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The map label for this gene is yiaV [H]

Identifier: 117921631

GI number: 117921631

Start: 3831240

End: 3832385

Strand: Reverse

Name: yiaV [H]

Synonym: Shewana3_3193

Alternate gene names: 117921631

Gene position: 3832385-3831240 (Counterclockwise)

Preceding gene: 117921632

Following gene: 117921626

Centisome position: 77.08

GC content: 51.66

Gene sequence:

>1146_bases
ATGGATTTACTACTGATATTAACCTACGCCTCGATCTGCATTGTGATTTTTAAAGTGTTTAAGATCCCAATGAATAAATG
GACAGTGCCGACCGCCGTATTAGGAGGCGTAGTGTTGATTGGGGCGCTGCTACTTATCATGAACTACAACCATCCCTATT
CCCGTTTCGCACGGGAATACTATGTCACTATCCCGATTACACCTGCGGTAAAAGGTTTAGTGATTTCGGTGGAAGCTAAG
CCAAATACGCCGATGAAACAAGGGGATGTGCTATTTCGAATCGACCCAACACCCTTTGAGGCCGTGGTAAAACGTAAAAA
AGCGGCGTTGTTAGCGGCGGAGCAGGAAGTGCCACAACTTGCGGCCGCTTGGGAGGCAGCCAAGGCGAATGTGGCCAGAG
TGGCTGCCGACAGGGAACGCAATAAATCGGCCTATGATCGCTATGAGCAAGGCCATCGTAAAGGTGGGGCAAACTCTCCC
TTCACTGCGCTGGAATTAGATAATCGACGCCAACTGTTTTTTGCCTCAGAGGCTCAGCTAACGGCTGCGCAGGCCGAAGA
GTTACGCGCACGTCTTGCCTATGAGTCCAATGTGGATGGGGTAAATTCGAAGGTCGCTGGGCTTCAGGGGGATCTTGAAA
GCGCGCTCTATAATCTCGAGCAAACCGTAGTACGGGCACCCGCCGATGGTATTGTTACCCAAATGGCGCTGCGCCCAGGT
GCAATGGCGGTGCCTTTACCTTTACGGCCAGTGATGAGTTTTATTCCCGATGAGCAGCGTTATTTTGCTGGCGCATTCTG
GCAAAACTCCCTGCTGCGATTACAGGAAGGGGATGAGGCAGAGGTGGTATTAGATGCGGCGCCCGGACAAGTGTTTAAGG
GCAAAGTCGCTAAGGTACTCCCCGCGATGGCCGAGGGGGAGATTCAGATGAATGGTACGCTGCAATCGTCTAATCAATTG
TTCCAAAGTGGCCGGGTTATCGTATTAATCGATATTGAAGATGATGCGATACGCCGTCAATTCCCGGCGGGCGTTGCGGG
ACAAGTGGCTGTGTACACTGAACATTTCCATCATGTGGCCGTGATGCGCAAAGTGCTGCTGCGGATGCAGGGCTGGCTAA
ACTATCTGTTCTTCGATGGGCACTAG

Upstream 100 bases:

>100_bases
CAACTGGAATCGACAGCCAAGCCTGCGGTGGTGAAGCAATCCGAGGCAATACCCACAGAAGCCAGTGTGACCGAAACTAG
CCAAAAAGCCGAGGTGTAAC

Downstream 100 bases:

>100_bases
TGGAGTTTTACGCTAACGACTTCGCTTGGAGCTGGTGTTAAGCTGCCTAAGAGTGAATAAAAAGCGCTGACAATTTTGTC
AGCGCTTTTTTGTTATGTGT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDLLLILTYASICIVIFKVFKIPMNKWTVPTAVLGGVVLIGALLLIMNYNHPYSRFAREYYVTIPITPAVKGLVISVEAK
PNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQLAAAWEAAKANVARVAADRERNKSAYDRYEQGHRKGGANSP
FTALELDNRRQLFFASEAQLTAAQAEELRARLAYESNVDGVNSKVAGLQGDLESALYNLEQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLQEGDEAEVVLDAAPGQVFKGKVAKVLPAMAEGEIQMNGTLQSSNQL
FQSGRVIVLIDIEDDAIRRQFPAGVAGQVAVYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH

