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The map label for this gene is map [H]

Identifier: 117921668

GI number: 117921668

Start: 3873280

End: 3874062

Strand: Direct

Name: map [H]

Synonym: Shewana3_3230

Alternate gene names: 117921668

Gene position: 3873280-3874062 (Clockwise)

Preceding gene: 117921667

Following gene: 117921669

Centisome position: 77.9

GC content: 47.13

Gene sequence:

>783_bases
ATGAATAATCAGGTGAAGATAAAATCTGCCGAAGAAATTGCACTGATGCGCCGCGCGGGGCAATTATTAGCTCAAGTATT
TCAAATGCTTGATACCTATGTCCGCCCCGGCATCAGCACCATGGATATCAACGATGCGGTCGAAGCCTTTATTGTCAATG
AGCTAAAATCGCGTCCCGCGAGTAAAGGTCAGTATGGCTATCAATATGTGCTGAATTCGTCTATTAACGAGGTGGTCTGC
CATGGTGTGCCCTCGCCGAATGAGGTCATCAAAAGCAAAGATATCATTAACTTAGATATTACCCTCGAGAAAGACGGCTA
TATTGCCGACTCCAGTAAAATGTATGTGATGCCACAGGCACCCGCCGAAGCTAAGAAACTGGCAGATGTTACCTATCTTG
CCATGTGGCAAGGGATCAAACAGGTAAAACCTGGGGCCACATTGGGCGATATCGGTCATGCGATTCAACAATATGCCCAA
TCCTTTGGCTATAGCATTGTCAGAGATTACTGTGGCCATGGGATAGGTCAAGAAATGCATGAAGAGCCACAAGTCCTTCA
CTATGGAAAGCCGAATCAAGGCCTTAAGCTCAAAGCGGGCATGGTATTTACCATTGAGCCCATGGTGAATCAGGGCACTG
AAAAGATAAAGCTCAAAAAAGATGGTTGGACGGTTGTCACCCGCGATAAAAAACTCTCGGCGCAATCGGAACATACGATA
CTTGTCACCCCAACGGGATACGAAGTGCTCACCCTACGCCACGATGAGCAATCTCCCCGCTAA

Upstream 100 bases:

>100_bases
GAGTTGCATCCACAGCTCTCCTTTAATCAGTTAGTCGCCGATTTAATGAAATCTGCGGACGTGAACCTAGCCAACGTGAC
CCAAGTAAAGGAAATGGCCG

Downstream 100 bases:

>100_bases
TTTCGACGCTAACCCTCGCTTTTTCATCTCAAATTCAGGTGTGCTGTAGTAAATTTGCACTGCAGTTCACCGCCCTTCAT
TAGAGTAAAAATTCTATTTT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNNQVKIKSAEEIALMRRAGQLLAQVFQMLDTYVRPGISTMDINDAVEAFIVNELKSRPASKGQYGYQYVLNSSINEVVC
HGVPSPNEVIKSKDIINLDITLEKDGYIADSSKMYVMPQAPAEAKKLADVTYLAMWQGIKQVKPGATLGDIGHAIQQYAQ
SFGYSIVRDYCGHGIGQEMHEEPQVLHYGKPNQGLKLKAGMVFTIEPMVNQGTEKIKLKKDGWTVVTRDKKLSAQSEHTI
LVTPTGYEVLTLRHDEQSPR

Sequences:

>Translated_260_residues
MNNQVKIKSAEEIALMRRAGQLLAQVFQMLDTYVRPGISTMDINDAVEAFIVNELKSRPASKGQYGYQYVLNSSINEVVC
HGVPSPNEVIKSKDIINLDITLEKDGYIADSSKMYVMPQAPAEAKKLADVTYLAMWQGIKQVKPGATLGDIGHAIQQYAQ
SFGYSIVRDYCGHGIGQEMHEEPQVLHYGKPNQGLKLKAGMVFTIEPMVNQGTEKIKLKKDGWTVVTRDKKLSAQSEHTI
LVTPTGYEVLTLRHDEQSPR
>Mature_260_residues
MNNQVKIKSAEEIALMRRAGQLLAQVFQMLDTYVRPGISTMDINDAVEAFIVNELKSRPASKGQYGYQYVLNSSINEVVC
HGVPSPNEVIKSKDIINLDITLEKDGYIADSSKMYVMPQAPAEAKKLADVTYLAMWQGIKQVKPGATLGDIGHAIQQYAQ
SFGYSIVRDYCGHGIGQEMHEEPQVLHYGKPNQGLKLKAGMVFTIEPMVNQGTEKIKLKKDGWTVVTRDKKLSAQSEHTI
LVTPTGYEVLTLRHDEQSPR

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=39.922480620155, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=30.5220883534137, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=47.4509803921569, Blast_Score=261, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=38.2470119521912, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323273, Length=261, Percent_Identity=40.2298850574713, Blast_Score=184, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21355531, Length=253, Percent_Identity=37.1541501976285, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24583427, Length=249, Percent_Identity=34.136546184739, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28955; Mature: 28955

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQVKIKSAEEIALMRRAGQLLAQVFQMLDTYVRPGISTMDINDAVEAFIVNELKSRPA
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCC
SKGQYGYQYVLNSSINEVVCHGVPSPNEVIKSKDIINLDITLEKDGYIADSSKMYVMPQA
CCCCCCCCEEECCCHHHHEECCCCCHHHHHCCCCEEEEEEEECCCCEEECCCCEEEEECC
PAEAKKLADVTYLAMWQGIKQVKPGATLGDIGHAIQQYAQSFGYSIVRDYCGHGIGQEMH
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHH
EEPQVLHYGKPNQGLKLKAGMVFTIEPMVNQGTEKIKLKKDGWTVVTRDKKLSAQSEHTI
CCCCEEECCCCCCCEEEECCEEEEECHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCEE
LVTPTGYEVLTLRHDEQSPR
EEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNNQVKIKSAEEIALMRRAGQLLAQVFQMLDTYVRPGISTMDINDAVEAFIVNELKSRPA
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCC
SKGQYGYQYVLNSSINEVVCHGVPSPNEVIKSKDIINLDITLEKDGYIADSSKMYVMPQA
CCCCCCCCEEECCCHHHHEECCCCCHHHHHCCCCEEEEEEEECCCCEEECCCCEEEEECC
PAEAKKLADVTYLAMWQGIKQVKPGATLGDIGHAIQQYAQSFGYSIVRDYCGHGIGQEMH
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHH
EEPQVLHYGKPNQGLKLKAGMVFTIEPMVNQGTEKIKLKKDGWTVVTRDKKLSAQSEHTI
CCCCEEECCCCCCCEEEECCEEEEECHHHCCCCCEEEEECCCCEEEEECCCCCCCCCCEE
LVTPTGYEVLTLRHDEQSPR
EEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]