Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 117921607

GI number: 117921607

Start: 3807197

End: 3809770

Strand: Reverse

Name: clpB [H]

Synonym: Shewana3_3169

Alternate gene names: 117921607

Gene position: 3809770-3807197 (Counterclockwise)

Preceding gene: 117921608

Following gene: 117921605

Centisome position: 76.62

GC content: 51.09

Gene sequence:

>2574_bases
ATGCGACTCGATCGTATGACCAATAAATTTCAGCTTGCCATCTCAGATGCCCAGTCGCTCGCGCTCGGGCGTGATCATCA
GTTTATCGAACCGTTACATTTGATGATGGCGTTGCTCAACCAGGATTCTGGTTCTATCCATCCTTTATTAACCCAAGCTG
GCATTCGGGTGAGTGCGCTGCGCTCGCTGTTGAGCCAAGAGCTTGAACGTCTACCGCAGGTCGAAGGCACTGGCGGCGAT
GTACAATTATCCCAAGGTTTAATTCGCTTATTAAACTTGTGCGACAAGTTGGCGCAAAAGCGCAAAGACAAATATATCTC
CAGTGAGTTGTTTGTCTTAGCGGCACTCGAGGGCAGTGATGCCTTGGCGCAATGCTTAAAGAAATCCGGCGCCACCAAAG
AGCTGCTCGAGCAAACCATTGAGCAAGTGCGCGGCGGTCAGAATGTGGATGATCCTAACGCGGAAGATCAACGCCAAGCG
CTGAAAAAGTTTACCGTTGATCTCACTGAGCGTGCCGAGCAAGGCAAACTCGACCCTGTGATTGGTCGCGACGATGAAAT
CCGCCGCACCATTCAAGTGTTGCAACGCCGTAGTAAAAACAACCCAGTGCTGATTGGTGAGCCTGGCGTGGGTAAAACCG
CGATTGTTGAAGGCCTCGCGCAGCGAATTGTGAACGGTGAAGTGCCTGAAGGGATTAAAAATAAACGCGTTTTATCCTTA
GATATGGGCGCACTGATTGCGGGCGCTAAATATCGTGGCGAGTTTGAAGAGCGTTTAAAAGCCGTGCTTAACGAGCTGGC
GCAGGAAGAAGGCCAAGTGATCCTCTTTATCGACGAGCTGCACACTATGGTGGGCGCGGGTAAAGGCGATGGCGCCATGG
ATGCGGGCAATATGCTAAAGCCTGCGCTGGCCCGTGGCGATCTTCACTGTGTGGGTGCGACCACTCTCGACGAATATCGT
CAATATATTGAAAAGGATGCCGCCCTTGAGCGCCGCTTCCAAAAAGTATTAGTGGATGAGCCTAGCGTTGAAGATACCAT
AGCGATTTTGCGTGGTCTCAAAGAGCGTTACGAGTTACATCACCATGTGGAAATTACCGATCCGGCGATTGTGGCGGCGG
