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The map label for this gene is galE [H]

Identifier: 117921224

GI number: 117921224

Start: 3322413

End: 3323426

Strand: Direct

Name: galE [H]

Synonym: Shewana3_2783

Alternate gene names: 117921224

Gene position: 3322413-3323426 (Clockwise)

Preceding gene: 117921223

Following gene: 117921225

Centisome position: 66.82

GC content: 48.13

Gene sequence:

>1014_bases
ATGACGATTTTAGTGACCGGAGGCGCCGGTTATATCGGCACTCATACCGTAGTGGAATTACTCAATGCGGGGAGTGAAGT
GATTGTATTAGACAACCTGTCTAATTCAAGCATCGAAGCCCTTAACCGTGTCGAGCGCATTACCGGCAAAGCGGTCACTT
TTTACCAAGGCGATATTCTCAACAAGGCCTTACTGCAGAAAGTCTTTAGCGACCATAACATCGATGCTGTTATCCATTTT
GCAGGATTAAAAGCCGTTGGTGAGTCAGTCGCTAAACCGCTGAAATACTATGAGAATAACGTGACTGGCACCTTAATTCT
TTGCCAAGTGATGGCAGAGTTTAAGGTGAAAAACCTCGTCTTTAGTTCTTCTGCTACTGTGTATGGCGACCCTGCCAGCC
TACCGATTACCGAAGATTTTCCCACGGGCGCCACTAACCCCTACGGTCAATCTAAGTTGATGGTGGAGCATATACTGGCG
GATTTACACCATAGCGATCCGAGTTGGAATATCGCCCGTTTACGTTACTTCAACCCTGTTGGCGCCCATGCCAGCGGCTT
GATTGGCGAAGATCCTAACGATATTCCAAATAACTTGATGCCATTTATCGCGCAGGTAGCAGTCGGTAAACGCGAAGCGT
TAAGTGTGTTTGGCAATGATTATCCAACCCACGATGGTACTGGCGTTCGCGACTATATCCACGTGGTGGATTTAGCCCTT
GGACACCTCAAAGCCATTGAAAAACTGACCACTAAACCAGGACTTGTCACCTATAACCTAGGTACAGGCCAAGGCTACAG
TGTGCTCGATATGGTCAAGGCCTTTGAAAAGGCCTGTGGTAAGTCGATTGCCTATCAAATTGCGCCGCGTCGTCCAGGCG
ACATTGCCGCCTGCTATGCAAACCCAGATCATGCTAAAACCGATCTGGGCTGGCAGGCGACTCACAGCCTAGAAGATATG
GCGAACAGCAGTTGGCATTGGCAATCAACCAATCCAAATGGTTATAAAGGCTAA

Upstream 100 bases:

>100_bases
AAGGCTATATGCGCGCTAACGTGGAATACGCCCTGCGCCACAGCGAAATCGGTGAAGATTTTGCGCAATATTTAAAAACA
GTCGTAAAAGGAATTAAATA

Downstream 100 bases:

>100_bases
GCGTCTAAATGGCTTGCGGTAACTCCCAAGCCATTTTTATTATCCCTTATCACAATTAAACTCCGTAAGACCTATGACAG
AAAGCATCAATCACAGCCGC

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTILVTGGAGYIGTHTVVELLNAGSEVIVLDNLSNSSIEALNRVERITGKAVTFYQGDILNKALLQKVFSDHNIDAVIHF
AGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DLHHSDPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKREALSVFGNDYPTHDGTGVRDYIHVVDLAL
GHLKAIEKLTTKPGLVTYNLGTGQGYSVLDMVKAFEKACGKSIAYQIAPRRPGDIAACYANPDHAKTDLGWQATHSLEDM
ANSSWHWQSTNPNGYKG

Sequences:

>Translated_337_residues
MTILVTGGAGYIGTHTVVELLNAGSEVIVLDNLSNSSIEALNRVERITGKAVTFYQGDILNKALLQKVFSDHNIDAVIHF
AGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILA
DLHHSDPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKREALSVFGNDYPTHDGTGVRDYIHVVDLAL
GHLKAIEKLTTKPGLVTYNLGTGQGYSVLDMVKAFEKACGKSIAYQIAPRRPGDIAACYANPDHAKTDLGWQATHSLEDM
ANSSWHWQSTNPNGYKG
>Mature_336_residues
TILVTGGAGYIGTHTVVELLNAGSEVIVLDNLSNSSIEALNRVERITGKAVTFYQGDILNKALLQKVFSDHNIDAVIHFA
GLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLVFSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILAD
LHHSDPSWNIARLRYFNPVGAHASGLIGEDPNDIPNNLMPFIAQVAVGKREALSVFGNDYPTHDGTGVRDYIHVVDLALG
HLKAIEKLTTKPGLVTYNLGTGQGYSVLDMVKAFEKACGKSIAYQIAPRRPGDIAACYANPDHAKTDLGWQATHSLEDMA
NSSWHWQSTNPNGYKG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=59.4117647058824, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=59.4117647058824, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=59.4117647058824, Blast_Score=420, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=28.7272727272727, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI42516563, Length=331, Percent_Identity=24.4712990936556, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=61.9047619047619, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI48994969, Length=378, Percent_Identity=26.984126984127, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788353, Length=366, Percent_Identity=25.1366120218579, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=54.2028985507246, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=53.8904899135447, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=25.5952380952381, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=52.4781341107872, Blast_Score=370, Evalue=1e-103,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=59.7667638483965, Blast_Score=422, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36439; Mature: 36307

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVTGGAGYIGTHTVVELLNAGSEVIVLDNLSNSSIEALNRVERITGKAVTFYQGDIL
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHH
NKALLQKVFSDHNIDAVIHFAGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLV
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADLHHSDPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKREALSVFGNDYPTHDGTGVRDYIHVVDLAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GHLKAIEKLTTKPGLVTYNLGTGQGYSVLDMVKAFEKACGKSIAYQIAPRRPGDIAACYA
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
NPDHAKTDLGWQATHSLEDMANSSWHWQSTNPNGYKG
CCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCC
>Mature Secondary Structure 
TILVTGGAGYIGTHTVVELLNAGSEVIVLDNLSNSSIEALNRVERITGKAVTFYQGDIL
EEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHH
NKALLQKVFSDHNIDAVIHFAGLKAVGESVAKPLKYYENNVTGTLILCQVMAEFKVKNLV
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHE
FSSSATVYGDPASLPITEDFPTGATNPYGQSKLMVEHILADLHHSDPSWNIARLRYFNPV
EECCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GAHASGLIGEDPNDIPNNLMPFIAQVAVGKREALSVFGNDYPTHDGTGVRDYIHVVDLAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GHLKAIEKLTTKPGLVTYNLGTGQGYSVLDMVKAFEKACGKSIAYQIAPRRPGDIAACYA
HHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEC
NPDHAKTDLGWQATHSLEDMANSSWHWQSTNPNGYKG
CCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]