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The map label for this gene is ggt [H]

Identifier: 117920930

GI number: 117920930

Start: 2974016

End: 2975755

Strand: Direct

Name: ggt [H]

Synonym: Shewana3_2487

Alternate gene names: 117920930

Gene position: 2974016-2975755 (Clockwise)

Preceding gene: 117920928

Following gene: 117920935

Centisome position: 59.81

GC content: 51.55

Gene sequence:

>1740_bases
ATGCGCCGCGCAGGAACTTTTAGACCTCTTATTCTCGCCATCGCCATGGCACTGCCTTTGTTGTCTTCGCCCACTCTCCA
TGCCGAAGAACCTTCAATTTTCAGCCAAATGGCCACGGCACAACCCGTATGGGCAAAACATGGTATGGTCGCCAGCCAAG
AAGCGCTGGCCAGCCGCACTGGCATCGAGATTTTGAAGCAAGGCGGTAATGCCGTCGATGCTGCGGTGGCGGTCGCATTC
AGTTTAGCCGTCACGCTACCCCGCGCGGGCAATATTGGTGGCGGTGGCTTTATGCTTGTCCATCTGGCCAAAGAAAACAA
AACCATCGCCATCGATTACCGTGAAATGGCGCCATCAAAGGCGAAAAAAGACATATTCCTCGATGAGAATGGCGATGCGG
TGACTAAATTAAGCCGTGAACATGGTCTGGCAGTCGGCGTCCCCGGCACTGTGATGGGCATGAGTTTAGCCCTTGAAAAA
TATGGCACTATGACCATGGCGCAAGTCACGGCGCCCGCCATCAAAATGGCACAGGAAGGCATTAGCGTGACCCCAGATCT
TGCGGTATCCCTTGCAGGCTTAAAGCGCCGTATGAGCCAATGGCCAAGCACAGCAGCCATCTTCTATAAGGCCGACGGTA
GTGACTACCAAGTGGATGATATTTTAAAACAGCCAGAACTCGCCCACTCCCTGCAACTTATCGCCGAGAAAGGCACTAAA
GGCTTCTACGAAGGTGAAACTGCGGAGAAACTGGTTAAGGCCGTGCAAGATGCTGGCGGCATCATGACCTTAGCGGATTT
AGAACACTATAAGGCCGTTGAGCGTGAACCCGTTCGCGGTCAATACCGTGGATATGACGTAGTTTCTATGCCACCACCAT
CCTCGGGCGGCGTGCACATTATCGAAATGCTCAATGTACTGCAGCAGTTCCCTATCGATCAATTTGGCCATAACACGGCG
CAAACCATTCATGTGATGGCCGAAACCATGAAGCATGCCTACGCCGATCGCAGCGAATACTTAGGCGATCCCGATTTTTA
CAAGGTGCCGGTCAAACAGTTAACCAATAAGGACTACGCCCAAAAAATCGCCAGCCAAATTGCGCTAAACAAAACCACGC
CCAGTACCGAAATCAAACCCGGCAATCTAGCGCCCTATGAGAGTGACCAAACCACGCACTTCTCGGTGGTCGATAAATGG
GGCAATGCGGTGTCTAACACTTACACCTTAAACTTCAGCTACGGCTCGGGTTTAGTCGCCAAAGGTACGGGCATTTTACT
CAATAACGAAATGGATGATTTCTCCGCAAAACCCGGCACACCTAACGGTTATGGCCTAGTGGGTGGCGATGCCAACGCGG
TGGAAGGTAATAAACGTCCTTTAAGTTCAATGAGCCCAACCATAGTGATGAAAGACGGCAAACCCTTCTTAGTTACAGGC
AGCCCTGGCGGTTCACGCATCATTACCACCACGCTGCAAATCATTATGAATGTGATTGATCACGGCTTAAATATTGCCGA
AGCCAGCAATGCTGCGCGGGTACACCACCAATGGCTGCCCGATGAACTGCGAGTCGAAAGCAGCCTAAACCGCGATACCA
TTTCGTTACTCGAAGCTAAAGGCCATAAAGTGAAAGTGCAATCGGCCATGGGCAGCACACAATCTATCATGGTGACAGAC
CAAGGGATTTTTGGTGCCTCAGACCCACGCCATTCGGGTAGCGAAGCCGTCGGTTACTAA

Upstream 100 bases:

>100_bases
TCTTATCCGTTAAACATACTAAGCAAAGATCCAAGGTTGCAATTAAGCCTAATTCTCGGCACATTGCATAGCCAAAATGA
AAATAAATTCAGGATTGAAT

Downstream 100 bases:

