Click here to switch to the map view.

The map label for this gene is dcp [H]

Identifier: 117920935

GI number: 117920935

Start: 2982552

End: 2984780

Strand: Direct

Name: dcp [H]

Synonym: Shewana3_2492

Alternate gene names: 117920935

Gene position: 2982552-2984780 (Clockwise)

Preceding gene: 117920930

Following gene: 117920944

Centisome position: 59.98

GC content: 49.71

Gene sequence:

>2229_bases
ATGAAGGGACTTAGCCTAAAATCACAGGCCCTTAACGCGCGCACACTCAAACCACACGCGATTAAACTGACCTTTAGCGC
CATCACGCTCGCCCTCGCCTTAAGTGGCTGTAGTGCACAGCACAGCGATGCTGCGGCGCAGGCGACAGTCGCACCGAATG
CGATGTCGGCGCAAATCATCAGCCAAAATACCAGCAACCCATTCTTTAAACCCTATGATACATTTATGGAAATTCCGGCC
TTCGACAAGATTAAGCCAGAGCATTTCCTCCCTGCATTTAAGGCGGGTATCGCCCAGCAACACGAAGAAATTCAAGCGAT
TGTCGATAGCAAAGACAAGCCTACCTTTGCCAATACCATCGAAGCGATGGAGTTTTCGGGCGATCTCGTCACCCGCGTAT
CCAACGTTTTCTTTAACTTAACTGGCGCTGATACTACTCCTGAGCTGCAAGCGATTTCTAAGGAAGTCTCGCCGATGTTA
TCGTCTGCCGAAGACGATATCTTATTGAACGATAAACTGTTTCAACGTGTTAAAGCCGTTTACGACAGCAAAGGCAGCCT
AAAGCTCAACACGGCGCAGGCCAAATTACTCGAAGACACCTACAAGTCGTTCACCCGTGGCGGTGCTAACCTCAGCGAGC
AGGATAAAACCAAGCTGCGCGCCCTGAATGAAGAAATCGGCAAGCTTAACTTAGCCTTTGGTGACAATCTGTTAGCCGAA
ACCAATGCCTTCGAGCTGGTGATTGATAAGCAAGCTGACCTGTCTGGTTTACCCGCCGATGTGATTGCAACTGCCGCCGA
AACCGCGAAAAAGCGTGGCCATGAAGGCAAATGGGTATTTACCACCTCACGCCCATCTATCACGCCGTTTTTAACCTATG
CCGATAATCGCGAGTTACGCGAAAAGCTCTATAAGGGGTATATCGAACGCGGTAACAATAATAATGCCAATGATAACAAA
GTCATTCTAGCAAAAATTGCCGCGCTGCGTGCCGAACGTGCACAGCTCATGGGCTATAAAACCCATGCGGATTTCGTGTT
AGAAGAGCGCACCGCCAAGACGCCTGAAAATGTCTATGGCTTACTCAATAAAGTTTGGCCAGCAGCCCTTGCCCAAGCCA
AGGCTGAAGTTGCGGATATGCAGGCGTTAATCGACAGCCAAGGCGGCAAGTTTAAGCTGCAAGCTTGGGATTGGGATTAC
TATGCCGATAAAATCCGTGTCGCGAAGTACAGCTTTAACGAGCAGCAAACTCGCCCTTACTTCTCCCTCGACAGCACCCT
AAAAGGCGTGTTCTATACGGCCAATCGCCTCTATGGCTTAACCTTTAAAGAACGTACCGACTTACCCAAATACAACCCAG
AAGTACGTACTTGGGAAGTGTACGATAAAGACGGCAAGCTCATGGCCATCTTTATGGGCGACTATTTTACCCGTGATAGC
AAACGCGGCGGCGCTTGGATGAACTCGTTCCGCAAGCAATACCATATGAACGGTGTCGATTCAAAACCCATTATTGTCAA
CGTGTTGAACTACCCTCGTCCTGCGGGTAATGAGCCTGCGTTGCTCACCTTCGATGAAGCCAGCACCCTGTTCCATGAGT
TTGGCCATGCGCTGCACGGCATGTTATCCAATGTCGAATATCGCTCTCAAGGCGGAACGGCAGTACCTCGCGACTATGTA
GAGTTCCCTTCACAGGTCAACGAAAACTGGATGACTCAGCCTGAAGTGCTCGCGCAATTTGCGAAGCACTACAAAACTGG
TGAAGTGATCCCGCAGGAACTGGTGAAAAAAATCCAAGCCGCCAGCAAATTCAACCAAGGCTTTGCGACCGTTGAATATA
TGGCCGCCACTAAGCTCGATTTAGATTGGCACACCCTAACCGATACCACGCCTAAGGATGCCGCCAAGTTTGAGGCCGAC
TCCTTAGCCGCCATGGGATTGATTAATGAGATCAGCCCACGTTACCGCAGCACTTACTTCTCGCATATCTTCGCGGGCGG
TTATTCAGCCGGTTACTACAGCTACCTCTGGTCAGATATTTTAGGTGCCGATGCCTTTGAAGCCTTTAAAGAAAATGGCA
TTTTCGATAAAGCGACGGCCGATGCCTTCCGTAACAACATCTTATCTAAAGGTGGCAGTGACGACCCTATGCTGATGTAT
AAAAACTTCCGTGGTAAAGAAGCTGGCATTGAGCCGCTGCTGCGTAGCCGTGGTCTGTTAGCGGAGTAA

