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The map label for this gene is ycgM [H]

Identifier: 117921298

GI number: 117921298

Start: 3416612

End: 3417238

Strand: Reverse

Name: ycgM [H]

Synonym: Shewana3_2857

Alternate gene names: 117921298

Gene position: 3417238-3416612 (Counterclockwise)

Preceding gene: 117921299

Following gene: 117921297

Centisome position: 68.73

GC content: 48.17

Gene sequence:

>627_bases
ATGAAGACTGTTAACGTCGGTGATAAACAGATTTGCCCGAGTAAGATTCTGTGTATTGGGCGAAATTATGTCGACCATAT
CCACGAGCTGGGTAATGACATTCCCGAAGACATGGTGGTGTTTTTCAAGCCAAACTCGGCTATTAGCACTGTGCTGCATG
CTGAGCATTTAGGTGAGACGCTGCACTATGAAACTGAGCTGTGTTTTATCTATCAGCAGGGACGTTTTAGCCATGTTGGG
GTTGGGCTGGATCTCACGAAGCGAGAGCTGCAAAGTAAACTGAAAACCAAGGGATTACCCTGGGAAAAGGCCAAGGCCTT
CGATGGCGCGGCGCTATTTAGTCCCTTTGTCGCTATTGATGATGCCAGCGCGGCATTTGAATTCAGCTTAACGATAGACG
GGGCGTTAACCCAAGCGGGTCATATTGAGTTAATGATCTATAATCCGCAGACGATTCTAGAAGAATTACAACGCTTTACT
ACCTTAGAAGACGGCGATATTGTGATGACGGGCACCCCAAAAGGCGTCGGCATCATTCCACCGAATCGCGTATTTAAGGT
GGCCTTAGGCCTTAAGGATGCGCCACACCAAACGCCCTTGGTCGAATGTGAATGGCAAAGCCGGTAA

Upstream 100 bases:

>100_bases
AAATTGCCAACGAACAACTCGATGAATTTTTAATGGAATACGCCTGATATTTACTGTGCCTTAGCTTTACTGCCAATAGC
GTAGCGTAATGAGGAGTCAA

Downstream 100 bases:

>100_bases
TGAAATGACTGTGCACTCTGCATCGACTCATCAGGCGGAAACTGAGCAGGCAATCCAACCCCTTTGGCAATATTTACTTG
CTTTAGGGGCCGAGCCCGAG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKTVNVGDKQICPSKILCIGRNYVDHIHELGNDIPEDMVVFFKPNSAISTVLHAEHLGETLHYETELCFIYQQGRFSHVG
VGLDLTKRELQSKLKTKGLPWEKAKAFDGAALFSPFVAIDDASAAFEFSLTIDGALTQAGHIELMIYNPQTILEELQRFT
TLEDGDIVMTGTPKGVGIIPPNRVFKVALGLKDAPHQTPLVECEWQSR

Sequences:

>Translated_208_residues
MKTVNVGDKQICPSKILCIGRNYVDHIHELGNDIPEDMVVFFKPNSAISTVLHAEHLGETLHYETELCFIYQQGRFSHVG
VGLDLTKRELQSKLKTKGLPWEKAKAFDGAALFSPFVAIDDASAAFEFSLTIDGALTQAGHIELMIYNPQTILEELQRFT
TLEDGDIVMTGTPKGVGIIPPNRVFKVALGLKDAPHQTPLVECEWQSR
>Mature_208_residues
MKTVNVGDKQICPSKILCIGRNYVDHIHELGNDIPEDMVVFFKPNSAISTVLHAEHLGETLHYETELCFIYQQGRFSHVG
VGLDLTKRELQSKLKTKGLPWEKAKAFDGAALFSPFVAIDDASAAFEFSLTIDGALTQAGHIELMIYNPQTILEELQRFT
TLEDGDIVMTGTPKGVGIIPPNRVFKVALGLKDAPHQTPLVECEWQSR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI66348062, Length=207, Percent_Identity=33.8164251207729, Blast_Score=111, Evalue=4e-25,
Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=34.2391304347826, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI13654274, Length=184, Percent_Identity=34.2391304347826, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI156231349, Length=192, Percent_Identity=27.0833333333333, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI40786394, Length=192, Percent_Identity=26.0416666666667, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1787428, Length=181, Percent_Identity=36.4640883977901, Blast_Score=116, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=198, Percent_Identity=35.8585858585859, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324161, Length=215, Percent_Identity=32.093023255814, Blast_Score=105, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28571789, Length=206, Percent_Identity=26.2135922330097, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23093; Mature: 23093

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVNVGDKQICPSKILCIGRNYVDHIHELGNDIPEDMVVFFKPNSAISTVLHAEHLGET
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCHH
LHYETELCFIYQQGRFSHVGVGLDLTKRELQSKLKTKGLPWEKAKAFDGAALFSPFVAID
HEECEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DASAAFEFSLTIDGALTQAGHIELMIYNPQTILEELQRFTTLEDGDIVMTGTPKGVGIIP
CCCCEEEEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEECCCCCEEECC
PNRVFKVALGLKDAPHQTPLVECEWQSR
CCCEEEEEECCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKTVNVGDKQICPSKILCIGRNYVDHIHELGNDIPEDMVVFFKPNSAISTVLHAEHLGET
CCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCHH
LHYETELCFIYQQGRFSHVGVGLDLTKRELQSKLKTKGLPWEKAKAFDGAALFSPFVAID
HEECEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DASAAFEFSLTIDGALTQAGHIELMIYNPQTILEELQRFTTLEDGDIVMTGTPKGVGIIP
CCCCEEEEEEEECCCCCCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEECCCCCEEECC
PNRVFKVALGLKDAPHQTPLVECEWQSR
CCCEEEEEECCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]