CCACCATGTCGCACCGTTATGTGTCGGACCGTAAATTACCCGATAAAGCCATCGACTTGATTGACGAGGCGGCATCGAGC
ATCCGTATGCAGATGGATTCTAAGCCTGAATCCCTCGACAGATTGGAGCGCCGTGCTATCCAGTTGAAACTGGAAGAGCA
GGCATTAGCCAAAGAAAACGATGAGGCGAGCCGCCGTCGACTTGAACATTTACGTGTCGAGTTGCATGAGGTTGAGGCTA
AGGCGTCGGAGCTTAATGAAATCTGGCGCACCGAAAAAGCGGCGCTTGCAGGGACTCAGCATATTAAAGCCGACCTTGAG
CAGGCGCGGATGGATTTAGAGGTGGCGCGCCGCGCGGGCGACTTGACCCGTATGTCCGAGCTGCAATATGGCCGTATTCC
CGAGCTTGAAAAGCAACTGGACTTAGCTTCGCAAGCCGAAATGCAGGATATGACGCTGCTACGAAATAAAGTTACTGACT
TAGAAATTGCCGAAGTGCTCTCAAAGGCGACGGGGATTCCGGTTTCTAAGATGCTTGAAGGCGAGCGTGAAAAACTGCTG
CAAATGGAAGTGGCACTGCATGAGCGGGTGATTGGCCAAAACGAAGCCGTGGATGCGGTGGCCAATGCGATTCGCCGTAG
CCGCGCAGGGCTGGCCGATCCGAATCGTCCTATTGGTTCGTTCCTGTTCTTAGGACCAACCGGTGTGGGTAAAACTGAGT
TATGTAAGTCGTTGGCTAAGTTCCTCTTCGATACGGAATCGGCCTTAGTGCGCATCGACATGTCTGAATTTATGGAGAAA
CATGCGGTTTCCCGTTTAGTGGGGGCGCCTCCTGGCTATGTCGGTTATGAAGAGGGCGGTTACTTAACTGAAGCGGTGCG
TCGTAAGCCTTATTCGGTGATATTGCTCGATGAGGTGGAAAAGGCTCACCCAGACGTGTTCAACATTTTGCTGCAGGTGC
TGGATGATGGCCGCTTAACCGATGGTCAAGGTCGTACCGTCGACTTTAGAAATACGGTGATCATCATGACCTCAAACTTA
GGCTCTGACATTATCCAAGAAGGATTCGGTCACCTAAGTTATAGCGAAATGAAGAGCGCGGTGATGAATGTGGTTACCCA
TAGCTTTAGACCCGAGTTTCTAAACCGGATCGACGAGTCAGTGGTATTCCATCCCTTGGATGCGGAAAATATCAAGCATA
TTGCATCTATCCAAATTGCTTCATTGCGTAAGCGTTTGGCAGAGAAAGACTATACGCTGGAGATCACCGACGAGGCATTA
TCGTTAATCGCCGAAATTGGTTTCGACCCAGTCTATGGCGCAAGACCGCTGAAACGTGCCTTACAGCAAGAGATGGAAAA
CCCATTAGCGCAAAAATTACTGCGTGGCGATTTACTGCCCGGCAAACCGATTAAGGTCAGTTGCGCCGGCGGTGAGTTGG
TATTCGAGCAATAA

