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The map label for this gene is ahpC [C]

Identifier: 117920982

GI number: 117920982

Start: 3037766

End: 3038371

Strand: Reverse

Name: ahpC [C]

Synonym: Shewana3_2541

Alternate gene names: 117920982

Gene position: 3038371-3037766 (Counterclockwise)

Preceding gene: 117920984

Following gene: 117920980

Centisome position: 61.11

GC content: 47.52

Gene sequence:

>606_bases
ATGAGCGTATTAGTAGGCCGTCCGGCTCCTGATTTTACTGCTGCAGCTGTATTAGGTTCTGGCGAAATCGTAGATAGCTT
TAACTTAACTGCGGCCATCAAAGGTAAGCCAGCGGTTGTATTTTTCTATCCACTTGACTTCACTTTCGTTTGTCCATCAG
AGTTGATCGCTTTCGATCACCGCATGGAAGAGTTCACTAAGCGTGGTGTTGAAGTGATCGGTGTGTCTATCGATTCTCAA
TTCACTCACAACGCATGGCGCAACACCCCTGTAGAAAAAGGTGGTATCGGCCAAGTGAAATACACTTTAGTTGCTGACGT
TAAACACGACATCTGTAAAGCATACGATGTTGAGCACCCAGAAGCTGGCGTGGCTTTCCGTGGTTCATTCCTGATCGACA
AAGAAGGTATGGTACGTCACCAAGTGGTTAACGATCTGCCATTAGGCCGTAACGTTGACGAAATGCTGCGTATGATCGAC
GCTCTGCAATTCCACGAAGAGCACGGTGATGTATGCCCTGCGGGTTGGGAAAAAGGCGACAAAGGTATGAACGCAAGCAC
TGAAGGTGTTGCGGCTTACTTAGCAGAAAACGCAAGCTCTCTGTAA

Upstream 100 bases:

>100_bases
TTGGTAAACTCCCTCAAAGACACTCGCGCAAATCAGCGCAAGCGTGTTTAAGGGATGTTTTACTTTAATAGTTAGTTCAA
CTCATAGATGGAGATATAAA

Downstream 100 bases:

>100_bases
TTTGCGGATTTTCGCGTAATAATAAAGCTGCCCTAGGGCAGCTTTTTTATTGGACGGTCGATAAGCATTAACGCCTATTC
CTCACCATCTGCATCCTCTG

Product: alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSVLVGRPAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FTHNAWRNTPVEKGGIGQVKYTLVADVKHDICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLAENASSL

Sequences:

>Translated_201_residues
MSVLVGRPAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQ
FTHNAWRNTPVEKGGIGQVKYTLVADVKHDICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMID
ALQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLAENASSL
>Mature_200_residues
SVLVGRPAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDHRMEEFTKRGVEVIGVSIDSQF
THNAWRNTPVEKGGIGQVKYTLVADVKHDICKAYDVEHPEAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDA
LQFHEEHGDVCPAGWEKGDKGMNASTEGVAAYLAENASSL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=48.9690721649485, Blast_Score=199, Evalue=1e-51,
Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=47.6683937823834, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=47.6683937823834, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=47.6683937823834, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI5453549, Length=190, Percent_Identity=46.3157894736842, Blast_Score=182, Evalue=2e-46,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=43.75, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=44.1489361702128, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI33188454, Length=83, Percent_Identity=59.0361445783133, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=28.643216080402, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786822, Length=158, Percent_Identity=36.7088607594937, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=45.360824742268, Blast_Score=181, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=45.360824742268, Blast_Score=181, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17554494, Length=180, Percent_Identity=46.6666666666667, Blast_Score=171, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI25153706, Length=186, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323613, Length=194, Percent_Identity=40.2061855670103, Blast_Score=157, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6320661, Length=179, Percent_Identity=39.6648044692737, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319407, Length=184, Percent_Identity=29.3478260869565, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=48.4536082474227, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=48.4536082474227, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=48.5875706214689, Blast_Score=182, Evalue=9e-47,
Organism=Drosophila melanogaster, GI17157991, Length=188, Percent_Identity=46.2765957446808, Blast_Score=176, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24641739, Length=188, Percent_Identity=46.2765957446808, Blast_Score=176, Evalue=7e-45,
Organism=Drosophila melanogaster, GI21357347, Length=190, Percent_Identity=43.1578947368421, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24581278, Length=185, Percent_Identity=30.8108108108108, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17975518, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24652434, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24652436, Length=155, Percent_Identity=32.9032258064516, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21929; Mature: 21798

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVGRPAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDH
CCEECCCCCCCHHHEEEECCCCEEECCCEEEEECCCCEEEEEECCCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFTHNAWRNTPVEKGGIGQVKYTLVADVKHDICKAYDVEHP
HHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGDVCPAGWEKGD
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KGMNASTEGVAAYLAENASSL
CCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLVGRPAPDFTAAAVLGSGEIVDSFNLTAAIKGKPAVVFFYPLDFTFVCPSELIAFDH
CEECCCCCCCHHHEEEECCCCEEECCCEEEEECCCCEEEEEECCCEEEECHHHHHHHHH
RMEEFTKRGVEVIGVSIDSQFTHNAWRNTPVEKGGIGQVKYTLVADVKHDICKAYDVEHP
HHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCCC
EAGVAFRGSFLIDKEGMVRHQVVNDLPLGRNVDEMLRMIDALQFHEEHGDVCPAGWEKGD
CCCEEEECEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
KGMNASTEGVAAYLAENASSL
CCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]