Upstream 100 bases:

>100_bases
CCTTAGTCGGATACATGCTAAACAGTCACCTTAAAATAACATTAATGGTCTGCAGTACCATTAATCCAACAGAATAATAA
TCACCTAACGGGGAATTGAC

Downstream 100 bases:

>100_bases
TCGCATCCCTATGGGGAAAAGCGAACAGATAAAAATGGGGAGCTAAGCTCCCCATTTTATTGCGCGTAAACGCACTCACC
GCACATAAAACCACTGCTTA

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 742; Mature: 742

Protein sequence:

>742_residues
MKGLSLKSQALNARTLKPHAIKLTFSAITLALALSGCSAQHSDAAAQATVAPNAMSAQIISQNTSNPFFKPYDTFMEIPA
FDKIKPEHFLPAFKAGIAQQHEEIQAIVDSKDKPTFANTIEAMEFSGDLVTRVSNVFFNLTGADTTPELQAISKEVSPML
SSAEDDILLNDKLFQRVKAVYDSKGSLKLNTAQAKLLEDTYKSFTRGGANLSEQDKTKLRALNEEIGKLNLAFGDNLLAE
TNAFELVIDKQADLSGLPADVIATAAETAKKRGHEGKWVFTTSRPSITPFLTYADNRELREKLYKGYIERGNNNNANDNK
VILAKIAALRAERAQLMGYKTHADFVLEERTAKTPENVYGLLNKVWPAALAQAKAEVADMQALIDSQGGKFKLQAWDWDY
YADKIRVAKYSFNEQQTRPYFSLDSTLKGVFYTANRLYGLTFKERTDLPKYNPEVRTWEVYDKDGKLMAIFMGDYFTRDS
KRGGAWMNSFRKQYHMNGVDSKPIIVNVLNYPRPAGNEPALLTFDEASTLFHEFGHALHGMLSNVEYRSQGGTAVPRDYV
EFPSQVNENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTLTDTTPKDAAKFEAD
SLAAMGLINEISPRYRSTYFSHIFAGGYSAGYYSYLWSDILGADAFEAFKENGIFDKATADAFRNNILSKGGSDDPMLMY
KNFRGKEAGIEPLLRSRGLLAE

Sequences:

