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The map label for this gene is hmrR2 [H]

Identifier: 117921203

GI number: 117921203

Start: 3300537

End: 3300926

Strand: Direct

Name: hmrR2 [H]

Synonym: Shewana3_2762

Alternate gene names: 117921203

Gene position: 3300537-3300926 (Clockwise)

Preceding gene: 117921200

Following gene: 117921215

Centisome position: 66.38

GC content: 49.23

Gene sequence:

>390_bases
ATGAAAATTGGTGAAGTCGCGAAACACACAGGATTAAGCGTTAAAAGCATACGCTATTACCACGATATCGGCCTTGTCTG
CGGCGAGCGTAACGAGGCGGGATACAGGGTCTATCGCCATCGGGATATCGAATCGCTGAAATTTGTCCACCAGTGCCGCG
ACTTAGGTTTTAGTCTCGAGGATTGCAAACTCTTGCTTGGCCTTCGCAATAACGATAGCCGCAATGCCGAAGATGTGAAG
CAACTCACCCGCAACCATTTGGCCTATGTCGAGGAGCAAATTGGTAAATTGCAGAATCTTCGTAGCCAGTTACAGCAAAT
GGTCAGCGAGTGCCAAGGTGGCGAGCAGCCTCACTGCGCCATTATTGATAGCCTTAATCACCAGCACTAA

Upstream 100 bases:

>100_bases
TAAGATAAAGTCTCCCATCACGGGAGAGTCAAGGGTGTTTTTGTGGCAAGTATCACACTTGTCTGCATGAGTCTTTAGAA
CAGATAAAACCGAGGTCAGT

Downstream 100 bases:

>100_bases
ATGCTTAATCATCTGCATTAACACGCAGTTATAAAAAAGCCTGCTTGGATGCAGGCTTTTTTATGGGGTTATCGCGAGCT
CAGAGGCGTTATCACCAAGA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MKIGEVAKHTGLSVKSIRYYHDIGLVCGERNEAGYRVYRHRDIESLKFVHQCRDLGFSLEDCKLLLGLRNNDSRNAEDVK
QLTRNHLAYVEEQIGKLQNLRSQLQQMVSECQGGEQPHCAIIDSLNHQH

Sequences:

>Translated_129_residues
MKIGEVAKHTGLSVKSIRYYHDIGLVCGERNEAGYRVYRHRDIESLKFVHQCRDLGFSLEDCKLLLGLRNNDSRNAEDVK
QLTRNHLAYVEEQIGKLQNLRSQLQQMVSECQGGEQPHCAIIDSLNHQH
>Mature_129_residues
MKIGEVAKHTGLSVKSIRYYHDIGLVCGERNEAGYRVYRHRDIESLKFVHQCRDLGFSLEDCKLLLGLRNNDSRNAEDVK
QLTRNHLAYVEEQIGKLQNLRSQLQQMVSECQGGEQPHCAIIDSLNHQH

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=39.3700787401575, Blast_Score=96, Evalue=8e-22,
Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=33.0769230769231, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14844; Mature: 14844

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGEVAKHTGLSVKSIRYYHDIGLVCGERNEAGYRVYRHRDIESLKFVHQCRDLGFSLE
CCCCHHHHHCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHH
DCKLLLGLRNNDSRNAEDVKQLTRNHLAYVEEQIGKLQNLRSQLQQMVSECQGGEQPHCA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IIDSLNHQH
HHHCCCCCC
>Mature Secondary Structure
MKIGEVAKHTGLSVKSIRYYHDIGLVCGERNEAGYRVYRHRDIESLKFVHQCRDLGFSLE
CCCCHHHHHCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHH
DCKLLLGLRNNDSRNAEDVKQLTRNHLAYVEEQIGKLQNLRSQLQQMVSECQGGEQPHCA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
IIDSLNHQH
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]