Click here to switch to the map view.

The map label for this gene is cynX [H]

Identifier: 117921301

GI number: 117921301

Start: 3419079

End: 3420275

Strand: Direct

Name: cynX [H]

Synonym: Shewana3_2860

Alternate gene names: 117921301

Gene position: 3419079-3420275 (Clockwise)

Preceding gene: 117921295

Following gene: 117921304

Centisome position: 68.76

GC content: 49.71

Gene sequence:

>1197_bases
ATGTCTCATATTTTATCCACTAGGGGCAATCAACTGATGATAGGCGTCAGTCTGTTACTTATCGGGCTTAATCTGCGCCC
CATTCTTGCCTCTGTTGGCCCATTACTGCCGAGTATTCAACAGGATATCTCCTTAAGTTTTGCCCTCGCCTCTATGCTCA
CCCTACTACCAGTCCTCGCCATGGGAATGGGTTGTTTCGTTGGTTTTAAGATTGCTAAAGGCTTGGGGTTTGCAAACACT
GTGACGGTATCGCTGCTATTTCTGCTGATTGCAACTGCGATGCGTTTTTGGGTCGAGACGGCGAATGCGCTGATCTGTTC
TGCACTTTTAGCTGGCATGGGTATCGCTCTCATCCAAACCTTAATGCCTACTCTGATTAAACAAAACTTTGCCGACAAAA
CGCCGTTGATGATGGGCTTATATGTCACCGCCATTATGGGCGGGGCGGCACTGGCCGCCAGCAGCGCACCATTTATAGCG
GCCGATTTAGGCTGGCGAGCAGGCTTAGGCCATTGGACTTGGTTAGCCCTCATCGCCATCTTGCTATGGATTGTCAGCCG
AAAACATCTTGCCCTGCCGAGTCATACCGACAAACAGGCGGAATACTCATTTTGGCGCTATCGCCGCAGTTGGTTATTGG
CACTGTTTTTTGCTTTAGGAACAAGTTGTTATGTCTGCGTGCTCGCCTGGTTAGCACCTTATGCCATCGAGTTAGGTTAT
AGCCAAACCCAGGCAGGATTAGCCTTAGGCTTCCTCACCAGTATGGAAGTGATCGCAGGCTTAGTTTTTCCTTGGCTTGC
CAGCAAATCGACGGATAGACGGGCGATTATTGCCTTACTGTGTCTGTTGCAACTCATTGGTTTTATGGGATTCGCCCTCG
CTCCACAGGTGTCGATATTCCTCTGGGCCGCACTGGCGGGACTCGGGATTGGTGGTATTTTCCCGCTGAGTTTGATTGTG
ACTATGGATCATCAACAGAATCCGCTGTTAGCGGGTAAGTTAACCGCCTTTGTGCAGGGTATTGGCTACAGTATTGCCGC
TATCTCACCTTGGATAGCGGGACTTATTCGCGATAATTTCCAAAGCTTTAATATGGCCTGGTTATTACTTGCGGCGCTGA
GTGTCATCGCTTATCTGCTGTCGCGGCAATTTAATCCGAGCGGCTATGCCCAGCACTATCGACAAGTGATAGCCTAG

Upstream 100 bases:

>100_bases
TATAAAGATACTTTTCATAAAGTTTAAATCAGTTTCACAGTGCAAACTGTTCAACGGATTGTGTTAGCCATTTTTATTCG
ACCCAGCATAGGAGTATGCG

Downstream 100 bases:

>100_bases
GATTTAAGCACATAAAAAACCGCCCAATTTGTAAAAATTGGGCGGTTCAGGTATCAAGCTAACAGCTTAAACGCGAGTCG
ATTAAGACTTCTTCACAAAG

Product: major facilitator transporter

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSHILSTRGNQLMIGVSLLLIGLNLRPILASVGPLLPSIQQDISLSFALASMLTLLPVLAMGMGCFVGFKIAKGLGFANT
VTVSLLFLLIATAMRFWVETANALICSALLAGMGIALIQTLMPTLIKQNFADKTPLMMGLYVTAIMGGAALAASSAPFIA
ADLGWRAGLGHWTWLALIAILLWIVSRKHLALPSHTDKQAEYSFWRYRRSWLLALFFALGTSCYVCVLAWLAPYAIELGY
SQTQAGLALGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGFALAPQVSIFLWAALAGLGIGGIFPLSLIV
TMDHQQNPLLAGKLTAFVQGIGYSIAAISPWIAGLIRDNFQSFNMAWLLLAALSVIAYLLSRQFNPSGYAQHYRQVIA