>Translated_742_residues
MKGLSLKSQALNARTLKPHAIKLTFSAITLALALSGCSAQHSDAAAQATVAPNAMSAQIISQNTSNPFFKPYDTFMEIPA
FDKIKPEHFLPAFKAGIAQQHEEIQAIVDSKDKPTFANTIEAMEFSGDLVTRVSNVFFNLTGADTTPELQAISKEVSPML
SSAEDDILLNDKLFQRVKAVYDSKGSLKLNTAQAKLLEDTYKSFTRGGANLSEQDKTKLRALNEEIGKLNLAFGDNLLAE
TNAFELVIDKQADLSGLPADVIATAAETAKKRGHEGKWVFTTSRPSITPFLTYADNRELREKLYKGYIERGNNNNANDNK
VILAKIAALRAERAQLMGYKTHADFVLEERTAKTPENVYGLLNKVWPAALAQAKAEVADMQALIDSQGGKFKLQAWDWDY
YADKIRVAKYSFNEQQTRPYFSLDSTLKGVFYTANRLYGLTFKERTDLPKYNPEVRTWEVYDKDGKLMAIFMGDYFTRDS
KRGGAWMNSFRKQYHMNGVDSKPIIVNVLNYPRPAGNEPALLTFDEASTLFHEFGHALHGMLSNVEYRSQGGTAVPRDYV
EFPSQVNENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTLTDTTPKDAAKFEAD
SLAAMGLINEISPRYRSTYFSHIFAGGYSAGYYSYLWSDILGADAFEAFKENGIFDKATADAFRNNILSKGGSDDPMLMY
KNFRGKEAGIEPLLRSRGLLAE
>Mature_742_residues
MKGLSLKSQALNARTLKPHAIKLTFSAITLALALSGCSAQHSDAAAQATVAPNAMSAQIISQNTSNPFFKPYDTFMEIPA
FDKIKPEHFLPAFKAGIAQQHEEIQAIVDSKDKPTFANTIEAMEFSGDLVTRVSNVFFNLTGADTTPELQAISKEVSPML
SSAEDDILLNDKLFQRVKAVYDSKGSLKLNTAQAKLLEDTYKSFTRGGANLSEQDKTKLRALNEEIGKLNLAFGDNLLAE
TNAFELVIDKQADLSGLPADVIATAAETAKKRGHEGKWVFTTSRPSITPFLTYADNRELREKLYKGYIERGNNNNANDNK
VILAKIAALRAERAQLMGYKTHADFVLEERTAKTPENVYGLLNKVWPAALAQAKAEVADMQALIDSQGGKFKLQAWDWDY
YADKIRVAKYSFNEQQTRPYFSLDSTLKGVFYTANRLYGLTFKERTDLPKYNPEVRTWEVYDKDGKLMAIFMGDYFTRDS
KRGGAWMNSFRKQYHMNGVDSKPIIVNVLNYPRPAGNEPALLTFDEASTLFHEFGHALHGMLSNVEYRSQGGTAVPRDYV
EFPSQVNENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQAASKFNQGFATVEYMAATKLDLDWHTLTDTTPKDAAKFEAD
SLAAMGLINEISPRYRSTYFSHIFAGGYSAGYYSYLWSDILGADAFEAFKENGIFDKATADAFRNNILSKGGSDDPMLMY
KNFRGKEAGIEPLLRSRGLLAE

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=603, Percent_Identity=28.3582089552239, Blast_Score=264, Evalue=3e-70,
Organism=Homo sapiens, GI14149738, Length=604, Percent_Identity=30.4635761589404, Blast_Score=248, Evalue=2e-65,
Organism=Homo sapiens, GI156105687, Length=451, Percent_Identity=28.3813747228381, Blast_Score=162, Evalue=9e-40,
Organism=Escherichia coli, GI1787819, Length=679, Percent_Identity=42.7098674521355, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1789913, Length=686, Percent_Identity=34.5481049562682, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71999758, Length=587, Percent_Identity=22.8279386712095, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32565901, Length=715, Percent_Identity=20.979020979021, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319793, Length=652, Percent_Identity=26.2269938650307, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322715, Length=467, Percent_Identity=24.1970021413276, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21356111, Length=588, Percent_Identity=21.7687074829932, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129717, Length=451, Percent_Identity=25.9423503325942, Blast_Score=154, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 82794; Mature: 82794