Upstream 100 bases:

>100_bases
TTGTATTAATTTCCCGCCGTCTTGCTTGAAATCGGTTAAATAGCCCCCATCTTTTAACTAACAAAATGTTATACCTCATT
TGTGAGTTTTAGGAGGCTGT

Downstream 100 bases:

>100_bases
TTTGCGCGGATGCTTACCCTGCTAAATGGTGCTTAACCTAAATAAAAAACCGAAGTCTTAGACTTCGGTTTTTTTATATC
TATATGCTACTGATAAAGTG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 857; Mature: 857

Protein sequence:

>857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGSDALAQCLKKSGATKELLEQTIEQVRGGQNVDDPNAEDQRQA
LKKFTVDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGDGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLEHLRVELHEVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTDLEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLAKFLFDTESALVRIDMSEFMEK
HAVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGHLSYSEMKSAVMNVVTHSFRPEFLNRIDESVVFHPLDAENIKHIASIQIASLRKRLAEKDYTLEITDEAL
SLIAEIGFDPVYGARPLKRALQQEMENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ

Sequences:

>Translated_857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGSDALAQCLKKSGATKELLEQTIEQVRGGQNVDDPNAEDQRQA
LKKFTVDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGDGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLEHLRVELHEVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTDLEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLAKFLFDTESALVRIDMSEFMEK
HAVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGHLSYSEMKSAVMNVVTHSFRPEFLNRIDESVVFHPLDAENIKHIASIQIASLRKRLAEKDYTLEITDEAL
SLIAEIGFDPVYGARPLKRALQQEMENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ
>Mature_857_residues
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSALRSLLSQELERLPQVEGTGGD
VQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGSDALAQCLKKSGATKELLEQTIEQVRGGQNVDDPNAEDQRQA
LKKFTVDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGDGAMDAGNMLKPALARGDLHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELHHHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASS
IRMQMDSKPESLDRLERRAIQLKLEEQALAKENDEASRRRLEHLRVELHEVEAKASELNEIWRTEKAALAGTQHIKADLE
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTDLEIAEVLSKATGIPVSKMLEGEREKLL
QMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKSLAKFLFDTESALVRIDMSEFMEK
HAVSRLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
GSDIIQEGFGHLSYSEMKSAVMNVVTHSFRPEFLNRIDESVVFHPLDAENIKHIASIQIASLRKRLAEKDYTLEITDEAL
SLIAEIGFDPVYGARPLKRALQQEMENPLAQKLLRGDLLPGKPIKVSCAGGELVFEQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=309, Percent_Identity=37.8640776699029, Blast_Score=211, Evalue=2e-54,
Organism=Escherichia coli, GI1788943, Length=848, Percent_Identity=77.9481132075472, Blast_Score=1363, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=419, Percent_Identity=39.3794749403341, Blast_Score=276, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=739, Percent_Identity=52.0974289580514, Blast_Score=769, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=852, Percent_Identity=41.6666666666667, Blast_Score=657, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95368; Mature: 95368

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSAL
CCCCHHCCHHEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHH
RSLLSQELERLPQVEGTGGDVQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGSD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
ALAQCLKKSGATKELLEQTIEQVRGGQNVDDPNAEDQRQALKKFTVDLTERAEQGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGALIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGDGAMDAGNMLK
EHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGDLHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASSIRMQMDSKPESLDRLERRAI
HCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKLEEQALAKENDEASRRRLEHLRVELHEVEAKASELNEIWRTEKAALAGTQHIKADLE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTDLEIAEVL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SKATGIPVSKMLEGEREKLLQMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELCKSLAKFLFDTESALVRIDMSEFMEKHAVSRLVGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
YLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GSDIIQEGFGHLSYSEMKSAVMNVVTHSFRPEFLNRIDESVVFHPLDAENIKHIASIQIA
CHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
SLRKRLAEKDYTLEITDEALSLIAEIGFDPVYGARPLKRALQQEMENPLAQKLLRGDLLP
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCC
GKPIKVSCAGGELVFEQ
CCCEEEEECCCCEEECC
>Mature Secondary Structure
MRLDRMTNKFQLAISDAQSLALGRDHQFIEPLHLMMALLNQDSGSIHPLLTQAGIRVSAL
CCCCHHCCHHEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHH
RSLLSQELERLPQVEGTGGDVQLSQGLIRLLNLCDKLAQKRKDKYISSELFVLAALEGSD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCH
ALAQCLKKSGATKELLEQTIEQVRGGQNVDDPNAEDQRQALKKFTVDLTERAEQGKLDPV
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRTIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGALIAGAKYRGEFEERLKAVLNELAQEEGQVILFIDELHTMVGAGKGDGAMDAGNMLK
EHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGDLHCVGATTLDEYRQYIEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HHVEITDPAIVAAATMSHRYVSDRKLPDKAIDLIDEAASSIRMQMDSKPESLDRLERRAI
HCEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKLEEQALAKENDEASRRRLEHLRVELHEVEAKASELNEIWRTEKAALAGTQHIKADLE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARMDLEVARRAGDLTRMSELQYGRIPELEKQLDLASQAEMQDMTLLRNKVTDLEIAEVL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SKATGIPVSKMLEGEREKLLQMEVALHERVIGQNEAVDAVANAIRRSRAGLADPNRPIGS
HHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FLFLGPTGVGKTELCKSLAKFLFDTESALVRIDMSEFMEKHAVSRLVGAPPGYVGYEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
YLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIIMTSNL
HHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCC
GSDIIQEGFGHLSYSEMKSAVMNVVTHSFRPEFLNRIDESVVFHPLDAENIKHIASIQIA
CHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
SLRKRLAEKDYTLEITDEALSLIAEIGFDPVYGARPLKRALQQEMENPLAQKLLRGDLLP
HHHHHHHCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCC
GKPIKVSCAGGELVFEQ
CCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]