Sequences:

>Translated_398_residues
MSHILSTRGNQLMIGVSLLLIGLNLRPILASVGPLLPSIQQDISLSFALASMLTLLPVLAMGMGCFVGFKIAKGLGFANT
VTVSLLFLLIATAMRFWVETANALICSALLAGMGIALIQTLMPTLIKQNFADKTPLMMGLYVTAIMGGAALAASSAPFIA
ADLGWRAGLGHWTWLALIAILLWIVSRKHLALPSHTDKQAEYSFWRYRRSWLLALFFALGTSCYVCVLAWLAPYAIELGY
SQTQAGLALGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGFALAPQVSIFLWAALAGLGIGGIFPLSLIV
TMDHQQNPLLAGKLTAFVQGIGYSIAAISPWIAGLIRDNFQSFNMAWLLLAALSVIAYLLSRQFNPSGYAQHYRQVIA
>Mature_397_residues
SHILSTRGNQLMIGVSLLLIGLNLRPILASVGPLLPSIQQDISLSFALASMLTLLPVLAMGMGCFVGFKIAKGLGFANTV
TVSLLFLLIATAMRFWVETANALICSALLAGMGIALIQTLMPTLIKQNFADKTPLMMGLYVTAIMGGAALAASSAPFIAA
DLGWRAGLGHWTWLALIAILLWIVSRKHLALPSHTDKQAEYSFWRYRRSWLLALFFALGTSCYVCVLAWLAPYAIELGYS
QTQAGLALGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGFALAPQVSIFLWAALAGLGIGGIFPLSLIVT
MDHQQNPLLAGKLTAFVQGIGYSIAAISPWIAGLIRDNFQSFNMAWLLLAALSVIAYLLSRQFNPSGYAQHYRQVIA

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=375, Percent_Identity=37.0666666666667, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1788092, Length=371, Percent_Identity=28.0323450134771, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42941; Mature: 42810

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHILSTRGNQLMIGVSLLLIGLNLRPILASVGPLLPSIQQDISLSFALASMLTLLPVLA
CCCCHHCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMGCFVGFKIAKGLGFANTVTVSLLFLLIATAMRFWVETANALICSALLAGMGIALIQT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPTLIKQNFADKTPLMMGLYVTAIMGGAALAASSAPFIAADLGWRAGLGHWTWLALIAI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHH
LLWIVSRKHLALPSHTDKQAEYSFWRYRRSWLLALFFALGTSCYVCVLAWLAPYAIELGY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SQTQAGLALGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGFALAPQVSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWAALAGLGIGGIFPLSLIVTMDHQQNPLLAGKLTAFVQGIGYSIAAISPWIAGLIRDNF
HHHHHHHCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
QSFNMAWLLLAALSVIAYLLSRQFNPSGYAQHYRQVIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
SHILSTRGNQLMIGVSLLLIGLNLRPILASVGPLLPSIQQDISLSFALASMLTLLPVLA
CCCHHCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGMGCFVGFKIAKGLGFANTVTVSLLFLLIATAMRFWVETANALICSALLAGMGIALIQT
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMPTLIKQNFADKTPLMMGLYVTAIMGGAALAASSAPFIAADLGWRAGLGHWTWLALIAI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHH
LLWIVSRKHLALPSHTDKQAEYSFWRYRRSWLLALFFALGTSCYVCVLAWLAPYAIELGY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SQTQAGLALGFLTSMEVIAGLVFPWLASKSTDRRAIIALLCLLQLIGFMGFALAPQVSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWAALAGLGIGGIFPLSLIVTMDHQQNPLLAGKLTAFVQGIGYSIAAISPWIAGLIRDNF
HHHHHHHCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
QSFNMAWLLLAALSVIAYLLSRQFNPSGYAQHYRQVIA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]