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The map label for this gene is 117921075

Identifier: 117921075

GI number: 117921075

Start: 3143097

End: 3143999

Strand: Direct

Name: 117921075

Synonym: Shewana3_2634

Alternate gene names: NA

Gene position: 3143097-3143999 (Clockwise)

Preceding gene: 117921074

Following gene: 117921076

Centisome position: 63.21

GC content: 48.95

Gene sequence:

>903_bases
ATGATCCCATTGGTTCATCACGCCAGCTATTCCAAGCTGGCGTTACCCTCCCACCACCGCTTTCCCACGACCAAATACGC
GCGTCTTTACCAATATCTGCTCGATAATCAACTGGCTGTACCGGCTCAATTTCATACTCCCTCACCCATGACGGCTGAAG
ATGTAATGCAGGTGCATCAGCAAGATTATGTCGAACAATTTATCCAAGGCAGATTAGCCTGTGCGGCCTTAAGACGCATC
GGCTTTCCATGGAGTGAAGCCTTGGTTGAGCGCACCTTGCACTCGGTATCGGGGACGAGTTTGACCGCAAGCTTGGCGCT
ACAAGCGGGTATCGCCCTTCACTTAACTGGCGGTTATCACCATGCTCATTATGACTTTGGCAGTGGTTACTGTATTTTCA
ATGATTTAATTATTGCCGCTCGCAAACTGATGGCCGAGCAACAGCTACATAAAGTGCTGATTTTTGATTGTGATGTGCAC
CAAGGCGATGGCACCGCCACCCTTAGCCACAGGCATCAAGGCATTATCAGTTGCTCCATCCACGGCAAAGAGAATTTCCC
GAGCCGCAAACAGCAGTCACACTATGATATTGAATTGACTAAGGGTTCGGATGATAGTGCCTATCAGGAAACCGTCGAGC
AGACTCTCGAGCTGCTGATTCGCCTCCATCAACCGGATCTCATCCTGTATGACGCTGGCGTCGATATCCACCAAGATGAC
GACTTAGGGCACCTAATGATCAGCAAGCAGGGATTGTATCAACGTGATTTAACCGTGTTATCTATGGCAAAAGCAGCAAA
TATTCCTGTTGCAGCGGTAATTGGCGGCGGCTACAGCCGAGACGAACTACAATTAAGCCAAAGACATAGCCAACTTTTTA
TTGCAGCCAACCATTTGTGGTAG

Upstream 100 bases:

>100_bases
GGGCGAATCCACAGCAAATGCTGCAATACTGGTGGTTACAGGCCGATGAGAAAACACGTAAAGAATTTATGAGCTGGGCG
ATTTCTCAGCTCTAATCAAG

Downstream 100 bases:

>100_bases
CAAACTCAATAAAAATCATCATGGAGCACAGCGATGCAACTCGAAATCCGTAACTATTACGAAGTTCTCTTAATGGAAAT
GTTATCCGATGAAGGCCTGA

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIPLVHHASYSKLALPSHHRFPTTKYARLYQYLLDNQLAVPAQFHTPSPMTAEDVMQVHQQDYVEQFIQGRLACAALRRI
GFPWSEALVERTLHSVSGTSLTASLALQAGIALHLTGGYHHAHYDFGSGYCIFNDLIIAARKLMAEQQLHKVLIFDCDVH
QGDGTATLSHRHQGIISCSIHGKENFPSRKQQSHYDIELTKGSDDSAYQETVEQTLELLIRLHQPDLILYDAGVDIHQDD
DLGHLMISKQGLYQRDLTVLSMAKAANIPVAAVIGGGYSRDELQLSQRHSQLFIAANHLW

Sequences:

>Translated_300_residues
MIPLVHHASYSKLALPSHHRFPTTKYARLYQYLLDNQLAVPAQFHTPSPMTAEDVMQVHQQDYVEQFIQGRLACAALRRI
GFPWSEALVERTLHSVSGTSLTASLALQAGIALHLTGGYHHAHYDFGSGYCIFNDLIIAARKLMAEQQLHKVLIFDCDVH
QGDGTATLSHRHQGIISCSIHGKENFPSRKQQSHYDIELTKGSDDSAYQETVEQTLELLIRLHQPDLILYDAGVDIHQDD
DLGHLMISKQGLYQRDLTVLSMAKAANIPVAAVIGGGYSRDELQLSQRHSQLFIAANHLW
>Mature_300_residues
MIPLVHHASYSKLALPSHHRFPTTKYARLYQYLLDNQLAVPAQFHTPSPMTAEDVMQVHQQDYVEQFIQGRLACAALRRI
GFPWSEALVERTLHSVSGTSLTASLALQAGIALHLTGGYHHAHYDFGSGYCIFNDLIIAARKLMAEQQLHKVLIFDCDVH
QGDGTATLSHRHQGIISCSIHGKENFPSRKQQSHYDIELTKGSDDSAYQETVEQTLELLIRLHQPDLILYDAGVDIHQDD
DLGHLMISKQGLYQRDLTVLSMAKAANIPVAAVIGGGYSRDELQLSQRHSQLFIAANHLW

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=291, Percent_Identity=26.1168384879725, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=27.2058823529412, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI13128860, Length=270, Percent_Identity=25.1851851851852, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI13128862, Length=260, Percent_Identity=25.3846153846154, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI293336691, Length=242, Percent_Identity=23.9669421487603, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193207430, Length=301, Percent_Identity=26.578073089701, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17537347, Length=198, Percent_Identity=36.3636363636364, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206283, Length=176, Percent_Identity=28.4090909090909, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540332, Length=176, Percent_Identity=28.4090909090909, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=28.4090909090909, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561978, Length=257, Percent_Identity=24.5136186770428, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323999, Length=260, Percent_Identity=25.3846153846154, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=256, Percent_Identity=26.5625, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325325, Length=191, Percent_Identity=27.2251308900524, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24649807, Length=290, Percent_Identity=24.8275862068966, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644244, Length=265, Percent_Identity=23.7735849056604, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24657891, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33592; Mature: 33592

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLVHHASYSKLALPSHHRFPTTKYARLYQYLLDNQLAVPAQFHTPSPMTAEDVMQVHQ
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHH
QDYVEQFIQGRLACAALRRIGFPWSEALVERTLHSVSGTSLTASLALQAGIALHLTGGYH
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCEE
HAHYDFGSGYCIFNDLIIAARKLMAEQQLHKVLIFDCDVHQGDGTATLSHRHQGIISCSI
EEEEECCCCEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCCCCCEEEEEE
HGKENFPSRKQQSHYDIELTKGSDDSAYQETVEQTLELLIRLHQPDLILYDAGVDIHQDD
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
DLGHLMISKQGLYQRDLTVLSMAKAANIPVAAVIGGGYSRDELQLSQRHSQLFIAANHLW
CCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MIPLVHHASYSKLALPSHHRFPTTKYARLYQYLLDNQLAVPAQFHTPSPMTAEDVMQVHQ
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHH
QDYVEQFIQGRLACAALRRIGFPWSEALVERTLHSVSGTSLTASLALQAGIALHLTGGYH
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEECCEE
HAHYDFGSGYCIFNDLIIAARKLMAEQQLHKVLIFDCDVHQGDGTATLSHRHQGIISCSI
EEEEECCCCEEHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCCCCCEEEEEE
HGKENFPSRKQQSHYDIELTKGSDDSAYQETVEQTLELLIRLHQPDLILYDAGVDIHQDD
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
DLGHLMISKQGLYQRDLTVLSMAKAANIPVAAVIGGGYSRDELQLSQRHSQLFIAANHLW
CCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]