>100_bases
TCACTGATTGGCATACTAGCGATATGCATAAAGGCAAGGAAGCCATCGATTGGAGTGATAAGGCTAAGCACAAAGCTGCT
CGATATTGAGTATTCAAGCT

Product: gamma-glutamyltransferase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MRRAGTFRPLILAIAMALPLLSSPTLHAEEPSIFSQMATAQPVWAKHGMVASQEALASRTGIEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHLAKENKTIAIDYREMAPSKAKKDIFLDENGDAVTKLSREHGLAVGVPGTVMGMSLALEK
YGTMTMAQVTAPAIKMAQEGISVTPDLAVSLAGLKRRMSQWPSTAAIFYKADGSDYQVDDILKQPELAHSLQLIAEKGTK
GFYEGETAEKLVKAVQDAGGIMTLADLEHYKAVEREPVRGQYRGYDVVSMPPPSSGGVHIIEMLNVLQQFPIDQFGHNTA
QTIHVMAETMKHAYADRSEYLGDPDFYKVPVKQLTNKDYAQKIASQIALNKTTPSTEIKPGNLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGTPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTD
QGIFGASDPRHSGSEAVGY

Sequences:

>Translated_579_residues
MRRAGTFRPLILAIAMALPLLSSPTLHAEEPSIFSQMATAQPVWAKHGMVASQEALASRTGIEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHLAKENKTIAIDYREMAPSKAKKDIFLDENGDAVTKLSREHGLAVGVPGTVMGMSLALEK
YGTMTMAQVTAPAIKMAQEGISVTPDLAVSLAGLKRRMSQWPSTAAIFYKADGSDYQVDDILKQPELAHSLQLIAEKGTK
GFYEGETAEKLVKAVQDAGGIMTLADLEHYKAVEREPVRGQYRGYDVVSMPPPSSGGVHIIEMLNVLQQFPIDQFGHNTA
QTIHVMAETMKHAYADRSEYLGDPDFYKVPVKQLTNKDYAQKIASQIALNKTTPSTEIKPGNLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGTPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTD
QGIFGASDPRHSGSEAVGY
>Mature_579_residues
MRRAGTFRPLILAIAMALPLLSSPTLHAEEPSIFSQMATAQPVWAKHGMVASQEALASRTGIEILKQGGNAVDAAVAVAF
SLAVTLPRAGNIGGGGFMLVHLAKENKTIAIDYREMAPSKAKKDIFLDENGDAVTKLSREHGLAVGVPGTVMGMSLALEK
YGTMTMAQVTAPAIKMAQEGISVTPDLAVSLAGLKRRMSQWPSTAAIFYKADGSDYQVDDILKQPELAHSLQLIAEKGTK
GFYEGETAEKLVKAVQDAGGIMTLADLEHYKAVEREPVRGQYRGYDVVSMPPPSSGGVHIIEMLNVLQQFPIDQFGHNTA
QTIHVMAETMKHAYADRSEYLGDPDFYKVPVKQLTNKDYAQKIASQIALNKTTPSTEIKPGNLAPYESDQTTHFSVVDKW
GNAVSNTYTLNFSYGSGLVAKGTGILLNNEMDDFSAKPGTPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAKGHKVKVQSAMGSTQSIMVTD
QGIFGASDPRHSGSEAVGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=538, Percent_Identity=32.8996282527881, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI73915090, Length=538, Percent_Identity=32.8996282527881, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI73915096, Length=538, Percent_Identity=32.8996282527881, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI73915094, Length=538, Percent_Identity=32.8996282527881, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI113429324, Length=528, Percent_Identity=32.5757575757576, Blast_Score=236, Evalue=7e-62,
Organism=Homo sapiens, GI113429326, Length=532, Percent_Identity=31.9548872180451, Blast_Score=232, Evalue=8e-61,
Organism=Homo sapiens, GI109148539, Length=555, Percent_Identity=31.7117117117117, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI153266885, Length=547, Percent_Identity=27.0566727605119, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI153266901, Length=548, Percent_Identity=27.1897810218978, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI153266907, Length=547, Percent_Identity=26.1425959780622, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI30581157, Length=229, Percent_Identity=36.6812227074236, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI30581155, Length=229, Percent_Identity=36.6812227074236, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI218505805, Length=228, Percent_Identity=34.2105263157895, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI310124095, Length=228, Percent_Identity=32.8947368421053, Blast_Score=97, Evalue=5e-20,
Organism=Escherichia coli, GI1789856, Length=541, Percent_Identity=60.0739371534196, Blast_Score=646, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72000294, Length=545, Percent_Identity=33.394495412844, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI212646519, Length=546, Percent_Identity=33.3333333333333, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17506189, Length=535, Percent_Identity=31.214953271028, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17542894, Length=556, Percent_Identity=31.4748201438849, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193208245, Length=508, Percent_Identity=30.7086614173228, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI193208247, Length=508, Percent_Identity=30.7086614173228, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17564448, Length=430, Percent_Identity=28.8372093023256, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI72001497, Length=285, Percent_Identity=24.5614035087719, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72001495, Length=285, Percent_Identity=24.5614035087719, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323330, Length=531, Percent_Identity=29.9435028248588, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45551474, Length=547, Percent_Identity=32.9067641681901, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24642670, Length=550, Percent_Identity=32.9090909090909, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642666, Length=550, Percent_Identity=32.9090909090909, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI161077878, Length=550, Percent_Identity=32.9090909090909, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI161077880, Length=550, Percent_Identity=32.9090909090909, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI18859893, Length=512, Percent_Identity=33.203125, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI161077496, Length=544, Percent_Identity=31.4338235294118, Blast_Score=235, Evalue=8e-62,
Organism=Drosophila melanogaster, GI18859741, Length=547, Percent_Identity=28.8848263254113, Blast_Score=194, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62039; Mature: 62039

