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The map label for this gene is speE [H]

Identifier: 117921761

GI number: 117921761

Start: 3983936

End: 3984679

Strand: Direct

Name: speE [H]

Synonym: Shewana3_3323

Alternate gene names: 117921761

Gene position: 3983936-3984679 (Clockwise)

Preceding gene: 117921758

Following gene: 117921762

Centisome position: 80.12

GC content: 51.48

Gene sequence:

>744_bases
ATGGCCGACGCCACTTTGCTACACGAAACCCAAGATGCCCTAGGACCGATCCGCGTGCTCGACTATGGTGATACCCGCGT
GCTGTCCTTTGGCGACAACGATGAGCAGAGCAAAATTCTTAAAACCGCCCCGCACATCCCACAACATACCTATGTGCAAG
GCATGCTACTGGTGTTGTTATTTTGCCAACCGAAAAGCGCCATCGTACTCGGCCTTGGCGGCGGCGCCCTCATTCATGCC
CTGCGCCGCTTCGATGCCGCAATTAAACTTACTGCAGTTGAGCTTCGCCCAGCAGTGATTGAACTTGCCAAACGTTACTT
TCAATTACCGATTGGCAAAAAGCTTAATCTAATCAACCAAGATGCCGTCGCTTTTATGGCATCGGCCGAGCATAAAAAGG
TCGATGTGATTTTTGCCGATATCTACAGCGCTAAAGGGGTCGACACTGGGCAACTCTCGCCCACTTTTCTTCAGCAGTGC
ACACAACTGATTAAACCCAACGGTTATTTAGTGCTGAATTGCTGGAAGGAACACAGCCAAAATCGCGAGTTGCTCGCCGA
TCTGCAGCACCATTTTGCCCACGTGCATGCCTGCCTCACCAGCGGGGGCAACTGGGTGATTTTTGCCAGCCAAACACCAC
AATCTTTGAGCGCGTCGGCGCTGAAAAGTCAGGCGCAAACCCTGTCACAACAACTAGATTTTGCCCTTGAACGTTCACTG
ACTCGCTTTGGCCCTTGGATTTAA

Upstream 100 bases:

>100_bases
AATAGCCACTTAAAAAACGAAACCAGCTGAATTCTAACTTTTTTGCACCAGCAGTTATAGAGTCCCAAATCAGCCCAACG
CAAATAGAGTAATAAGTACT

Downstream 100 bases:

>100_bases
GATTAATCTCAGTCAAATGGCTTAAATTAGTTAACCCTAAGACTCAGCTTTGCTATGCTTCTCACTCCCTATTGATATGA
GCTGTCACCATGAAAAATAA

Product: spermine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MADATLLHETQDALGPIRVLDYGDTRVLSFGDNDEQSKILKTAPHIPQHTYVQGMLLVLLFCQPKSAIVLGLGGGALIHA
LRRFDAAIKLTAVELRPAVIELAKRYFQLPIGKKLNLINQDAVAFMASAEHKKVDVIFADIYSAKGVDTGQLSPTFLQQC
TQLIKPNGYLVLNCWKEHSQNRELLADLQHHFAHVHACLTSGGNWVIFASQTPQSLSASALKSQAQTLSQQLDFALERSL
TRFGPWI

Sequences:

>Translated_247_residues
MADATLLHETQDALGPIRVLDYGDTRVLSFGDNDEQSKILKTAPHIPQHTYVQGMLLVLLFCQPKSAIVLGLGGGALIHA
LRRFDAAIKLTAVELRPAVIELAKRYFQLPIGKKLNLINQDAVAFMASAEHKKVDVIFADIYSAKGVDTGQLSPTFLQQC
TQLIKPNGYLVLNCWKEHSQNRELLADLQHHFAHVHACLTSGGNWVIFASQTPQSLSASALKSQAQTLSQQLDFALERSL
TRFGPWI
>Mature_246_residues
ADATLLHETQDALGPIRVLDYGDTRVLSFGDNDEQSKILKTAPHIPQHTYVQGMLLVLLFCQPKSAIVLGLGGGALIHAL
RRFDAAIKLTAVELRPAVIELAKRYFQLPIGKKLNLINQDAVAFMASAEHKKVDVIFADIYSAKGVDTGQLSPTFLQQCT
QLIKPNGYLVLNCWKEHSQNRELLADLQHHFAHVHACLTSGGNWVIFASQTPQSLSASALKSQAQTLSQQLDFALERSLT
RFGPWI

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 27252; Mature: 27121

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADATLLHETQDALGPIRVLDYGDTRVLSFGDNDEQSKILKTAPHIPQHTYVQGMLLVLL
CCCCHHHHHHHHHCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
FCQPKSAIVLGLGGGALIHALRRFDAAIKLTAVELRPAVIELAKRYFQLPIGKKLNLINQ
HCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCH
DAVAFMASAEHKKVDVIFADIYSAKGVDTGQLSPTFLQQCTQLIKPNGYLVLNCWKEHSQ
HHHHHHHCCCCCEEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCC
NRELLADLQHHFAHVHACLTSGGNWVIFASQTPQSLSASALKSQAQTLSQQLDFALERSL
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRFGPWI
HHHCCCC
>Mature Secondary Structure 
ADATLLHETQDALGPIRVLDYGDTRVLSFGDNDEQSKILKTAPHIPQHTYVQGMLLVLL
CCCHHHHHHHHHCCCEEEEECCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
FCQPKSAIVLGLGGGALIHALRRFDAAIKLTAVELRPAVIELAKRYFQLPIGKKLNLINQ
HCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCH
DAVAFMASAEHKKVDVIFADIYSAKGVDTGQLSPTFLQQCTQLIKPNGYLVLNCWKEHSQ
HHHHHHHCCCCCEEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCC
NRELLADLQHHFAHVHACLTSGGNWVIFASQTPQSLSASALKSQAQTLSQQLDFALERSL
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TRFGPWI
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]