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLSLKSQALNARTLKPHAIKLTFSAITLALALSGCSAQHSDAAAQATVAPNAMSAQII
CCCCCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHEEECCCHHHHHHH
SQNTSNPFFKPYDTFMEIPAFDKIKPEHFLPAFKAGIAQQHEEIQAIVDSKDKPTFANTI
HCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EAMEFSGDLVTRVSNVFFNLTGADTTPELQAISKEVSPMLSSAEDDILLNDKLFQRVKAV
HHHHCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
YDSKGSLKLNTAQAKLLEDTYKSFTRGGANLSEQDKTKLRALNEEIGKLNLAFGDNLLAE
HCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCHHCC
TNAFELVIDKQADLSGLPADVIATAAETAKKRGHEGKWVFTTSRPSITPFLTYADNRELR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHH
EKLYKGYIERGNNNNANDNKVILAKIAALRAERAQLMGYKTHADFVLEERTAKTPENVYG
HHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHH
LLNKVWPAALAQAKAEVADMQALIDSQGGKFKLQAWDWDYYADKIRVAKYSFNEQQTRPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHCEEEEEEECCCCHHCCCE
FSLDSTLKGVFYTANRLYGLTFKERTDLPKYNPEVRTWEVYDKDGKLMAIFMGDYFTRDS
EEHHHHHHHHEEECCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHCCCC
KRGGAWMNSFRKQYHMNGVDSKPIIVNVLNYPRPAGNEPALLTFDEASTLFHEFGHALHG
CCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
MLSNVEYRSQGGTAVPRDYVEFPSQVNENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQA
HHHCCEECCCCCCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
ASKFNQGFATVEYMAATKLDLDWHTLTDTTPKDAAKFEADSLAAMGLINEISPRYRSTYF
HHHHCCCCHHEEEHHHEEECCCCEECCCCCCCHHHHHCHHHHHHHHHHHHCCHHHHHHHH
SHIFAGGYSAGYYSYLWSDILGADAFEAFKENGIFDKATADAFRNNILSKGGSDDPMLMY
HHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
KNFRGKEAGIEPLLRSRGLLAE
ECCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKGLSLKSQALNARTLKPHAIKLTFSAITLALALSGCSAQHSDAAAQATVAPNAMSAQII
CCCCCCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHEEECCCHHHHHHH
SQNTSNPFFKPYDTFMEIPAFDKIKPEHFLPAFKAGIAQQHEEIQAIVDSKDKPTFANTI
HCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EAMEFSGDLVTRVSNVFFNLTGADTTPELQAISKEVSPMLSSAEDDILLNDKLFQRVKAV
HHHHCCCHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
YDSKGSLKLNTAQAKLLEDTYKSFTRGGANLSEQDKTKLRALNEEIGKLNLAFGDNLLAE
HCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCHHCC
TNAFELVIDKQADLSGLPADVIATAAETAKKRGHEGKWVFTTSRPSITPFLTYADNRELR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHH
EKLYKGYIERGNNNNANDNKVILAKIAALRAERAQLMGYKTHADFVLEERTAKTPENVYG
HHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHH
LLNKVWPAALAQAKAEVADMQALIDSQGGKFKLQAWDWDYYADKIRVAKYSFNEQQTRPY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHCEEEEEEECCCCHHCCCE
FSLDSTLKGVFYTANRLYGLTFKERTDLPKYNPEVRTWEVYDKDGKLMAIFMGDYFTRDS
EEHHHHHHHHEEECCCEEEEEEHHCCCCCCCCCCCEEEEEECCCCCEEEEEECCHHCCCC
KRGGAWMNSFRKQYHMNGVDSKPIIVNVLNYPRPAGNEPALLTFDEASTLFHEFGHALHG
CCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHH
MLSNVEYRSQGGTAVPRDYVEFPSQVNENWMTQPEVLAQFAKHYKTGEVIPQELVKKIQA
HHHCCEECCCCCCCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
ASKFNQGFATVEYMAATKLDLDWHTLTDTTPKDAAKFEADSLAAMGLINEISPRYRSTYF
HHHHCCCCHHEEEHHHEEECCCCEECCCCCCCHHHHHCHHHHHHHHHHHHCCHHHHHHHH
SHIFAGGYSAGYYSYLWSDILGADAFEAFKENGIFDKATADAFRNNILSKGGSDDPMLMY
HHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
KNFRGKEAGIEPLLRSRGLLAE
ECCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]