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAGTFRPLILAIAMALPLLSSPTLHAEEPSIFSQMATAQPVWAKHGMVASQEALASRT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHH
GIEILKQGGNAVDAAVAVAFSLAVTLPRAGNIGGGGFMLVHLAKENKTIAIDYREMAPSK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCC
AKKDIFLDENGDAVTKLSREHGLAVGVPGTVMGMSLALEKYGTMTMAQVTAPAIKMAQEG
CCCCEEEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
ISVTPDLAVSLAGLKRRMSQWPSTAAIFYKADGSDYQVDDILKQPELAHSLQLIAEKGTK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
GFYEGETAEKLVKAVQDAGGIMTLADLEHYKAVEREPVRGQYRGYDVVSMPPPSSGGVHI
CCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHH
IEMLNVLQQFPIDQFGHNTAQTIHVMAETMKHAYADRSEYLGDPDFYKVPVKQLTNKDYA
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCHHHHCCHHHH
QKIASQIALNKTTPSTEIKPGNLAPYESDQTTHFSVVDKWGNAVSNTYTLNFSYGSGLVA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCCEEE
KGTGILLNNEMDDFSAKPGTPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
CCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEC
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAK
CCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHCC
GHKVKVQSAMGSTQSIMVTDQGIFGASDPRHSGSEAVGY
CCEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRAGTFRPLILAIAMALPLLSSPTLHAEEPSIFSQMATAQPVWAKHGMVASQEALASRT
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHH
GIEILKQGGNAVDAAVAVAFSLAVTLPRAGNIGGGGFMLVHLAKENKTIAIDYREMAPSK
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEHHHCCCCC
AKKDIFLDENGDAVTKLSREHGLAVGVPGTVMGMSLALEKYGTMTMAQVTAPAIKMAQEG
CCCCEEEECCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
ISVTPDLAVSLAGLKRRMSQWPSTAAIFYKADGSDYQVDDILKQPELAHSLQLIAEKGTK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCC
GFYEGETAEKLVKAVQDAGGIMTLADLEHYKAVEREPVRGQYRGYDVVSMPPPSSGGVHI
CCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHH
IEMLNVLQQFPIDQFGHNTAQTIHVMAETMKHAYADRSEYLGDPDFYKVPVKQLTNKDYA
HHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEECCHHHHCCHHHH
QKIASQIALNKTTPSTEIKPGNLAPYESDQTTHFSVVDKWGNAVSNTYTLNFSYGSGLVA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEEEEEEECCCCEEE
KGTGILLNNEMDDFSAKPGTPNGYGLVGGDANAVEGNKRPLSSMSPTIVMKDGKPFLVTG
CCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEC
SPGGSRIITTTLQIIMNVIDHGLNIAEASNAARVHHQWLPDELRVESSLNRDTISLLEAK
CCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHCCCHHHHHHHCCCHHHHHHHHCC
GHKVKVQSAMGSTQSIMVTDQGIFGASDPRHSGSEAVGY
CCEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]