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The map label for this gene is ptsG [H]

Identifier: 117921263

GI number: 117921263

Start: 3370959

End: 3372317

Strand: Reverse

Name: ptsG [H]

Synonym: Shewana3_2822

Alternate gene names: 117921263

Gene position: 3372317-3370959 (Counterclockwise)

Preceding gene: 117921264

Following gene: 117921262

Centisome position: 67.82

GC content: 53.2

Gene sequence:

>1359_bases
TTGCCCGCAGCGGGTGTGATGCTGGGCCTAACCGTGAGTCCAATCCCTTTTATGCCCGAGGTGCTAACCGTATTAATGCT
GGCGGTTGGCAAACTGATTTTCGCCATCATGCCCATTTTGTTCGCGGTAGCTGTGGCGATAGGGTTTTGCCGCGATCAAG
GCATCGCCGCTTTTACTGCCGTATTTGGTTATGGGGTGATGACGGCCACCTTAGCCGCATTAGCGGATCTCTACCAACTG
CCGACCCAATTACTACTCGGCATGGAAACCTTAGACACTGGGATTGCCGGTGGCATGTTGATTGGTGGCGTGACTTGCTT
TGCCGTGCGCTGGAGCCAATATATTCGCCTGCCAGCGATTTTCTCCTTTTTCGAAGGGCGACGTAGCGCCTCTTTATTGA
TCATTCCGTTGGCGATGGGCTTAGGTTATATCCTTGCCCATGTGTGGCCGCCGTTATCTCTGCTCATCGAGCGGGTTTCC
GACTGGGCGGTTTACCAAAAGCCGGCCATCGCCTTTGGGGTCTATGGCGCGCTCGAACGTTTACTCATACCCCTCGGTTT
ACATCATATCTGGAATGCACCTTTCTATTTAGAAGTCGGCCAATACCAGTTACAGAATTCGGAAGTGGTTCGGGGGGAAG
TTGCGCGTTATTTAGCTGGCGATCCGCAGGCGGGGAATTTAGCGGGCGGTTATTTGATAAAAATGTGGGGACTCCCCGCA
GCGGCGCTAGCCATATGGCGCTGCGCCGAACCCTCGGAGCGTAATCGGGTCGCGGGTATTATGCTTTCCGCGGCGGCGGC
CAGTTGGCTGACCGGAGTCACAGAGCCTATCGAGTTCGCCTTTATGTTTGTGGCGCCATTTTTGTTTCTTATCCATGTGC
TGCTGTCGGGGCTGGCATATTTTGTCTGCATCATGCTCGATATTCACCACAGTATTGTGTTCTCCCATGGGCTGGTGGAT
TTCACGCTGCTGTTTTCGCTGTCGCGCAATACGGGTTGGTTCGTATTCTTAGGGCCGCTGACGGCGGTGATTTATTATCT
GCTGTTTAGGGGCAGTATTCTGGCATTTAATTTAAAGACGCCAGGACGACTCGAACCCGATGAACCCCATGGTGCCAAAG
AGAGCTTAAGGGCCATCATTGCGGCATTGGGCGGTCGTGAGAATATTGTCGAGCTCAATGCTTGTCTCACCCGTTTACGC
TTGAGTGTGCACAGCCCAGAACTCGTCAATAAAGTGCGGCTCAGCCAGCTCGGTGCTAAGGGCGTGATTGTGATGGGCAA
AGGTGTGCAAGTGGTATATGGCACTAAGGCCGAAACCCTACGCAAAGTCTTGCAGCGTTATTTAGATACTCGGCGCTGA

Upstream 100 bases:

>100_bases
TCGTCAAATCCGAACGCGCCGCTTAGGTCATTTCGTTACTCAGCAGTGGTTTAAATTTGCCCAGCGCTTAAGTCAGGCGC
TGTTAATTCCGATTGCGATT

Downstream 100 bases:

