Centisome position: 83.62

GC content: 51.13

Gene sequence:

>708_bases
ATGTCTGGATTGAATAAGGTGGTTAGCAGCTACGCCGATGCGTTAGCGGGACTCGAAGATGGGATGACGGTGATTGCGGG
CGGCTTTGGCCTTTGCGGTATTCCTGAAAATCTCATCAAAGAAATCAAGCACAAGGGCACCAAAAACCTGACCGTCGTCT
CCAATAACTGCGGTACCACGGAATACGGGCTTGGGATCTTACTGCTCGATAAACAAATCAAAAAAATGATCGCCTCCTAT
GTAGGCGAGAATGCTAACTTCGAGGCGCAGATGATGTCTGGCGAACTAGAGGTTGAACTCACGCCGCAGGGCACGCTGGC
GGAAAAAATGCGTGCGGCGGGCGCGGGCATTCCAGCGTTTTATACCGCAACTGGCTATGGCACTGACGTGGCAATAGGTA
AAGAAGTCAAGGAATTCAATGGTCGCCATTATATTCTTGAAGAGTCCATTACAGGCGACTTTGCCATAGTCAAAGCCTGG
AAGGCCGACACCTTCGGCAATTTAGTCTTTCGCAGAACCGCTCGTAACTTCAATCCGCTTGCCGCCACCGCGGGCAAAAT
AACCGTGGTGGAGGTGGAGGAAATTGTCGAGCCGGGTCAATTAGATCCCGATGAAATCCATACGCCCGGCATCTATGTCG
ATCGGCTTATCCAAGGCAGCTTTGAGAAACGTATTGAACAACTAACCACCCGCCCCTCCAGCAAATAG

Upstream 100 bases:

>100_bases
ATTGGCCGCGGTTTTATTTGGCACCTTAGTACCATAGGAGCGCCCGAAAAATTGGGTAATAGTAAGCGCCACACTTTCAG
CAAGCGTAAGAGAGCACTCC

Downstream 100 bases:

>100_bases
GATTTGGTTATGGCACTTTCAAGAGAACAACTCGCCCAGCGCGTCGCCCAAGAACTCAAAGATGGCTATTACGTGAATCT
CGGCATTGGTATCCCCACAC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSGLNKVVSSYADALAGLEDGMTVIAGGFGLCGIPENLIKEIKHKGTKNLTVVSNNCGTTEYGLGILLLDKQIKKMIASY
VGENANFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGYGTDVAIGKEVKEFNGRHYILEESITGDFAIVKAW
KADTFGNLVFRRTARNFNPLAATAGKITVVEVEEIVEPGQLDPDEIHTPGIYVDRLIQGSFEKRIEQLTTRPSSK

Sequences:

>Translated_235_residues
MSGLNKVVSSYADALAGLEDGMTVIAGGFGLCGIPENLIKEIKHKGTKNLTVVSNNCGTTEYGLGILLLDKQIKKMIASY
VGENANFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGYGTDVAIGKEVKEFNGRHYILEESITGDFAIVKAW
KADTFGNLVFRRTARNFNPLAATAGKITVVEVEEIVEPGQLDPDEIHTPGIYVDRLIQGSFEKRIEQLTTRPSSK
>Mature_234_residues
SGLNKVVSSYADALAGLEDGMTVIAGGFGLCGIPENLIKEIKHKGTKNLTVVSNNCGTTEYGLGILLLDKQIKKMIASYV
GENANFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAFYTATGYGTDVAIGKEVKEFNGRHYILEESITGDFAIVKAWK
ADTFGNLVFRRTARNFNPLAATAGKITVVEVEEIVEPGQLDPDEIHTPGIYVDRLIQGSFEKRIEQLTTRPSSK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=245, Percent_Identity=58.3673469387755, Blast_Score=284, Evalue=4e-77,
Organism=Homo sapiens, GI11545841, Length=241, Percent_Identity=54.356846473029, Blast_Score=245, Evalue=2e-65,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=41.8269230769231, Blast_Score=186, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=53.0864197530864, Blast_Score=261, Evalue=3e-70,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=55.3719008264463, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=55.3719008264463, Blast_Score=261, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25364; Mature: 25233

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLNKVVSSYADALAGLEDGMTVIAGGFGLCGIPENLIKEIKHKGTKNLTVVSNNCGTT
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
EYGLGILLLDKQIKKMIASYVGENANFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAF
HHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCCEE
YTATGYGTDVAIGKEVKEFNGRHYILEESITGDFAIVKAWKADTFGNLVFRRTARNFNPL
EEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC
AATAGKITVVEVEEIVEPGQLDPDEIHTPGIYVDRLIQGSFEKRIEQLTTRPSSK
CCCCCCEEEEEHHHHCCCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SGLNKVVSSYADALAGLEDGMTVIAGGFGLCGIPENLIKEIKHKGTKNLTVVSNNCGTT
CHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
EYGLGILLLDKQIKKMIASYVGENANFEAQMMSGELEVELTPQGTLAEKMRAAGAGIPAF
HHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCCEE
YTATGYGTDVAIGKEVKEFNGRHYILEESITGDFAIVKAWKADTFGNLVFRRTARNFNPL
EEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCC
AATAGKITVVEVEEIVEPGQLDPDEIHTPGIYVDRLIQGSFEKRIEQLTTRPSSK
CCCCCCEEEEEHHHHCCCCCCCHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]