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The map label for this gene is dppA [H]

Identifier: 117921091

GI number: 117921091

Start: 3163251

End: 3164876

Strand: Direct

Name: dppA [H]

Synonym: Shewana3_2650

Alternate gene names: 117921091

Gene position: 3163251-3164876 (Clockwise)

Preceding gene: 117921090

Following gene: 117921092

Centisome position: 63.62

GC content: 49.57

Gene sequence:

>1626_bases
ATGAGTGTGCTAATAAGACGCCTGTGCCTATCAACTGCAGTTTTCTGCATGAGTGGGTTGTTGGTTGCATGTGGCCCCCA
ACGACTCCCTTCTGGTTTGGTCTATTGTTCCGAAGGGAATCCCGAGTCTTTTAATCCGCAGTTGGTGACCTCAGGCACCA
CTATCGACGCGACCTCACACCAAATTTATAGCCGCTTAGTGGACTATGATGCGCTCTCAGGCCAGCTCGTGCCAGCGCTG
GCCACCAGTTGGGCCGAGAGCGACGATGGCTTAAGTTACCGTTTCACCCTCAGGGAAAATGTTAAGTTTCAACATTCATC
CCGTTTTACCCCGAGTCGCGATTTTAATGCCGACGATGTGCTGTTTTCCTTCAATCGAATTATCGACAAGCATCACCCTT
ACCATGGCGTATCACGTACCGGTTATCCCTTTTTCCAAAGTATTGGCTTTTCAGAACAAGTTAAAAGTGTTGAAAAAATT
AATGACCACGAGGTGATCTTTCGCCTAGCGCGCAAAGATGCGTCGTTTTTATCGAATCTCGCCACCGACTTTGCAGTTAT
CCTCTCAAGCGAATATGCCGATCAGCAACTGGCATTGGGGCACCCTGAAAATCTCGATCATTTCGCCATTGGTACTGGGC
CTTTTACCTTAGTGCACTACGCTAAAAACGAATATATTCGCTATCGCCGCAATCCCGACTTTTGGGGAGAGCCCGCCAAA
GTCGATATGCTGGTCTACGATATCACCCCCAAAAGCACGGTGAGACTGGCCAAACTTATCGCCGGTGACTGCAGCGTATC
CGCCCTGCCCAAGGCGGGGGAACTACCCGTTATCAAACAACATGAACAGCTGAACATTGAGTCTCAACCCGGTCTTAACG
TCGCCTTTTGGGCCTTTAATACACAAAAGCCTCCTTTAGATGATGTACGCGTGCGCCGTGCCCTCGCCTATGCCGTAGAT
AAGCAAAATATCTTACGTGCCGTGTATCAAAACACCGCCATAGAAGCCATAGGTGTGCTGCCGCCAGCGTCTTGGGCCTA
CGACAGCAATAAAAAACTGTTAGATTACAATCCGCAAAAAGCACGGGATTTGTTAAAAGAAGCGGGAATCAAACATCTCA
GCATCGATATCTGGGCCATGCCCGTCGCCCGCGCCTACAACCCTAACGCGTTAAAAACCGCCGAGTTAATTCAATCTGAT
CTGGCCAATATCGGTGTTAAGGTCAATATTATCAGTTACGATTGGAGCGTCTTTAGCCAAAGATTGAGCCGAGATGAATA
TGACTCAGTCCTCATCGGCTGGAACGCCGATAACAGTGACCCCGATAACTTTTTCACTCCACTGCTGAGTTGCTCGGCGA
TGCAATCAAACAACAATCGCTCTCGCTGGTGCAATAAAGAGTTTGATGCCATTCTAGACAGAGCGAGGGAAGTCTCGACT
CAGGCCGAGCGCAAGGAGATTTACCAGGAGGCCGAAGCCTTCTTAGCTGAGCAAGTGCCAATGTTGAGTCTGGCCCATGC
CAAGCGAGTCGCTCTCTCCCGAAGCAATATCCATGATATGCAGTTGACCCCCTTTGGTGGCATCTCATTTGCCCGTACTA
GTCAAGCTGAGCAGGAGACACACTGA

