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The map label for this gene is yiaY [H]

Identifier: 117921378

GI number: 117921378

Start: 3528348

End: 3529496

Strand: Direct

Name: yiaY [H]

Synonym: Shewana3_2938

Alternate gene names: 117921378

Gene position: 3528348-3529496 (Clockwise)

Preceding gene: 117921376

Following gene: 117921379

Centisome position: 70.96

GC content: 49.52

Gene sequence:

>1149_bases
ATGGCTGCTAAATTTTTTATCCCTTCCGTCAACGTATTAGGCAAAGGCGCCGTCAATGACGCTATCGGAGATATCAAAAC
CTTAGGCTTTAAACGCGCGTTAATCGTGACGGATAAACCTCTAGTCAAGATTGGTCTGGTCGGTGAAGTGGCCGAAAAGC
TCGGTCAAAACGGCATTACTTCAACCGTGTTTGATGGCGTGCAACCCAACCCAACCGTCGGTAACGTCGAAGCGGGTCTT
GCACTATTAAAAGCCAATCAATGTGATTTTGTGATTTCATTAGGCGGCGGTTCACCCCACGATTGCGCTAAGGGTATCGC
CTTGGTTGCCACCAACGGCGGCAGCATCAAAGACTATGAAGGGTTAGACCAATCCGCTAAGCCACAACTGCCATTAGTAG
CCATTAACACTACTGCTGGTACCGCCAGTGAAATGACCCGTTTTTGTATCATCACTGACGAAGCTCGCCATATTAAAATG
GCAATTGTCGATAAACACACCACCCCATTATTGTCTGTGAATGACCCTGAGCTGATGCTGAAAAAACCAGCGAGCCTCAC
CGCCGCAACAGGCATGGACGCGCTGACCCACGCGGTTGAAGCCTATGTGTCTATCGCTGCTAACCCAATTACCGATGCCT
GCGCCATTAAGGCCATTGAACTTATCCAAGGCAACTTAGTGAATGCGGTAAAGCAAGGCCAAGATATTGAGGCCCGTGAG
CAAATGGCCTATGCGCAATTCTTGGCGGGTATGGCCTTCAACAACGCCAGCTTAGGTTATGTACATGCGATGGCGCACCA
ATTAGGCGGTTTCTACGACCTGCCCCACGGTGTGTGTAACGCCCTATTATTACCCCATGTGCAAGAATACAACGCCAAAG
TGGTACCAGAACGCTTAAAGGATATTGCTAAGGCGATGGGTGTCGATGTAGCCAATATGACGGATGAACAAGGTGCAGCG
GCGGCGATCGCCGCGATTAAGGCCCTATCCGTTGCGGTAAACATTCCAGAAAACCTGACATTACTCGGGGTTAAAGCGGA
AGATATTCCAACCCTGGCCGAAAACGCCTTAAAGGATGCCTGTGGTTTCACTAACCCTAAACAGGCAACCCATGAAGAGA
TCTGCCAGATCTTCGCTAACGCGTTATAA

Upstream 100 bases:

>100_bases
ACTGCCTAAGCCGATCTAGATCACATCTTACATACCCCTTAATTGGTAGCTTGGTCACCAGAAAGAAACAAATTTAATTT
ACAAGCAAATAGGTGGACTT

Downstream 100 bases:

>100_bases
GCCAAAACGCGTCATAGAGCATTCGCATTAACGCCGTCTGTCGCGCGCCAATTGACAGGATGTTGTTCGGCTAGCGCAAG
CTAACGACATGAGAATCGGC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAAKFFIPSVNVLGKGAVNDAIGDIKTLGFKRALIVTDKPLVKIGLVGEVAEKLGQNGITSTVFDGVQPNPTVGNVEAGL
ALLKANQCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIQGNLVNAVKQGQDIEARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAKVVPERLKDIAKAMGVDVANMTDEQGAA
AAIAAIKALSVAVNIPENLTLLGVKAEDIPTLAENALKDACGFTNPKQATHEEICQIFANAL

Sequences:

>Translated_382_residues
MAAKFFIPSVNVLGKGAVNDAIGDIKTLGFKRALIVTDKPLVKIGLVGEVAEKLGQNGITSTVFDGVQPNPTVGNVEAGL
ALLKANQCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIQGNLVNAVKQGQDIEARE
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAKVVPERLKDIAKAMGVDVANMTDEQGAA
AAIAAIKALSVAVNIPENLTLLGVKAEDIPTLAENALKDACGFTNPKQATHEEICQIFANAL
>Mature_381_residues
AAKFFIPSVNVLGKGAVNDAIGDIKTLGFKRALIVTDKPLVKIGLVGEVAEKLGQNGITSTVFDGVQPNPTVGNVEAGLA
LLKANQCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMA
IVDKHTTPLLSVNDPELMLKKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIQGNLVNAVKQGQDIEAREQ
MAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAKVVPERLKDIAKAMGVDVANMTDEQGAAA
AIAAIKALSVAVNIPENLTLLGVKAEDIPTLAENALKDACGFTNPKQATHEEICQIFANAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=413, Percent_Identity=27.8450363196126, Blast_Score=141, Evalue=9e-34,
Organism=Escherichia coli, GI48994951, Length=381, Percent_Identity=69.0288713910761, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=44.53125, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=37.4005305039788, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1787493, Length=407, Percent_Identity=31.9410319410319, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1789386, Length=321, Percent_Identity=25.8566978193146, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=410, Percent_Identity=26.5853658536585, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=54.8812664907652, Blast_Score=412, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=27.8048780487805, Blast_Score=152, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39957; Mature: 39825

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKFFIPSVNVLGKGAVNDAIGDIKTLGFKRALIVTDKPLVKIGLVGEVAEKLGQNGIT
CCCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEHHHHHHHHHCCCCCC
STVFDGVQPNPTVGNVEAGLALLKANQCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHHCCCCCCCCCCCHHHCEEEEECCCCCEEEEECCCCHHHHHCCEEEEEECCCCCCCCC
GLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLLSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHEE
KKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIQGNLVNAVKQGQDIEARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCHHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAKVVPERLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DIAKAMGVDVANMTDEQGAAAAIAAIKALSVAVNIPENLTLLGVKAEDIPTLAENALKDA
HHHHHHCCCHHCCCCCCCHHHHHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHHHH
CGFTNPKQATHEEICQIFANAL
HCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAKFFIPSVNVLGKGAVNDAIGDIKTLGFKRALIVTDKPLVKIGLVGEVAEKLGQNGIT
CCEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEHHHHHHHHHCCCCCC
STVFDGVQPNPTVGNVEAGLALLKANQCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHHCCCCCCCCCCCHHHCEEEEECCCCCEEEEECCCCHHHHHCCEEEEEECCCCCCCCC
GLDQSAKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLLSVNDPELML
CCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCHHEE
KKPASLTAATGMDALTHAVEAYVSIAANPITDACAIKAIELIQGNLVNAVKQGQDIEARE
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCHHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQEYNAKVVPERLK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECHHHHH
DIAKAMGVDVANMTDEQGAAAAIAAIKALSVAVNIPENLTLLGVKAEDIPTLAENALKDA
HHHHHHCCCHHCCCCCCCHHHHHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHHHH
CGFTNPKQATHEEICQIFANAL
HCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]