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The map label for this gene is nagA [H]

Identifier: 117921550

GI number: 117921550

Start: 3732552

End: 3733688

Strand: Reverse

Name: nagA [H]

Synonym: Shewana3_3112

Alternate gene names: 117921550

Gene position: 3733688-3732552 (Counterclockwise)

Preceding gene: 117921551

Following gene: 117921549

Centisome position: 75.09

GC content: 53.65

Gene sequence:

>1137_bases
ATGAAATTCACCTTAATTGCCGAGCAACTGTTTGATGGTGAAGCCTTCCATCGGGATGTGCCTGTCACCATTGAAGATGG
TCTGATAGCCAGCTTAGACACCGCATCGGGTGCTAAGGAAATTCGCTACCCAGGCACCCTAGTGCCAGGTTTTATCGATG
TACAAGTTAACGGCGGTGGCGGCGCGTTATTCAATAGCAGCCCAACGGTCGCTTGCATTGAAACCATAGGCAAGGCGCAT
GCTCGCTTTGGTACCACTGGCTTTTTACCTACGCTTATCACAGATGATGTGCAGGTGATGGCCAAGGCTGCCGATGCGGT
TGCCAGTGCGGTCGCGCAAAAGAGCGCTGGCGTATTAGGCGTACATTTTGAAGGTCCGCATCTTTCGGTACCTAAAAAAG
GCGTGCATCCACAAGGTTTTATCCGTGAGATCACCGAGGCTGAACTGGCGATTTTTTGCCGTCAGGATTTAGGGATTCGA
GTGGTGACCTTAGCACCTGAAAATGTCTCGCCTGAGGTGATCCGCCTGTTGGTGGAGTCGGGCGTTAAAGTGTGTTTAGG
CCACTCCAATGCGGACTACGATACCGTTGTCGCAGCCTTAGCGGCGGGGGCGACAGGCTTTACTCACCTCTACAATGCTA
TGTCACCCTTAGGTTCCCGAGAGCCTGGCGTGGTAGGCGCGGCGATTGAGAGCGAAACCGCTTGGTGTGGTTTGATTGTC
GATGGCCACCATGTGCATCCAGCGGCCGCAAGAGTTGCCCTGCGCGCTAAACCCCGTGGCAAAGTGATGTTGGTAACTGA
TGCCATGCCACCAGTAGGCATGGATGATGAAACCAGCTTTGAGCTGTTTGGTACTCAGGTACTGCGTGTCGGCGATAGAT
TAAATGCGGTGACGGGTGAACTGGCGGGCTGTGTGTTAGACATGGCGACCGCAGTTGAGAACAGTGTGAAGATGCTCGGT
TTACCGCTTGGTGAGGCCCTGCGGATGGCGTCTTTGTATCCAGCCGAGTTCCTTGGCATTGCCGAGAGCGTCGGTCGGTT
AGCCGTAGGGCAGCGTGCCGATCTAGTGCTGCTAGATAATCAGTACAAAGTGCTGGCCAACTATATTGCTGGAAATGCGG
TTTATGTTCGCCCTTAG

Upstream 100 bases:

>100_bases
CGTGGTATTGACCCAGACCAACCCGCAGGGCTGAAAAAAGTCACTCAAACGCTGTAATGGATGGCCGTTGTCGCCGCGTT
AATTTGAAAAGAGGTTTGGG

Downstream 100 bases:

>100_bases
TGTGGGTTGAGTCAGTAAAGCGTTAACCTTGGCCCTTGTCGTATTTTGATGACAGGGGCTAAGTTTTTTTATTGTACAGT
CTGCATTTTGCTCAAAAGTT

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKFTLIAEQLFDGEAFHRDVPVTIEDGLIASLDTASGAKEIRYPGTLVPGFIDVQVNGGGGALFNSSPTVACIETIGKAH
ARFGTTGFLPTLITDDVQVMAKAADAVASAVAQKSAGVLGVHFEGPHLSVPKKGVHPQGFIREITEAELAIFCRQDLGIR
VVTLAPENVSPEVIRLLVESGVKVCLGHSNADYDTVVAALAAGATGFTHLYNAMSPLGSREPGVVGAAIESETAWCGLIV
DGHHVHPAAARVALRAKPRGKVMLVTDAMPPVGMDDETSFELFGTQVLRVGDRLNAVTGELAGCVLDMATAVENSVKMLG
LPLGEALRMASLYPAEFLGIAESVGRLAVGQRADLVLLDNQYKVLANYIAGNAVYVRP