Upstream 100 bases:

>100_bases
GAAAAAGTACAATTTGCTCGATAAAGCATAAGCAGATTGCCCACGGGCGAGATGCACTGCTAAAATAGCCGTTCATAGTC
GATAAAATAATGATTTATAA

Downstream 100 bases:

>100_bases
TGTTCAGATACCTGTTACGGCGCCTCAACCTGTTTCTTGCCACTTCGCTCGTGATGGTCGGCGTATTGTTTTATGCAACA
GGGTTATTTCCTGTTGAACG

Product: acetate kinase

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSVLIRRLCLSTAVFCMSGLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDALSGQLVPAL
ATSWAESDDGLSYRFTLRENVKFQHSSRFTPSRDFNADDVLFSFNRIIDKHHPYHGVSRTGYPFFQSIGFSEQVKSVEKI
NDHEVIFRLARKDASFLSNLATDFAVILSSEYADQQLALGHPENLDHFAIGTGPFTLVHYAKNEYIRYRRNPDFWGEPAK
VDMLVYDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEQLNIESQPGLNVAFWAFNTQKPPLDDVRVRRALAYAVD
KQNILRAVYQNTAIEAIGVLPPASWAYDSNKKLLDYNPQKARDLLKEAGIKHLSIDIWAMPVARAYNPNALKTAELIQSD
LANIGVKVNIISYDWSVFSQRLSRDEYDSVLIGWNADNSDPDNFFTPLLSCSAMQSNNNRSRWCNKEFDAILDRAREVST
QAERKEIYQEAEAFLAEQVPMLSLAHAKRVALSRSNIHDMQLTPFGGISFARTSQAEQETH

Sequences:

>Translated_541_residues
MSVLIRRLCLSTAVFCMSGLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDALSGQLVPAL
ATSWAESDDGLSYRFTLRENVKFQHSSRFTPSRDFNADDVLFSFNRIIDKHHPYHGVSRTGYPFFQSIGFSEQVKSVEKI
NDHEVIFRLARKDASFLSNLATDFAVILSSEYADQQLALGHPENLDHFAIGTGPFTLVHYAKNEYIRYRRNPDFWGEPAK
VDMLVYDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEQLNIESQPGLNVAFWAFNTQKPPLDDVRVRRALAYAVD
KQNILRAVYQNTAIEAIGVLPPASWAYDSNKKLLDYNPQKARDLLKEAGIKHLSIDIWAMPVARAYNPNALKTAELIQSD
LANIGVKVNIISYDWSVFSQRLSRDEYDSVLIGWNADNSDPDNFFTPLLSCSAMQSNNNRSRWCNKEFDAILDRAREVST
QAERKEIYQEAEAFLAEQVPMLSLAHAKRVALSRSNIHDMQLTPFGGISFARTSQAEQETH
>Mature_540_residues
SVLIRRLCLSTAVFCMSGLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSHQIYSRLVDYDALSGQLVPALA
TSWAESDDGLSYRFTLRENVKFQHSSRFTPSRDFNADDVLFSFNRIIDKHHPYHGVSRTGYPFFQSIGFSEQVKSVEKIN
DHEVIFRLARKDASFLSNLATDFAVILSSEYADQQLALGHPENLDHFAIGTGPFTLVHYAKNEYIRYRRNPDFWGEPAKV
DMLVYDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEQLNIESQPGLNVAFWAFNTQKPPLDDVRVRRALAYAVDK
QNILRAVYQNTAIEAIGVLPPASWAYDSNKKLLDYNPQKARDLLKEAGIKHLSIDIWAMPVARAYNPNALKTAELIQSDL
ANIGVKVNIISYDWSVFSQRLSRDEYDSVLIGWNADNSDPDNFFTPLLSCSAMQSNNNRSRWCNKEFDAILDRAREVSTQ
AERKEIYQEAEAFLAEQVPMLSLAHAKRVALSRSNIHDMQLTPFGGISFARTSQAEQETH

