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The map label for this gene is cysQ [H]

Identifier: 117921232

GI number: 117921232

Start: 3330984

End: 3331790

Strand: Reverse

Name: cysQ [H]

Synonym: Shewana3_2791

Alternate gene names: 117921232

Gene position: 3331790-3330984 (Counterclockwise)

Preceding gene: 117921233

Following gene: 117921231

Centisome position: 67.01

GC content: 50.31

Gene sequence:

>807_bases
GTGACAGATAATACAGTGATGGCAGCGCATTTTTCGAAGGCCGATTTACTGCGGGTGGTAAAGATTGCCCATGCGGCAGG
CGACGCCATCATGGCAATTTATGCCCAAGAGGATTTTGCCGTTACGCAAAAGCGTGATGAGAGCCCGGTAACGGCGGCCG
ATTTGGTGGCTCACAAAGTTATCTTAGCCCAGCTTACCGAGCAATTTGCGGGCATTCCCGTGATGTCGGAAGAAGCGGCG
GATATCGCCTGGGATGAACGTCGGCACTGGCAGACCTATTGGCTGATTGACCCTTTGGATGGCACTAAGGAATTTATTAA
GCGAAATGGTGAGTTTACCGTCAATATTGCGCTTATCCATCAAGGTGTGGCTATTGCTGGTGTGGTTTATGCTCCCGTAC
TCAATACCGTTTATTTTGGCGCCAAACACTTAGGCGCTTGGCGACAGGATGGGCAACAAGAGCTAGTGCTACAGGGCTGT
AATACGCCAAGGCAAATACCGATAGTGGTGGGTAGTCGTTCGCACTTAAGCCCTGATGTGGCGGAATATTTAAAGGATTT
CGGTCAACACGAGATGTTAAGCGTGGGAAGCTCGCTGAAGTTTTGTATGTTGGCAGAGGGCAAGGCCGATCTCTATCCAA
GATTAGGGCCTACGAGCGAATGGGATACGGCAGCCGCGCAGGCCGTGCTGGAAAGCGCAGGCGGCAAAGTTGTGTGTTAT
GACTCAGGTTTACCCTTAACCTACAATCAAAAACCTGACATATTAAACCCTTATTTTATTGCCACGGCACCAGGCTGGGC
AGAATAA

Upstream 100 bases:

>100_bases
GCCTTAGTCGATTTTGCTCGATATATGATGAATTTGTTCTTAATTATCAATTGCTGCCAGTGGCATAATGCCGAAAAGCA
AATCGAATACAGGTGGCTAA

Downstream 100 bases:

>100_bases
CGAACAATGCCAAGGGCATCTGTACTGACGCCTTGGTCGAATAACAGTGGAGTAAGTCATTCATGATACGCATGGGCATC
GATTTAGGTGGCACAAAAAT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTDNTVMAAHFSKADLLRVVKIAHAAGDAIMAIYAQEDFAVTQKRDESPVTAADLVAHKVILAQLTEQFAGIPVMSEEAA
DIAWDERRHWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLNTVYFGAKHLGAWRQDGQQELVLQGC
NTPRQIPIVVGSRSHLSPDVAEYLKDFGQHEMLSVGSSLKFCMLAEGKADLYPRLGPTSEWDTAAAQAVLESAGGKVVCY
DSGLPLTYNQKPDILNPYFIATAPGWAE

Sequences:

>Translated_268_residues
MTDNTVMAAHFSKADLLRVVKIAHAAGDAIMAIYAQEDFAVTQKRDESPVTAADLVAHKVILAQLTEQFAGIPVMSEEAA
DIAWDERRHWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLNTVYFGAKHLGAWRQDGQQELVLQGC
NTPRQIPIVVGSRSHLSPDVAEYLKDFGQHEMLSVGSSLKFCMLAEGKADLYPRLGPTSEWDTAAAQAVLESAGGKVVCY
DSGLPLTYNQKPDILNPYFIATAPGWAE
>Mature_267_residues
TDNTVMAAHFSKADLLRVVKIAHAAGDAIMAIYAQEDFAVTQKRDESPVTAADLVAHKVILAQLTEQFAGIPVMSEEAAD
IAWDERRHWQTYWLIDPLDGTKEFIKRNGEFTVNIALIHQGVAIAGVVYAPVLNTVYFGAKHLGAWRQDGQQELVLQGCN
TPRQIPIVVGSRSHLSPDVAEYLKDFGQHEMLSVGSSLKFCMLAEGKADLYPRLGPTSEWDTAAAQAVLESAGGKVVCYD
SGLPLTYNQKPDILNPYFIATAPGWAE

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=29.957805907173, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116812595, Length=260, Percent_Identity=28.0769230769231, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI5031789, Length=223, Percent_Identity=26.0089686098655, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI221625487, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=50.3968253968254, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1788882, Length=229, Percent_Identity=27.0742358078603, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537869, Length=310, Percent_Identity=25.4838709677419, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=244, Percent_Identity=25.8196721311475, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651149, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29328; Mature: 29196

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNTVMAAHFSKADLLRVVKIAHAAGDAIMAIYAQEDFAVTQKRDESPVTAADLVAHKV
CCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHH
ILAQLTEQFAGIPVMSEEAADIAWDERRHWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLNTVYFGAKHLGAWRQDGQQELVLQGCNTPRQIPIVVGSRSHLSPDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCHHH
AEYLKDFGQHEMLSVGSSLKFCMLAEGKADLYPRLGPTSEWDTAAAQAVLESAGGKVVCY
HHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
DSGLPLTYNQKPDILNPYFIATAPGWAE
ECCCCEEECCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
TDNTVMAAHFSKADLLRVVKIAHAAGDAIMAIYAQEDFAVTQKRDESPVTAADLVAHKV
CCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCCCCHHHHHHHHHH
ILAQLTEQFAGIPVMSEEAADIAWDERRHWQTYWLIDPLDGTKEFIKRNGEFTVNIALIH
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEEEEEEECCCCHHHHHHCCCCEEEEEEEEE
QGVAIAGVVYAPVLNTVYFGAKHLGAWRQDGQQELVLQGCNTPRQIPIVVGSRSHLSPDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCHHH
AEYLKDFGQHEMLSVGSSLKFCMLAEGKADLYPRLGPTSEWDTAAAQAVLESAGGKVVCY
HHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
DSGLPLTYNQKPDILNPYFIATAPGWAE
ECCCCEEECCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]