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The map label for this gene is hlyB [H]

Identifier: 117921650

GI number: 117921650

Start: 3855835

End: 3857856

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_3212

Alternate gene names: 117921650

Gene position: 3855835-3857856 (Clockwise)

Preceding gene: 117921649

Following gene: 117921658

Centisome position: 77.55

GC content: 49.65

Gene sequence:

>2022_bases
ATGAAAGTTAATGTAGCCACCCGAGTCATTGGCGGGTTTAGTGTTGTTACACTTTTACTTGTGTTGTTAGGATTTACCTC
GTACCTGACGAACATTAGCCTCAAAGATAGTTCGGCCATGATGCAAGAGTTAAGCTTGCCAGCCCTAAAGGCGACCAACC
ACTTAACCGAAACCCTGAGTGAACAACAGCGCCAAGTGCTGATCGCCTATCACGCACCAAAGTCCTCGAACATTCCCGAT
ATCCGTAAAGTCTTTAACGACCACGGCACCCAGTTTAAAAACGAGATCAGCAATCTGACGCAATTGGTTCAAGGGCAAGC
CAATCTTTCTGCATTGATCTCGCAACTGGATGGTAGCTTCTCGACCTTCGAGCGCGATAGTCTCGCCATGCTCACTGAAC
GTGAAGCCGCCCTCAGCAAACAAGAGCAGCTAATCGGCTTAAAAAAGAAACTTGAAAATGCTGCCGATGACGCCTCGTCA
GTTTTGCTCGATATTATCGATTTAGAAAACAGCCAAAACCCCGATGCTCAGAGTATCGCGGCCTCTGCCAGCGCTATCGA
TACCAGCATGGGTAATATCATCACTACCATTGCCGATTTAGTGACTAATGAAGAAATGAGTAAACATGAACTCATTTCCA
AAGAGCTCGACTACATCCTGAGTGAGACCAAGAACAAACTCGAATACGTGAATCGTCATGCGCAGGACATAATTGATGCT
GACACCTTAAAATCCGTCAATGAAGACACTAAAAAGGTACTCGCGTTGCTCGAAGGCCCTGACTCTATGGTGCTATTGAA
AGCGACCCAATTGAATCATGCCAAGAGTGCCATGAATCAATTGGCGACCATTGAGAAAGATGTCAAAGTCATCGATCGCA
ATATGGAAGATGTGAGCAATAACATCGAGTCTGTGGCGGCCAATATGAGCCAAGAAACCATAGCCAAGATTGATGCCGCC
AGTATCCGCACTATTATTGTGGTGCTAATCGCCATTGTCGCCGCGGTTATCATCAGCTTTGCCGTTGTGGCACCGTTAAA
GCGCTCTCTCTATCAAGTCAATAACGCGCTGAATGTATTAGCTTCAGGCAACTTAACCCACAAATTAGATGATTCTGGCC
ATGATGAATTTGCCGAGCTTGCGAAGAACTGTAACCGTTTAGTCGATAGCTTACGCGGCTTAATCGTCGGTATTTTGGAC
CGTTCTAACCAGTTAGCCGCAGCAGCGGAACAAACGTCGGCTATCACGGCGCAAACCACCTCAGGTATCCAAGAGCAAAA
GAGCCAGGTCGACCAAGTCGCAACCGCAACCACAGAATTAAGCTCGAGTGCACAACAAGTATCGATGAGCGCCGATGACG
CTCTGGCGCAGATCAAGCAGGCCGATCAAGAAGCCAAACATATGCGCACGATTGCCGAAGAGAACAAGCGCACCATTTTA
GCCCTAGCAGACGAAGTCGCTAAGGCTGGCCAAGTGATCAACAAGGTGCAATCGGATAGCGCTTCTATCGGCTCAATTCT
CGATGTGATCCGTGGCATTGCCGAGCAGACTAACCTACTGGCACTAAACGCAGCTATCGAAGCGGCACGCGCCGGTGAGC
AAGGTCGCGGCTTTGCGGTAGTGGCCGATGAAGTACGCAGCCTGGCCTCACGAACTCAAGTCTCGACCCGCGAGATCCAG
CAAATGATCGAAGTGCTGCAACAGGGCGCGCAGCAAGCCGTAGCAGCCATGGATATGGGCCGTGCCCAGGCCAATGCCTG
TGTCGATAAGACAGAGCAAGCTAACCTCGCGCTAGAGACCATCAGCCAATCTGTACATAAAGCCTATGATGCGGGCACGC
ACATTGCCCATGCCGCGCAGGAGCAGAATGTGGTTAGTCAGCAAGTGTCTGAGAAACTTGAGCATATCGCAGCAATTTCG
GAAGAAACCGCGATTGGCGCCGATCAAACCGCGCAATCGAGCCATCAAGTGGCTAAACTCGCCGAAGAGCTGCAAGCTTC
TGTCGGTGAATTTAGAGTGTAA