>100_bases
TATTGCATCTTGTTGAAATTAATCGCTGCTTTATTGTGTTTAATAAAGTTAACTCACAATAAATTCACTTTTTATCACAA
AAAATAAGCTTTTCATGCTG

Product: PTS system, glucose-like IIB subunit

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MPAAGVMLGLTVSPIPFMPEVLTVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYQL
PTQLLLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAMGLGYILAHVWPPLSLLIERVS
DWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEVGQYQLQNSEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPA
AALAIWRCAEPSERNRVAGIMLSAAAASWLTGVTEPIEFAFMFVAPFLFLIHVLLSGLAYFVCIMLDIHHSIVFSHGLVD
FTLLFSLSRNTGWFVFLGPLTAVIYYLLFRGSILAFNLKTPGRLEPDEPHGAKESLRAIIAALGGRENIVELNACLTRLR
LSVHSPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKAETLRKVLQRYLDTRR

Sequences:

>Translated_452_residues
MPAAGVMLGLTVSPIPFMPEVLTVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYQL
PTQLLLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAMGLGYILAHVWPPLSLLIERVS
DWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEVGQYQLQNSEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPA
AALAIWRCAEPSERNRVAGIMLSAAAASWLTGVTEPIEFAFMFVAPFLFLIHVLLSGLAYFVCIMLDIHHSIVFSHGLVD
FTLLFSLSRNTGWFVFLGPLTAVIYYLLFRGSILAFNLKTPGRLEPDEPHGAKESLRAIIAALGGRENIVELNACLTRLR
LSVHSPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKAETLRKVLQRYLDTRR
>Mature_451_residues
PAAGVMLGLTVSPIPFMPEVLTVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYQLP
TQLLLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAMGLGYILAHVWPPLSLLIERVSD
WAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEVGQYQLQNSEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAA
ALAIWRCAEPSERNRVAGIMLSAAAASWLTGVTEPIEFAFMFVAPFLFLIHVLLSGLAYFVCIMLDIHHSIVFSHGLVDF
TLLFSLSRNTGWFVFLGPLTAVIYYLLFRGSILAFNLKTPGRLEPDEPHGAKESLRAIIAALGGRENIVELNACLTRLRL
SVHSPELVNKVRLSQLGAKGVIVMGKGVQVVYGTKAETLRKVLQRYLDTRR

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=455, Percent_Identity=43.956043956044, Blast_Score=413, Evalue=1e-116,
Organism=Escherichia coli, GI1786894, Length=452, Percent_Identity=35.3982300884956, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1787908, Length=470, Percent_Identity=33.4042553191489, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49280; Mature: 49149

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAGVMLGLTVSPIPFMPEVLTVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTA
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VFGYGVMTATLAALADLYQLPTQLLLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FSFFEGRRSASLLIIPLAMGLGYILAHVWPPLSLLIERVSDWAVYQKPAIAFGVYGALER
HHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLIPLGLHHIWNAPFYLEVGQYQLQNSEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPA
HHHHHHHHHHHCCCEEEEECCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCH
AALAIWRCAEPSERNRVAGIMLSAAAASWLTGVTEPIEFAFMFVAPFLFLIHVLLSGLAY
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVCIMLDIHHSIVFSHGLVDFTLLFSLSRNTGWFVFLGPLTAVIYYLLFRGSILAFNLKT
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCC
PGRLEPDEPHGAKESLRAIIAALGGRENIVELNACLTRLRLSVHSPELVNKVRLSQLGAK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GVIVMGKGVQVVYGTKAETLRKVLQRYLDTRR
CEEEECCCEEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAAGVMLGLTVSPIPFMPEVLTVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTA
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VFGYGVMTATLAALADLYQLPTQLLLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FSFFEGRRSASLLIIPLAMGLGYILAHVWPPLSLLIERVSDWAVYQKPAIAFGVYGALER
HHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLIPLGLHHIWNAPFYLEVGQYQLQNSEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPA
HHHHHHHHHHHCCCEEEEECCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCH
AALAIWRCAEPSERNRVAGIMLSAAAASWLTGVTEPIEFAFMFVAPFLFLIHVLLSGLAY
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVCIMLDIHHSIVFSHGLVDFTLLFSLSRNTGWFVFLGPLTAVIYYLLFRGSILAFNLKT
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCEEEEECCC
PGRLEPDEPHGAKESLRAIIAALGGRENIVELNACLTRLRLSVHSPELVNKVRLSQLGAK
CCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
GVIVMGKGVQVVYGTKAETLRKVLQRYLDTRR
CEEEECCCEEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]