Click here to switch to the map view.

The map label for this gene is hcr [H]

Identifier: 117921449

GI number: 117921449

Start: 3616021

End: 3617163

Strand: Reverse

Name: hcr [H]

Synonym: Shewana3_3010

Alternate gene names: 117921449

Gene position: 3617163-3616021 (Counterclockwise)

Preceding gene: 117921450

Following gene: 117921448

Centisome position: 72.75

GC content: 48.21

Gene sequence:

>1143_bases
ATGGATACAAAGACGATGAATATCAGTACTATGCAAAATATCATGCCAAGTCCCGCTTTATCTTCTGCGCCTGCAAGTGT
TGTGGGTTTTAGCCAGTTAGTGTGTGTGGAGCGCTGGAACGAAACCGCCGATGTGGTGAGTTTTCGTTTTCAAGCCGGTG
AGCCGATGAAGTTTGATTATAAGCCGGGGCAATTTATGACCTTAGTGCTAGAGATCAATGGTGAGCAGGCTTGCCGCAGT
TACACCTTGTCCTCAACCCCTTCGAGACCTTATTCCTTAATGTTAACCATTAAGCGAGTCGATGGCGGACTGGTGTCGAA
TTACTTGATTGATCATTTACAGCCGGGGCAAACGGTACGCGTCTTACCGCCAACCGGGCAGTTTAATCTGTTTGATATTC
CTGCCAAAAAATACCTATTTTTGAGTGCAGGCTGTGGGATCACGCCCATGTATTCGATGTCGCGTTATTTAACCGACAGC
CAAATGAATGCTGACATTGCCTTTGTGCACAGCGCTCGTACCCAGGCCGATATTATTTTTAAAACCTCATTAGAGACCAT
GGCTACGCGCCATCGAGATTTTAAGCTGCGTTATATTGTTGAGGATGTCACCGCTGACACGGCTTGGCATCCCGAGGCGG
TATTGCATAATGTCGGCCGTTTAAGACCTGATAATCTACGAGATTTAGTCCCCGACTTTGCCGAGCGAACCGTGTTTTTG
TGCGGACCAGAGCCTTATATGCAGGCGGTCAAAACGATTCTAGCTGAGCTTAACTTCGATATGACTCAGTTGTATCACGA
GAGTTTTGCTACTGCGGTGAAAGAGGCGCAATCCCGCGTAAAACAGGCCGAAATGCAGACTGAAGCTCCTGAGAGTGGTA
GCAACAGTTTTATGTTATCTATTGGCGATAAAAAGCGGGCTTTAACGGCCGAGCAAACCTTGCTTGAGGGGATTGAAGCC
GAAGGTTTGCCGATAATTGCGGCCTGTCGCTCGGGCGTATGCGGTGCGTGCAAATGCCAAGTGCTCGAAGGGGAGACCGA
GTCCACAAGTAGCATGACCTTAACACCTAGCGAAATCGAAGCCGGATATGTGTTAGCTTGCTCGACTAAACTCAAATCGG
ATGTAACGCTGTCTTTGACCTGA

Upstream 100 bases:

>100_bases
CACCACCACAGTTGAAGCCGATCTGAAGACCATGCTGAACGTGGCCTAGGCCGATTTATGCATGGAGTCACTGCGGCTTT
CGCGTTAAAGCCGCAGTGTT

Downstream 100 bases:

>100_bases
CATTAGCCTTTGAAGGGCATAGGTTGATTCAAAAAATCGGTGGTTTAAAAGATCTTGCGCAGAAATATTTTTGCGCCTTA
GTTGCGATTATGTCTGCGAG

Product: oxidoreductase FAD-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDTKTMNISTMQNIMPSPALSSAPASVVGFSQLVCVERWNETADVVSFRFQAGEPMKFDYKPGQFMTLVLEINGEQACRS
YTLSSTPSRPYSLMLTIKRVDGGLVSNYLIDHLQPGQTVRVLPPTGQFNLFDIPAKKYLFLSAGCGITPMYSMSRYLTDS
QMNADIAFVHSARTQADIIFKTSLETMATRHRDFKLRYIVEDVTADTAWHPEAVLHNVGRLRPDNLRDLVPDFAERTVFL
CGPEPYMQAVKTILAELNFDMTQLYHESFATAVKEAQSRVKQAEMQTEAPESGSNSFMLSIGDKKRALTAEQTLLEGIEA
EGLPIIAACRSGVCGACKCQVLEGETESTSSMTLTPSEIEAGYVLACSTKLKSDVTLSLT

Sequences:

