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The map label for this gene is aaeR [H]

Identifier: 117921163

GI number: 117921163

Start: 3253167

End: 3254054

Strand: Reverse

Name: aaeR [H]

Synonym: Shewana3_2722

Alternate gene names: 117921163

Gene position: 3254054-3253167 (Counterclockwise)

Preceding gene: 117921172

Following gene: 117921161

Centisome position: 65.44

GC content: 47.97

Gene sequence:

>888_bases
ATGAAACCTAACTATTCGTTGGACGATCTGCGCTGTTTTTGTGCTGTGGCACGTTCTGGCAGCTTTAAGGAGGCCGCCCA
ATCCTTAGGTATGCCGCTCTCAACCTTGAGCCGCCGTATCCGCCAGCTAGAGACCGATTTGCAATTAAGATTGCTTAATC
GAGACGCCCACCGCGTCATCTTAACCAGCATCGGTGAGCAGTATTTTGAGCGCTCGGTAGCCCTGTTTGATGAACTCAAT
AATATTGACGAAGATTTGCATCGGGATAAGTACCAGCCACAGGGGAAAATCCGCATTTCCGCGCCCATCAACTCTGGCAC
TCATTTTCTGCGGTCGATTTTTTATGATTTTCTGCTGCAATATCCCGATATTCAGTTGGATTTGAGCTTTTCAAACTCGC
TTATTGATATTGAAGCGGAAGGCATGGATGTGGCGTTTAGAGTGGGCAATCCTGTGGTGGAAAATTGGATTGCCAGACCG
TTAAAGCATATTCACTTTATTTTGTGCTCTCACCCTGACTACGACATTTCGAGCATCACTACGCCAGACAAGTTATGCGG
TCACCCAACCATTATTTGCCACCCTATGATTCCTTGGCAATTGGTGCATAAAACGACTGGCGAAGAGTTTGATTATCACC
CGAACAAGGGCGTCAGGCTGGAGGTGGATGAACTCATGCTACTGACCCACGCCATCAAAACAGGGATAGGTATCGGATAC
GTGCCGGATTATTTTGCACTACCTATGATAGCGCAGGGGGAGGTGAATCATGTTCTCCCTGAATGGAGTAGCAAAGCCCG
CACCTTGTCCATGTTATATCGGGACCGCGACCATCTCCCCATGCGGGTGCGGTTGTTTATCGAGTTTGTGAAATTGCACT
TTAACTAG

Upstream 100 bases:

>100_bases
ATTTCATCGCCACTCCAGATGACTTGTTAAATACTGAGCCTTAGTGTATTGATTTCAATAATTGGATAAACAAGCAAAAG
TAAGACGGTAAATACCAATA

Downstream 100 bases:

>100_bases
GGCTCGCGTTATTCCGCCAGCCAAGGAACACCGACATTTGAGCGCGTTGGGTTTATAGCGCGCAGGCGGGCAGATATTCG
GATAATTCCAATAGATTCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MKPNYSLDDLRCFCAVARSGSFKEAAQSLGMPLSTLSRRIRQLETDLQLRLLNRDAHRVILTSIGEQYFERSVALFDELN
NIDEDLHRDKYQPQGKIRISAPINSGTHFLRSIFYDFLLQYPDIQLDLSFSNSLIDIEAEGMDVAFRVGNPVVENWIARP
LKHIHFILCSHPDYDISSITTPDKLCGHPTIICHPMIPWQLVHKTTGEEFDYHPNKGVRLEVDELMLLTHAIKTGIGIGY
VPDYFALPMIAQGEVNHVLPEWSSKARTLSMLYRDRDHLPMRVRLFIEFVKLHFN

Sequences:

>Translated_295_residues
MKPNYSLDDLRCFCAVARSGSFKEAAQSLGMPLSTLSRRIRQLETDLQLRLLNRDAHRVILTSIGEQYFERSVALFDELN
NIDEDLHRDKYQPQGKIRISAPINSGTHFLRSIFYDFLLQYPDIQLDLSFSNSLIDIEAEGMDVAFRVGNPVVENWIARP
LKHIHFILCSHPDYDISSITTPDKLCGHPTIICHPMIPWQLVHKTTGEEFDYHPNKGVRLEVDELMLLTHAIKTGIGIGY
VPDYFALPMIAQGEVNHVLPEWSSKARTLSMLYRDRDHLPMRVRLFIEFVKLHFN
>Mature_295_residues
MKPNYSLDDLRCFCAVARSGSFKEAAQSLGMPLSTLSRRIRQLETDLQLRLLNRDAHRVILTSIGEQYFERSVALFDELN
NIDEDLHRDKYQPQGKIRISAPINSGTHFLRSIFYDFLLQYPDIQLDLSFSNSLIDIEAEGMDVAFRVGNPVVENWIARP
LKHIHFILCSHPDYDISSITTPDKLCGHPTIICHPMIPWQLVHKTTGEEFDYHPNKGVRLEVDELMLLTHAIKTGIGIGY
VPDYFALPMIAQGEVNHVLPEWSSKARTLSMLYRDRDHLPMRVRLFIEFVKLHFN

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=26.7558528428094, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.7966101694915, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786401, Length=302, Percent_Identity=29.4701986754967, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=28.135593220339, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=28.719723183391, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=25.8620689655172, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=27.3037542662116, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788748, Length=263, Percent_Identity=30.0380228136882, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=23.1292517006803, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787879, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=128, Percent_Identity=27.34375, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=32.7586206896552, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34018; Mature: 34018

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNYSLDDLRCFCAVARSGSFKEAAQSLGMPLSTLSRRIRQLETDLQLRLLNRDAHRVI
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCHHHHH
LTSIGEQYFERSVALFDELNNIDEDLHRDKYQPQGKIRISAPINSGTHFLRSIFYDFLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHC
YPDIQLDLSFSNSLIDIEAEGMDVAFRVGNPVVENWIARPLKHIHFILCSHPDYDISSIT
CCCEEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
TPDKLCGHPTIICHPMIPWQLVHKTTGEEFDYHPNKGVRLEVDELMLLTHAIKTGIGIGY
CCHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCC
VPDYFALPMIAQGEVNHVLPEWSSKARTLSMLYRDRDHLPMRVRLFIEFVKLHFN
CCHHHHCCEECCCCHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPNYSLDDLRCFCAVARSGSFKEAAQSLGMPLSTLSRRIRQLETDLQLRLLNRDAHRVI
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCHHHHH
LTSIGEQYFERSVALFDELNNIDEDLHRDKYQPQGKIRISAPINSGTHFLRSIFYDFLLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHC
YPDIQLDLSFSNSLIDIEAEGMDVAFRVGNPVVENWIARPLKHIHFILCSHPDYDISSIT
CCCEEEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCC
TPDKLCGHPTIICHPMIPWQLVHKTTGEEFDYHPNKGVRLEVDELMLLTHAIKTGIGIGY
CCHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCC
VPDYFALPMIAQGEVNHVLPEWSSKARTLSMLYRDRDHLPMRVRLFIEFVKLHFN
CCHHHHCCEECCCCHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]