Upstream 100 bases:

>100_bases
TTAAACTAAGCCCGAGAGTGGTCGATATACGACAGTACCCTATGCCCTGAATTTAATAATCTTTTCATTCGGAATAATAT
AATAATAACCGGAGTATCCT

Downstream 100 bases:

>100_bases
GCAAACGCTCAAGTATGAACAGGGTCGCAATTGCGGCCCTTTTCTTTGGATTGTGATTGTGATTGTGCTTGTGCTTTCGC
TTGGCTTTTAGGCTTTTAGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MKVNVATRVIGGFSVVTLLLVLLGFTSYLTNISLKDSSAMMQELSLPALKATNHLTETLSEQQRQVLIAYHAPKSSNIPD
IRKVFNDHGTQFKNEISNLTQLVQGQANLSALISQLDGSFSTFERDSLAMLTEREAALSKQEQLIGLKKKLENAADDASS
VLLDIIDLENSQNPDAQSIAASASAIDTSMGNIITTIADLVTNEEMSKHELISKELDYILSETKNKLEYVNRHAQDIIDA
DTLKSVNEDTKKVLALLEGPDSMVLLKATQLNHAKSAMNQLATIEKDVKVIDRNMEDVSNNIESVAANMSQETIAKIDAA
SIRTIIVVLIAIVAAVIISFAVVAPLKRSLYQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRGLIVGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSMSADDALAQIKQADQEAKHMRTIAEENKRTIL
ALADEVAKAGQVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAQQAVAAMDMGRAQANACVDKTEQANLALETISQSVHKAYDAGTHIAHAAQEQNVVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV

Sequences:

>Translated_673_residues
MKVNVATRVIGGFSVVTLLLVLLGFTSYLTNISLKDSSAMMQELSLPALKATNHLTETLSEQQRQVLIAYHAPKSSNIPD
IRKVFNDHGTQFKNEISNLTQLVQGQANLSALISQLDGSFSTFERDSLAMLTEREAALSKQEQLIGLKKKLENAADDASS
VLLDIIDLENSQNPDAQSIAASASAIDTSMGNIITTIADLVTNEEMSKHELISKELDYILSETKNKLEYVNRHAQDIIDA
DTLKSVNEDTKKVLALLEGPDSMVLLKATQLNHAKSAMNQLATIEKDVKVIDRNMEDVSNNIESVAANMSQETIAKIDAA
SIRTIIVVLIAIVAAVIISFAVVAPLKRSLYQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRGLIVGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSMSADDALAQIKQADQEAKHMRTIAEENKRTIL
ALADEVAKAGQVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAQQAVAAMDMGRAQANACVDKTEQANLALETISQSVHKAYDAGTHIAHAAQEQNVVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV
>Mature_673_residues
MKVNVATRVIGGFSVVTLLLVLLGFTSYLTNISLKDSSAMMQELSLPALKATNHLTETLSEQQRQVLIAYHAPKSSNIPD
IRKVFNDHGTQFKNEISNLTQLVQGQANLSALISQLDGSFSTFERDSLAMLTEREAALSKQEQLIGLKKKLENAADDASS
VLLDIIDLENSQNPDAQSIAASASAIDTSMGNIITTIADLVTNEEMSKHELISKELDYILSETKNKLEYVNRHAQDIIDA
DTLKSVNEDTKKVLALLEGPDSMVLLKATQLNHAKSAMNQLATIEKDVKVIDRNMEDVSNNIESVAANMSQETIAKIDAA
SIRTIIVVLIAIVAAVIISFAVVAPLKRSLYQVNNALNVLASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRGLIVGILD
RSNQLAAAAEQTSAITAQTTSGIQEQKSQVDQVATATTELSSSAQQVSMSADDALAQIKQADQEAKHMRTIAEENKRTIL
ALADEVAKAGQVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASRTQVSTREIQ
QMIEVLQQGAQQAVAAMDMGRAQANACVDKTEQANLALETISQSVHKAYDAGTHIAHAAQEQNVVSQQVSEKLEHIAAIS
EETAIGADQTAQSSHQVAKLAEELQASVGEFRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=30.2777777777778, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI2367378, Length=301, Percent_Identity=29.9003322259136, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788195, Length=285, Percent_Identity=31.9298245614035, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=27.7142857142857, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1789453, Length=340, Percent_Identity=29.7058823529412, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72298; Mature: 72298