>Translated_380_residues
MDTKTMNISTMQNIMPSPALSSAPASVVGFSQLVCVERWNETADVVSFRFQAGEPMKFDYKPGQFMTLVLEINGEQACRS
YTLSSTPSRPYSLMLTIKRVDGGLVSNYLIDHLQPGQTVRVLPPTGQFNLFDIPAKKYLFLSAGCGITPMYSMSRYLTDS
QMNADIAFVHSARTQADIIFKTSLETMATRHRDFKLRYIVEDVTADTAWHPEAVLHNVGRLRPDNLRDLVPDFAERTVFL
CGPEPYMQAVKTILAELNFDMTQLYHESFATAVKEAQSRVKQAEMQTEAPESGSNSFMLSIGDKKRALTAEQTLLEGIEA
EGLPIIAACRSGVCGACKCQVLEGETESTSSMTLTPSEIEAGYVLACSTKLKSDVTLSLT
>Mature_380_residues
MDTKTMNISTMQNIMPSPALSSAPASVVGFSQLVCVERWNETADVVSFRFQAGEPMKFDYKPGQFMTLVLEINGEQACRS
YTLSSTPSRPYSLMLTIKRVDGGLVSNYLIDHLQPGQTVRVLPPTGQFNLFDIPAKKYLFLSAGCGITPMYSMSRYLTDS
QMNADIAFVHSARTQADIIFKTSLETMATRHRDFKLRYIVEDVTADTAWHPEAVLHNVGRLRPDNLRDLVPDFAERTVFL
CGPEPYMQAVKTILAELNFDMTQLYHESFATAVKEAQSRVKQAEMQTEAPESGSNSFMLSIGDKKRALTAEQTLLEGIEA
EGLPIIAACRSGVCGACKCQVLEGETESTSSMTLTPSEIEAGYVLACSTKLKSDVTLSLT

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=219, Percent_Identity=27.3972602739726, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787098, Length=340, Percent_Identity=34.4117647058824, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1787658, Length=362, Percent_Identity=27.0718232044199, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1788903, Length=221, Percent_Identity=27.1493212669683, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788104, Length=329, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323552, Length=199, Percent_Identity=26.1306532663317, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=200, Percent_Identity=24.5, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322699, Length=179, Percent_Identity=26.2569832402235, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41928; Mature: 41928

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTKTMNISTMQNIMPSPALSSAPASVVGFSQLVCVERWNETADVVSFRFQAGEPMKFDY
CCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEECCCCCEEECC
KPGQFMTLVLEINGEQACRSYTLSSTPSRPYSLMLTIKRVDGGLVSNYLIDHLQPGQTVR
CCCCEEEEEEEECCCHHHHEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEE
VLPPTGQFNLFDIPAKKYLFLSAGCGITPMYSMSRYLTDSQMNADIAFVHSARTQADIIF
EECCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
KTSLETMATRHRDFKLRYIVEDVTADTAWHPEAVLHNVGRLRPDNLRDLVPDFAERTVFL
ECCHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCEEEE
CGPEPYMQAVKTILAELNFDMTQLYHESFATAVKEAQSRVKQAEMQTEAPESGSNSFMLS
ECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IGDKKRALTAEQTLLEGIEAEGLPIIAACRSGVCGACKCQVLEGETESTSSMTLTPSEIE
ECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEECHHHCC
AGYVLACSTKLKSDVTLSLT
CCEEEEECCCCCCCEEEEEC
>Mature Secondary Structure
MDTKTMNISTMQNIMPSPALSSAPASVVGFSQLVCVERWNETADVVSFRFQAGEPMKFDY
CCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEECCCCCEEECC
KPGQFMTLVLEINGEQACRSYTLSSTPSRPYSLMLTIKRVDGGLVSNYLIDHLQPGQTVR
CCCCEEEEEEEECCCHHHHEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEE
VLPPTGQFNLFDIPAKKYLFLSAGCGITPMYSMSRYLTDSQMNADIAFVHSARTQADIIF
EECCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEE
KTSLETMATRHRDFKLRYIVEDVTADTAWHPEAVLHNVGRLRPDNLRDLVPDFAERTVFL
ECCHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCEEEE
CGPEPYMQAVKTILAELNFDMTQLYHESFATAVKEAQSRVKQAEMQTEAPESGSNSFMLS
ECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
IGDKKRALTAEQTLLEGIEAEGLPIIAACRSGVCGACKCQVLEGETESTSSMTLTPSEIE
ECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEECHHHCC
AGYVLACSTKLKSDVTLSLT
CCEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]