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The map label for this gene is apaH [H]

Identifier: 117921649

GI number: 117921649

Start: 3854914

End: 3855738

Strand: Direct

Name: apaH [H]

Synonym: Shewana3_3211

Alternate gene names: 117921649

Gene position: 3854914-3855738 (Clockwise)

Preceding gene: 117921648

Following gene: 117921650

Centisome position: 77.53

GC content: 48.36

Gene sequence:

>825_bases
GTGGCCCATTATTTTGTTGGTGATGTCCAAGGCTGTTTTGCCGAACTTCAACGATTACTTGCTAAAGTCGACTTTAATCC
ATCCTGCGATGAACTCTGGGCGGTGGGCGATCTGGTCGCCAGAGGCCCAGATTCACTAGCCACATTGCGCTATTTTCAAT
CCTTAGGCGATGCGGGCAAAACCGTCCTAGGTAATCACGATCTGCATTTGCTCGCCCTGCACGGCAAACTCAAGCGGGAT
AAACCCAGCGATAACTTAACGCCGCTGTTAAATGCGCCCGATATTGCCAGTTTAATCGATTGGCTGAGACAACAGCCGTT
GATGCGGGAATTACCTGAGCATAAGATCATCATGACCCACGCTGGTGTGCCGCCACAGTGGTCATTAGAGGTGTTAAGGC
AAGAGTCGCAACTTGTCAGCCAAGCCCTCAAGCAGAGTGATTATCTCGACGCACTAATAAGCCAAATGTATAGCGATACC
GCCGAGCGGTGGGAGCCCAGCGCTATAGGGATCAATCGCCTGCGTTTTTGTATTAACGCCTTGACCAGGATGCGTTATCT
GTATGTTGATGGTCATTTAGACTTTGACTGCAAACAACCGCCAGAGGATTGCACTAATCCACAGCTACGGCCTTGGTTTG
AATTTACCTCTGCGTTACGCCAGAGTCACACTTTAGTGTTTGGACATTGGGCGGCATTGATGGGTAAAGTCAACGACCCT
AAGCTAAAAGCACTAGACACAGGCTGTTGCTGGGGGGAATATCTAACCCTATGGCATCTTGAAAAAGACCAAAAAATTAC
CCAAAAAAGGTTAAAAAAGGGTTAA

Upstream 100 bases:

>100_bases
TATGGTCAGCGAATCAGGCGAGCACTTTAAGGCAACGATTAAGCCCTTCCGCTTAGCACTCCCCGGTTTATTACATTGAT
TTAATTATAGAAAGGATATT

Downstream 100 bases:

>100_bases
ACTAAGCCCGAGAGTGGTCGATATACGACAGTACCCTATGCCCTGAATTTAATAATCTTTTCATTCGGAATAATATAATA
ATAACCGGAGTATCCTATGA

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MAHYFVGDVQGCFAELQRLLAKVDFNPSCDELWAVGDLVARGPDSLATLRYFQSLGDAGKTVLGNHDLHLLALHGKLKRD
KPSDNLTPLLNAPDIASLIDWLRQQPLMRELPEHKIIMTHAGVPPQWSLEVLRQESQLVSQALKQSDYLDALISQMYSDT
AERWEPSAIGINRLRFCINALTRMRYLYVDGHLDFDCKQPPEDCTNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDP
KLKALDTGCCWGEYLTLWHLEKDQKITQKRLKKG

Sequences:

>Translated_274_residues
MAHYFVGDVQGCFAELQRLLAKVDFNPSCDELWAVGDLVARGPDSLATLRYFQSLGDAGKTVLGNHDLHLLALHGKLKRD
KPSDNLTPLLNAPDIASLIDWLRQQPLMRELPEHKIIMTHAGVPPQWSLEVLRQESQLVSQALKQSDYLDALISQMYSDT
AERWEPSAIGINRLRFCINALTRMRYLYVDGHLDFDCKQPPEDCTNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDP
KLKALDTGCCWGEYLTLWHLEKDQKITQKRLKKG
>Mature_273_residues
AHYFVGDVQGCFAELQRLLAKVDFNPSCDELWAVGDLVARGPDSLATLRYFQSLGDAGKTVLGNHDLHLLALHGKLKRDK
PSDNLTPLLNAPDIASLIDWLRQQPLMRELPEHKIIMTHAGVPPQWSLEVLRQESQLVSQALKQSDYLDALISQMYSDTA
ERWEPSAIGINRLRFCINALTRMRYLYVDGHLDFDCKQPPEDCTNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDPK
LKALDTGCCWGEYLTLWHLEKDQKITQKRLKKG

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=268, Percent_Identity=48.134328358209, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31249; Mature: 31118

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHYFVGDVQGCFAELQRLLAKVDFNPSCDELWAVGDLVARGPDSLATLRYFQSLGDAGK
CCCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TVLGNHDLHLLALHGKLKRDKPSDNLTPLLNAPDIASLIDWLRQQPLMRELPEHKIIMTH
EEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEE
AGVPPQWSLEVLRQESQLVSQALKQSDYLDALISQMYSDTAERWEPSAIGINRLRFCINA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LTRMRYLYVDGHLDFDCKQPPEDCTNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDP
HHHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
KLKALDTGCCWGEYLTLWHLEKDQKITQKRLKKG
CHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AHYFVGDVQGCFAELQRLLAKVDFNPSCDELWAVGDLVARGPDSLATLRYFQSLGDAGK
CCEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TVLGNHDLHLLALHGKLKRDKPSDNLTPLLNAPDIASLIDWLRQQPLMRELPEHKIIMTH
EEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEEEE
AGVPPQWSLEVLRQESQLVSQALKQSDYLDALISQMYSDTAERWEPSAIGINRLRFCINA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LTRMRYLYVDGHLDFDCKQPPEDCTNPQLRPWFEFTSALRQSHTLVFGHWAALMGKVNDP
HHHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
KLKALDTGCCWGEYLTLWHLEKDQKITQKRLKKG
CHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]