Sequences:

>Translated_381_residues
MDLLLILTYASICIVIFKVFKIPMNKWTVPTAVLGGVVLIGALLLIMNYNHPYSRFAREYYVTIPITPAVKGLVISVEAK
PNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQLAAAWEAAKANVARVAADRERNKSAYDRYEQGHRKGGANSP
FTALELDNRRQLFFASEAQLTAAQAEELRARLAYESNVDGVNSKVAGLQGDLESALYNLEQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLQEGDEAEVVLDAAPGQVFKGKVAKVLPAMAEGEIQMNGTLQSSNQL
FQSGRVIVLIDIEDDAIRRQFPAGVAGQVAVYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH
>Mature_381_residues
MDLLLILTYASICIVIFKVFKIPMNKWTVPTAVLGGVVLIGALLLIMNYNHPYSRFAREYYVTIPITPAVKGLVISVEAK
PNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQLAAAWEAAKANVARVAADRERNKSAYDRYEQGHRKGGANSP
FTALELDNRRQLFFASEAQLTAAQAEELRARLAYESNVDGVNSKVAGLQGDLESALYNLEQTVVRAPADGIVTQMALRPG
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLQEGDEAEVVLDAAPGQVFKGKVAKVLPAMAEGEIQMNGTLQSSNQL
FQSGRVIVLIDIEDDAIRRQFPAGVAGQVAVYTEHFHHVAVMRKVLLRMQGWLNYLFFDGH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=379, Percent_Identity=46.9656992084433, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790024, Length=379, Percent_Identity=45.1187335092348, Blast_Score=347, Evalue=6e-97,
Organism=Escherichia coli, GI1790519, Length=243, Percent_Identity=28.3950617283951, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42094; Mature: 42094

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLILTYASICIVIFKVFKIPMNKWTVPTAVLGGVVLIGALLLIMNYNHPYSRFAREY
CCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEE
YVTIPITPAVKGLVISVEAKPNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQL
EEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AAAWEAAKANVARVAADRERNKSAYDRYEQGHRKGGANSPFTALELDNRRQLFFASEAQL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHH
TAAQAEELRARLAYESNVDGVNSKVAGLQGDLESALYNLEQTVVRAPADGIVTQMALRPG
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLQEGDEAEVVLDAAPGQVFKGKVAKVL
CEECCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCHHHCHHHHHH
PAMAEGEIQMNGTLQSSNQLFQSGRVIVLIDIEDDAIRRQFPAGVAGQVAVYTEHFHHVA
HHHHCCCEEECCEECHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCEEEHHHHHHHHHH
VMRKVLLRMQGWLNYLFFDGH
HHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure
MDLLLILTYASICIVIFKVFKIPMNKWTVPTAVLGGVVLIGALLLIMNYNHPYSRFAREY
CCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEE
YVTIPITPAVKGLVISVEAKPNTPMKQGDVLFRIDPTPFEAVVKRKKAALLAAEQEVPQL
EEEEECCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AAAWEAAKANVARVAADRERNKSAYDRYEQGHRKGGANSPFTALELDNRRQLFFASEAQL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCHH
TAAQAEELRARLAYESNVDGVNSKVAGLQGDLESALYNLEQTVVRAPADGIVTQMALRPG
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
AMAVPLPLRPVMSFIPDEQRYFAGAFWQNSLLRLQEGDEAEVVLDAAPGQVFKGKVAKVL
CEECCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCHHHCHHHHHH
PAMAEGEIQMNGTLQSSNQLFQSGRVIVLIDIEDDAIRRQFPAGVAGQVAVYTEHFHHVA
HHHHCCCEEECCEECHHHHHHHCCCEEEEEECCCHHHHHHCCCCCCCEEEHHHHHHHHHH
VMRKVLLRMQGWLNYLFFDGH
HHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]