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNVATRVIGGFSVVTLLLVLLGFTSYLTNISLKDSSAMMQELSLPALKATNHLTETLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
EQQRQVLIAYHAPKSSNIPDIRKVFNDHGTQFKNEISNLTQLVQGQANLSALISQLDGSF
HHHHEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCH
STFERDSLAMLTEREAALSKQEQLIGLKKKLENAADDASSVLLDIIDLENSQNPDAQSIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHH
ASASAIDTSMGNIITTIADLVTNEEMSKHELISKELDYILSETKNKLEYVNRHAQDIIDA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DTLKSVNEDTKKVLALLEGPDSMVLLKATQLNHAKSAMNQLATIEKDVKVIDRNMEDVSN
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NIESVAANMSQETIAKIDAASIRTIIVVLIAIVAAVIISFAVVAPLKRSLYQVNNALNVL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRGLIVGILDRSNQLAAAAEQTSAITAQTT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SGIQEQKSQVDQVATATTELSSSAQQVSMSADDALAQIKQADQEAKHMRTIAEENKRTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALADEVAKAGQVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VADEVRSLASRTQVSTREIQQMIEVLQQGAQQAVAAMDMGRAQANACVDKTEQANLALET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ISQSVHKAYDAGTHIAHAAQEQNVVSQQVSEKLEHIAAISEETAIGADQTAQSSHQVAKL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AEELQASVGEFRV
HHHHHHHHHCCCC
>Mature Secondary Structure
MKVNVATRVIGGFSVVTLLLVLLGFTSYLTNISLKDSSAMMQELSLPALKATNHLTETLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
EQQRQVLIAYHAPKSSNIPDIRKVFNDHGTQFKNEISNLTQLVQGQANLSALISQLDGSF
HHHHEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCH
STFERDSLAMLTEREAALSKQEQLIGLKKKLENAADDASSVLLDIIDLENSQNPDAQSIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCHHHHH
ASASAIDTSMGNIITTIADLVTNEEMSKHELISKELDYILSETKNKLEYVNRHAQDIIDA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DTLKSVNEDTKKVLALLEGPDSMVLLKATQLNHAKSAMNQLATIEKDVKVIDRNMEDVSN
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NIESVAANMSQETIAKIDAASIRTIIVVLIAIVAAVIISFAVVAPLKRSLYQVNNALNVL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGNLTHKLDDSGHDEFAELAKNCNRLVDSLRGLIVGILDRSNQLAAAAEQTSAITAQTT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SGIQEQKSQVDQVATATTELSSSAQQVSMSADDALAQIKQADQEAKHMRTIAEENKRTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALADEVAKAGQVINKVQSDSASIGSILDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
VADEVRSLASRTQVSTREIQQMIEVLQQGAQQAVAAMDMGRAQANACVDKTEQANLALET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ISQSVHKAYDAGTHIAHAAQEQNVVSQQVSEKLEHIAAISEETAIGADQTAQSSHQVAKL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
AEELQASVGEFRV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]