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The map label for this gene is glmS [H]

Identifier: 117921551

GI number: 117921551

Start: 3733732

End: 3734730

Strand: Reverse

Name: glmS [H]

Synonym: Shewana3_3113

Alternate gene names: 117921551

Gene position: 3734730-3733732 (Counterclockwise)

Preceding gene: 117921552

Following gene: 117921550

Centisome position: 75.11

GC content: 49.75

Gene sequence:

>999_bases
ATGACAAACACTATTATGGAGCAAGAAGCTCGCACCGCGCCGCAGAAGATTGCGGGTCAGTTAGCCGCTAACGCCGATTT
AATGCAGCAGTTAGGTGAAAAACTGCGTGCTTTCGATCCCCGTTTTGTGATGATTGTGGGCCGTGGTTCATCGGACCATG
CGGGTGTATTTGCTAAATATCTTTTTGAAATCGAAGCGGGTGTACCCACTTTTGCTGCCGCGCCATCTGTGGCCAGCGTT
TACGGTAAAACCTTGAAGTTAGAAGGCGGATTAGTGATTGTGATTTCGCAGTCTGGCCGCAGCCCTGATATTTTAGCCCA
GGCGCGTATGGCGAAAAACGCCGGCGCGTTTTGTGTGGCGTTAGTAAACGATGAAACCGCGCCAATCAAGGATATCGTCG
ATGTCGTCGTGCCACTACGTGCAGGCGAAGAGAAAGCCGTTGCCGCAACTAAGAGCTACCTTGCAACTTTGTCGGCGATT
CTACAATTAGCCTCGGCGTGGACGCAGAGCGAATCCCTCGCCGCCGCAGTTAACTCTTTACCTCAAGCACTGCAAACTGC
GGTTGATGCTGAGCCGCAATTGACTCCAGCATCGGTTGAAAACGTGAAAAACTTAGTCGTGTTAGGCCGTGGTTTAGGCT
ATGCCGTGTCTAAGGAAATCGCACTTAAGTTAAAAGAAGTGTGTTCTATCCACGCAGAAGCCTTTAGTAGTGCTGAATTC
CTCCATGGTCCTGTTACTTTAGTGGAGAAAAAACTTACGATTGTGGATGTCTGCATCGGCGATGAGTCCTACGCTAGCCA
TATCGAACAGATTGAAAATGTGAGCCAACGTGGCGCAGATTTAGTGCATTTAAATCAAACGTCGACGGATATTCACCCAC
GTGTTGCGCCGTTAGCCTTGTTACAACGTTTTTATATCGACGTGGCCGCAGTCGCGATTGCCCGTGGTATTGACCCAGAC
CAACCCGCAGGGCTGAAAAAAGTCACTCAAACGCTGTAA

Upstream 100 bases:

>100_bases
TTCGCTCAGCAGCAATTTAACTCAGTCAACATTAATGAATAAGCCGTTTTAGCGCATCAGTGCTAAAGCAATACCCGTAT
TGATTTATAAGGTAAATAAC

Downstream 100 bases:

>100_bases
TGGATGGCCGTTGTCGCCGCGTTAATTTGAAAAGAGGTTTGGGATGAAATTCACCTTAATTGCCGAGCAACTGTTTGATG
GTGAAGCCTTCCATCGGGAT

Product: sugar isomerase (SIS)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTNTIMEQEARTAPQKIAGQLAANADLMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASV
YGKTLKLEGGLVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAI
LQLASAWTQSESLAAAVNSLPQALQTAVDAEPQLTPASVENVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPD
QPAGLKKVTQTL

Sequences:

>Translated_332_residues
MTNTIMEQEARTAPQKIAGQLAANADLMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASV
YGKTLKLEGGLVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAI
LQLASAWTQSESLAAAVNSLPQALQTAVDAEPQLTPASVENVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPD
QPAGLKKVTQTL
>Mature_331_residues
TNTIMEQEARTAPQKIAGQLAANADLMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKYLFEIEAGVPTFAAAPSVASVY
GKTLKLEGGLVIVISQSGRSPDILAQARMAKNAGAFCVALVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAIL
QLASAWTQSESLAAAVNSLPQALQTAVDAEPQLTPASVENVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEFL
HGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLALLQRFYIDVAAVAIARGIDPDQ
PAGLKKVTQTL

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=360, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI205277386, Length=317, Percent_Identity=26.4984227129338, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1790167, Length=310, Percent_Identity=29.0322580645161, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17539970, Length=296, Percent_Identity=26.0135135135135, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=253, Percent_Identity=26.4822134387352, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17532897, Length=253, Percent_Identity=26.4822134387352, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322745, Length=370, Percent_Identity=23.5135135135135, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357745, Length=318, Percent_Identity=25.4716981132075, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35160; Mature: 35029

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTIMEQEARTAPQKIAGQLAANADLMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKY
CCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LFEIEAGVPTFAAAPSVASVYGKTLKLEGGLVIVISQSGRSPDILAQARMAKNAGAFCVA
HHHHHCCCCCHHCCCCHHHHHCCEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEE
LVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAILQLASAWTQSESLAAAVNSL
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PQALQTAVDAEPQLTPASVENVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAIARGIDPDQPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
TNTIMEQEARTAPQKIAGQLAANADLMQQLGEKLRAFDPRFVMIVGRGSSDHAGVFAKY
CCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
LFEIEAGVPTFAAAPSVASVYGKTLKLEGGLVIVISQSGRSPDILAQARMAKNAGAFCVA
HHHHHCCCCCHHCCCCHHHHHCCEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEE
LVNDETAPIKDIVDVVVPLRAGEEKAVAATKSYLATLSAILQLASAWTQSESLAAAVNSL
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
PQALQTAVDAEPQLTPASVENVKNLVVLGRGLGYAVSKEIALKLKEVCSIHAEAFSSAEF
HHHHHHHHCCCCCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHH
LHGPVTLVEKKLTIVDVCIGDESYASHIEQIENVSQRGADLVHLNQTSTDIHPRVAPLAL
HCCCHHHHHCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHH
LQRFYIDVAAVAIARGIDPDQPAGLKKVTQTL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]