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=535, Percent_Identity=42.6168224299065, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787551, Length=509, Percent_Identity=43.0255402750491, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787052, Length=491, Percent_Identity=25.050916496945, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787762, Length=470, Percent_Identity=25.9574468085106, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789887, Length=549, Percent_Identity=23.8615664845173, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789397, Length=559, Percent_Identity=23.9713774597496, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787495, Length=553, Percent_Identity=24.4122965641953, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081878, Length=524, Percent_Identity=23.2824427480916, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60739; Mature: 60608

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIRRLCLSTAVFCMSGLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSH
CHHHHHHHHHHHHHHHHHCHHEECCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QIYSRLVDYDALSGQLVPALATSWAESDDGLSYRFTLRENVKFQHSSRFTPSRDFNADDV
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCHHH
LFSFNRIIDKHHPYHGVSRTGYPFFQSIGFSEQVKSVEKINDHEVIFRLARKDASFLSNL
HHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ATDFAVILSSEYADQQLALGHPENLDHFAIGTGPFTLVHYAKNEYIRYRRNPDFWGEPAK
HHHHHHHHHCCCCCCCEECCCCCCCCEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCE
VDMLVYDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEQLNIESQPGLNVAFWAFN
EEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEC
TQKPPLDDVRVRRALAYAVDKQNILRAVYQNTAIEAIGVLPPASWAYDSNKKLLDYNPQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCEECCCHHH
ARDLLKEAGIKHLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIISYDWSVFSQ
HHHHHHHCCCCEEEEEEEEECHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEECHHHHHH
RLSRDEYDSVLIGWNADNSDPDNFFTPLLSCSAMQSNNNRSRWCNKEFDAILDRAREVST
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHH
QAERKEIYQEAEAFLAEQVPMLSLAHAKRVALSRSNIHDMQLTPFGGISFARTSQAEQET
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCCHHHCC
H
C
>Mature Secondary Structure 
SVLIRRLCLSTAVFCMSGLLVACGPQRLPSGLVYCSEGNPESFNPQLVTSGTTIDATSH
HHHHHHHHHHHHHHHHHCHHEECCCCCCCCCEEEECCCCCCCCCCEEEECCCEECCHHH
QIYSRLVDYDALSGQLVPALATSWAESDDGLSYRFTLRENVKFQHSSRFTPSRDFNADDV
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEEEECCCEECCCCCCCCCCCCCCHHH
LFSFNRIIDKHHPYHGVSRTGYPFFQSIGFSEQVKSVEKINDHEVIFRLARKDASFLSNL
HHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ATDFAVILSSEYADQQLALGHPENLDHFAIGTGPFTLVHYAKNEYIRYRRNPDFWGEPAK
HHHHHHHHHCCCCCCCEECCCCCCCCEEEECCCCEEEEEECCCCEEEECCCCCCCCCCCE
VDMLVYDITPKSTVRLAKLIAGDCSVSALPKAGELPVIKQHEQLNIESQPGLNVAFWAFN
EEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEC
TQKPPLDDVRVRRALAYAVDKQNILRAVYQNTAIEAIGVLPPASWAYDSNKKLLDYNPQK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCCCEECCCHHH
ARDLLKEAGIKHLSIDIWAMPVARAYNPNALKTAELIQSDLANIGVKVNIISYDWSVFSQ
HHHHHHHCCCCEEEEEEEEECHHHCCCCCHHHHHHHHHHHHHHCCEEEEEEEECHHHHHH
RLSRDEYDSVLIGWNADNSDPDNFFTPLLSCSAMQSNNNRSRWCNKEFDAILDRAREVST
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHH
QAERKEIYQEAEAFLAEQVPMLSLAHAKRVALSRSNIHDMQLTPFGGISFARTSQAEQET
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCCHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]