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The map label for this gene is sapC [H]

Identifier: 117921093

GI number: 117921093

Start: 3165894

End: 3166784

Strand: Direct

Name: sapC [H]

Synonym: Shewana3_2652

Alternate gene names: 117921093

Gene position: 3165894-3166784 (Clockwise)

Preceding gene: 117921092

Following gene: 117921094

Centisome position: 63.67

GC content: 51.52

Gene sequence:

>891_bases
ATGCCTCCAATTAAAATTTATCAGGAAGATCAAATCGCCTCGCCGATGATGCGGGTCTGGCAGAATTTTTCGGCAAACCC
CTTTGCCTTAGCGGGTTTGTGGACCATTGCTTTTCTGCTGCTGCTCACCCTGTTCGGACCTATGATTGCCCCTTTCTCCC
CCGAAGCGCAGGATCCTCGCGCATTACTGTTGCCGCCCTCTTGGGACCCATCGGGCACAGTGGCGCACTTTTTAGGTACT
GATGATCTGGGTCGTGACATTTTTAGCCGCTTACTGCATGGGGCGCATTTAACCTTCGGCATGGCGCTAATGATTGTCGG
CACCGCGCTGTTTATGGGTTTCATCATAGGCTCGCTTTCGGGCATGATGCGCGGCTTAAAGTCCAGTATCTTGGGGCACT
TACTCGATGCATTGCTGTCGATTCCTTCACTATTAATGGCGATTTTAGTGGTTGCAGTGATGGGGCCAGGGCTTGAAAAC
GTCTTCTGGGCCGTGGGCATTGCCTTAACACCGCAGTTTGTGCGCTCCATTCATCAATCGGTGCATGAAGAGTTACAGAA
AGAATACGTAACTGCCGCCCGTTTAGACGGCGCCAATTCGCTGCAGATTTTTTGGTATGTGATCATGCCAAACGTGTGGG
AAGTAGTGATTATTCAAACCACCTTAGCCATTTCTGCCGCGATTTTAGATATTGCCGCCCTTGGCTTTTTAAGCCTTGGC
GCCCAAGCTCCCAGCCCTGAATGGGGTGCAATGGTCGCCCAAGGCATGGATAATTTGTTGACCGCACCTTGGACTGTGAC
CATTCCAGGGCTGGCGATTCTTTTTAGTGTGCTCGCCATTAACTTGGTGGGCGATGGCTTGAGATCGGCGCTTGCGCCCA
TCAGAAACTAA

Upstream 100 bases:

>100_bases
CAAGGCGGGATTTTAGCCGTGGCCTTGTTGATCATCTTTTTAAGTATTTTGATTGAAGTGCTGCATACCGTCTTCAATCC
CTTGAGCAGAAAAGATCTTT

Downstream 100 bases:

>100_bases
CCTATGCCATTACTCGACGTTAGAAACCTGACCATTGAGCTCGACACGCCCCACGGCAGAGTGCGCGCCCTTGAGAAAGT
GAGTTTGACCCTGAACGCGG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPPIKIYQEDQIASPMMRVWQNFSANPFALAGLWTIAFLLLLTLFGPMIAPFSPEAQDPRALLLPPSWDPSGTVAHFLGT
DDLGRDIFSRLLHGAHLTFGMALMIVGTALFMGFIIGSLSGMMRGLKSSILGHLLDALLSIPSLLMAILVVAVMGPGLEN
VFWAVGIALTPQFVRSIHQSVHEELQKEYVTAARLDGANSLQIFWYVIMPNVWEVVIIQTTLAISAAILDIAALGFLSLG
AQAPSPEWGAMVAQGMDNLLTAPWTVTIPGLAILFSVLAINLVGDGLRSALAPIRN

Sequences:

>Translated_296_residues
MPPIKIYQEDQIASPMMRVWQNFSANPFALAGLWTIAFLLLLTLFGPMIAPFSPEAQDPRALLLPPSWDPSGTVAHFLGT
DDLGRDIFSRLLHGAHLTFGMALMIVGTALFMGFIIGSLSGMMRGLKSSILGHLLDALLSIPSLLMAILVVAVMGPGLEN
VFWAVGIALTPQFVRSIHQSVHEELQKEYVTAARLDGANSLQIFWYVIMPNVWEVVIIQTTLAISAAILDIAALGFLSLG
AQAPSPEWGAMVAQGMDNLLTAPWTVTIPGLAILFSVLAINLVGDGLRSALAPIRN
>Mature_295_residues
PPIKIYQEDQIASPMMRVWQNFSANPFALAGLWTIAFLLLLTLFGPMIAPFSPEAQDPRALLLPPSWDPSGTVAHFLGTD
DLGRDIFSRLLHGAHLTFGMALMIVGTALFMGFIIGSLSGMMRGLKSSILGHLLDALLSIPSLLMAILVVAVMGPGLENV
FWAVGIALTPQFVRSIHQSVHEELQKEYVTAARLDGANSLQIFWYVIMPNVWEVVIIQTTLAISAAILDIAALGFLSLGA
QAPSPEWGAMVAQGMDNLLTAPWTVTIPGLAILFSVLAINLVGDGLRSALAPIRN

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=291, Percent_Identity=49.8281786941581, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=43.2142857142857, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1787760, Length=275, Percent_Identity=38.9090909090909, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1787054, Length=294, Percent_Identity=35.0340136054422, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=34.156378600823, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787498, Length=279, Percent_Identity=29.3906810035842, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31865; Mature: 31734

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPIKIYQEDQIASPMMRVWQNFSANPFALAGLWTIAFLLLLTLFGPMIAPFSPEAQDPR
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ALLLPPSWDPSGTVAHFLGTDDLGRDIFSRLLHGAHLTFGMALMIVGTALFMGFIIGSLS
EEEECCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMRGLKSSILGHLLDALLSIPSLLMAILVVAVMGPGLENVFWAVGIALTPQFVRSIHQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
VHEELQKEYVTAARLDGANSLQIFWYVIMPNVWEVVIIQTTLAISAAILDIAALGFLSLG
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQAPSPEWGAMVAQGMDNLLTAPWTVTIPGLAILFSVLAINLVGDGLRSALAPIRN
CCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PPIKIYQEDQIASPMMRVWQNFSANPFALAGLWTIAFLLLLTLFGPMIAPFSPEAQDPR
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ALLLPPSWDPSGTVAHFLGTDDLGRDIFSRLLHGAHLTFGMALMIVGTALFMGFIIGSLS
EEEECCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMRGLKSSILGHLLDALLSIPSLLMAILVVAVMGPGLENVFWAVGIALTPQFVRSIHQS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHH
VHEELQKEYVTAARLDGANSLQIFWYVIMPNVWEVVIIQTTLAISAAILDIAALGFLSLG
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQAPSPEWGAMVAQGMDNLLTAPWTVTIPGLAILFSVLAINLVGDGLRSALAPIRN
CCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]