Sequences:

>Translated_378_residues
MKFTLIAEQLFDGEAFHRDVPVTIEDGLIASLDTASGAKEIRYPGTLVPGFIDVQVNGGGGALFNSSPTVACIETIGKAH
ARFGTTGFLPTLITDDVQVMAKAADAVASAVAQKSAGVLGVHFEGPHLSVPKKGVHPQGFIREITEAELAIFCRQDLGIR
VVTLAPENVSPEVIRLLVESGVKVCLGHSNADYDTVVAALAAGATGFTHLYNAMSPLGSREPGVVGAAIESETAWCGLIV
DGHHVHPAAARVALRAKPRGKVMLVTDAMPPVGMDDETSFELFGTQVLRVGDRLNAVTGELAGCVLDMATAVENSVKMLG
LPLGEALRMASLYPAEFLGIAESVGRLAVGQRADLVLLDNQYKVLANYIAGNAVYVRP
>Mature_378_residues
MKFTLIAEQLFDGEAFHRDVPVTIEDGLIASLDTASGAKEIRYPGTLVPGFIDVQVNGGGGALFNSSPTVACIETIGKAH
ARFGTTGFLPTLITDDVQVMAKAADAVASAVAQKSAGVLGVHFEGPHLSVPKKGVHPQGFIREITEAELAIFCRQDLGIR
VVTLAPENVSPEVIRLLVESGVKVCLGHSNADYDTVVAALAAGATGFTHLYNAMSPLGSREPGVVGAAIESETAWCGLIV
DGHHVHPAAARVALRAKPRGKVMLVTDAMPPVGMDDETSFELFGTQVLRVGDRLNAVTGELAGCVLDMATAVENSVKMLG
LPLGEALRMASLYPAEFLGIAESVGRLAVGQRADLVLLDNQYKVLANYIAGNAVYVRP

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=373, Percent_Identity=35.9249329758713, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI224922791, Length=374, Percent_Identity=36.3636363636364, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786892, Length=383, Percent_Identity=38.3812010443864, Blast_Score=224, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=33.5243553008596, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19920392, Length=343, Percent_Identity=37.9008746355685, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281361140, Length=355, Percent_Identity=36.6197183098592, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39633; Mature: 39633

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTLIAEQLFDGEAFHRDVPVTIEDGLIASLDTASGAKEIRYPGTLVPGFIDVQVNGGG
CEEEEEHHHHHCCCHHCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GALFNSSPTVACIETIGKAHARFGTTGFLPTLITDDVQVMAKAADAVASAVAQKSAGVLG
CEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VHFEGPHLSVPKKGVHPQGFIREITEAELAIFCRQDLGIRVVTLAPENVSPEVIRLLVES
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVVAALAAGATGFTHLYNAMSPLGSREPGVVGAAIESETAWCGLIV
CCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEE
DGHHVHPAAARVALRAKPRGKVMLVTDAMPPVGMDDETSFELFGTQVLRVGDRLNAVTGE
ECCCCCHHHHHEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAGCVLDMATAVENSVKMLGLPLGEALRMASLYPAEFLGIAESVGRLAVGQRADLVLLDN
HHHHHHHHHHHHHHCHHEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECC
QYKVLANYIAGNAVYVRP
CHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MKFTLIAEQLFDGEAFHRDVPVTIEDGLIASLDTASGAKEIRYPGTLVPGFIDVQVNGGG
CEEEEEHHHHHCCCHHCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GALFNSSPTVACIETIGKAHARFGTTGFLPTLITDDVQVMAKAADAVASAVAQKSAGVLG
CEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VHFEGPHLSVPKKGVHPQGFIREITEAELAIFCRQDLGIRVVTLAPENVSPEVIRLLVES
EEECCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVVAALAAGATGFTHLYNAMSPLGSREPGVVGAAIESETAWCGLIV
CCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEE
DGHHVHPAAARVALRAKPRGKVMLVTDAMPPVGMDDETSFELFGTQVLRVGDRLNAVTGE
ECCCCCHHHHHEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
LAGCVLDMATAVENSVKMLGLPLGEALRMASLYPAEFLGIAESVGRLAVGQRADLVLLDN
HHHHHHHHHHHHHHCHHEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECC
QYKVLANYIAGNAVYVRP
CHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]