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The map label for this gene is sapB [H]

Identifier: 117921092

GI number: 117921092

Start: 3164876

End: 3165907

Strand: Direct

Name: sapB [H]

Synonym: Shewana3_2651

Alternate gene names: 117921092

Gene position: 3164876-3165907 (Clockwise)

Preceding gene: 117921091

Following gene: 117921093

Centisome position: 63.65

GC content: 49.03

Gene sequence:

>1032_bases
ATGTTCAGATACCTGTTACGGCGCCTCAACCTGTTTCTTGCCACTTCGCTCGTGATGGTCGGCGTATTGTTTTATGCAAC
AGGGTTATTTCCTGTTGAACGCACCTTCGCCCTCACGGGTATCCATGCACCGTCAGAGAGTCAACTGGTGCAAATTGAGC
AGGACTATAAGTTAGATAGCAATAAGGCCATGCAGTTTATTGCTTATTTACAGCAAAGACTGAGCGGCAATTTGGGCGTC
TCCGTCACCTCGCACCAGAGCGTGGCCGAAGAATTAAGCTCTGTGCTACCTGCCTCCTTCGAACTTGCCGTTATGGCGGC
CGTGATTGCTATTGGTTTAGGCGTGCCGCTTGGCGTGTTGGCCTCCCAGAGCCAACATAAACTCACCCAAAACACCATTA
TGGCGATTACCCTGACGGGCTATTCCGTTCCTGTATTCTGGTTAGGTTTGTATTTGTCACTCTGGTTTGGTGTCGACCTT
GGCTGGCTACCCATTTCAGGGCAACTCAATCTCTTATATGAGATAAAACCTGTTACGGGATTTATGTTGGTCGACATTTT
GCTGTCTGATTCGGAATACCGGATATCGGCCTTTAAAGATGCCTTATTGCATATCGTCCTGCCCGCCACCACACTCGCAG
TGCTCCCTTTTACCGTGGTCGTACGCAGCACGCGCTCGGCGATGATGAATGTGATGAACCAAACCTTTATCCGCGCCGCC
GAAGCCAGAGGCATGCACACCAACACCATTATTTTGCGCCACGCCTTACCCAACGCGCTGATCCCCGTATTGAAGCACTT
AGGGCTAATGCTCGGAGCATTTGCGAGCTATGCGATTGTTGTTGAAATGATTTTCTCTTGGCCGGGTGTGGGTTCTTGGT
TGGTGTCGGGTATTTATCAGCGGGATTATACGGTTATCCAAGGCGGGATTTTAGCCGTGGCCTTGTTGATCATCTTTTTA
AGTATTTTGATTGAAGTGCTGCATACCGTCTTCAATCCCTTGAGCAGAAAAGATCTTTATGCCTCCAATTAA

Upstream 100 bases:

>100_bases
GAGTCGCTCTCTCCCGAAGCAATATCCATGATATGCAGTTGACCCCCTTTGGTGGCATCTCATTTGCCCGTACTAGTCAA
GCTGAGCAGGAGACACACTG

Downstream 100 bases:

>100_bases
AATTTATCAGGAAGATCAAATCGCCTCGCCGATGATGCGGGTCTGGCAGAATTTTTCGGCAAACCCCTTTGCCTTAGCGG
GTTTGTGGACCATTGCTTTT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MFRYLLRRLNLFLATSLVMVGVLFYATGLFPVERTFALTGIHAPSESQLVQIEQDYKLDSNKAMQFIAYLQQRLSGNLGV
SVTSHQSVAEELSSVLPASFELAVMAAVIAIGLGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQLNLLYEIKPVTGFMLVDILLSDSEYRISAFKDALLHIVLPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTNTIILRHALPNALIPVLKHLGLMLGAFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYASN

Sequences:

>Translated_343_residues
MFRYLLRRLNLFLATSLVMVGVLFYATGLFPVERTFALTGIHAPSESQLVQIEQDYKLDSNKAMQFIAYLQQRLSGNLGV
SVTSHQSVAEELSSVLPASFELAVMAAVIAIGLGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQLNLLYEIKPVTGFMLVDILLSDSEYRISAFKDALLHIVLPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTNTIILRHALPNALIPVLKHLGLMLGAFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYASN
>Mature_343_residues
MFRYLLRRLNLFLATSLVMVGVLFYATGLFPVERTFALTGIHAPSESQLVQIEQDYKLDSNKAMQFIAYLQQRLSGNLGV
SVTSHQSVAEELSSVLPASFELAVMAAVIAIGLGVPLGVLASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDL
GWLPISGQLNLLYEIKPVTGFMLVDILLSDSEYRISAFKDALLHIVLPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
EARGMHTNTIILRHALPNALIPVLKHLGLMLGAFASYAIVVEMIFSWPGVGSWLVSGIYQRDYTVIQGGILAVALLIIFL
SILIEVLHTVFNPLSRKDLYASN

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=43.3962264150943, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=35.9882005899705, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787761, Length=296, Percent_Identity=37.5, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=29.3768545994065, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=28.4457478005865, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787497, Length=337, Percent_Identity=29.080118694362, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788504, Length=314, Percent_Identity=21.0191082802548, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37732; Mature: 37732

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRYLLRRLNLFLATSLVMVGVLFYATGLFPVERTFALTGIHAPSESQLVQIEQDYKLDS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCCEEEECCCCCCCH
NKAMQFIAYLQQRLSGNLGVSVTSHQSVAEELSSVLPASFELAVMAAVIAIGLGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQLNLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDILLSDSEYRISAFKDALLHIVLPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTNTIILRHALPNALIPVLKHLGLMLGAFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYASN
CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFRYLLRRLNLFLATSLVMVGVLFYATGLFPVERTFALTGIHAPSESQLVQIEQDYKLDS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCCEEEECCCCCCCH
NKAMQFIAYLQQRLSGNLGVSVTSHQSVAEELSSVLPASFELAVMAAVIAIGLGVPLGVL
HHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
ASQSQHKLTQNTIMAITLTGYSVPVFWLGLYLSLWFGVDLGWLPISGQLNLLYEIKPVTG
CCCHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEECCHHH
FMLVDILLSDSEYRISAFKDALLHIVLPATTLAVLPFTVVVRSTRSAMMNVMNQTFIRAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARGMHTNTIILRHALPNALIPVLKHLGLMLGAFASYAIVVEMIFSWPGVGSWLVSGIYQ
HHCCCCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RDYTVIQGGILAVALLIIFLSILIEVLHTVFNPLSRKDLYASN
CCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]