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The map label for this gene is cysL [H]

Identifier: 117920873

GI number: 117920873

Start: 2913525

End: 2914391

Strand: Direct

Name: cysL [H]

Synonym: Shewana3_2430

Alternate gene names: 117920873

Gene position: 2913525-2914391 (Clockwise)

Preceding gene: 117920871

Following gene: 117920874

Centisome position: 58.6

GC content: 49.83

Gene sequence:

>867_bases
ATGATAAATCCACAATGGCTCAATACCTTTGCAGTGTTAGTGGAAAAGGGAAACTTTACCCGCACGGCCGAAGCCATAGG
TATCACCCAAGCCGCGGTCAGCCAGCATATCAGTCGCTTAGAGGAAGAGTACGGCACCCTATTTTTGCGCCGTAGCCGCC
AACTCGAAATCACTCCCATTGGTGAGCATTTGTTGAGTTACGTCAACGATATAGACTGCGCCAAGAAGCGATTACAGCAA
AAACTCATTCAAGACGATGCCCATATTGGCGAGATTAGCCTTATCACCCCTGGCAGTATTGGCTTAACCCTCTACCCCTT
GCTTTTACAGCTACAAACGGCGTTTTCGCAGCTAAAAATTCATCATCGTTTTGCCCCCGATAATGAAATCCTCTCCGCCA
TTCTCGCTAATCAACATGAGCTGGGGATGGTGACGTTTAAGCCGTCGGATCCCAGTATTTGCAGCAGCCATTTTACCGAA
GAGCCCCTCGAGTTGGTTGTGCCTGCGGGGCAGAAAATTACCAGTTGGCAAGATTTGCAGCGCCTCGGATTTATCTCCCA
CCCCGATGGCGAAGCCATGGCCACCCGTTTATTGAGCCGCAAATATCCAGGGAGTCCTGGCATCCAAGAGATCCCCTGTA
AAGGTTTTATCAATCAGATAAGCTTAATCTTGGAACCCGTCGCCAAGGGACTCGGCTTTACCGTGATCCCACGTTATGCC
CGTAAGGCCTTTGAACGGCAAGAGGAAATCTATGTGGTTGAGTGTGGCAGCCAAGTCGTGGACACCATTTGGTTGATCCA
CAGAGCCGAGTGGCCTTTGTCCCGCCGAGCACAAACGGCCATCGATTACTTAAAAAGTCAGATTTAA

Upstream 100 bases:

>100_bases
CTGACAGTCCTAACCATGGGTTAACTAGATGAGGACAGACTAAAACGAACGTGCCATAATTAAAAGTATCACCATATTAT
AGGTTCTATAAGATTTCGTT

Downstream 100 bases:

>100_bases
CTTAAACCGACAGGTTGAAATGTCACGGCGAAAGGCGTTAAAGAGGCAAAGTGAATGCCTAGTAATAGAAATCTAGCCAT
TTTAGAACAACATAATTAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: CysJI operon transcriptional activator [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MINPQWLNTFAVLVEKGNFTRTAEAIGITQAAVSQHISRLEEEYGTLFLRRSRQLEITPIGEHLLSYVNDIDCAKKRLQQ
KLIQDDAHIGEISLITPGSIGLTLYPLLLQLQTAFSQLKIHHRFAPDNEILSAILANQHELGMVTFKPSDPSICSSHFTE
EPLELVVPAGQKITSWQDLQRLGFISHPDGEAMATRLLSRKYPGSPGIQEIPCKGFINQISLILEPVAKGLGFTVIPRYA
RKAFERQEEIYVVECGSQVVDTIWLIHRAEWPLSRRAQTAIDYLKSQI

Sequences:

>Translated_288_residues
MINPQWLNTFAVLVEKGNFTRTAEAIGITQAAVSQHISRLEEEYGTLFLRRSRQLEITPIGEHLLSYVNDIDCAKKRLQQ
KLIQDDAHIGEISLITPGSIGLTLYPLLLQLQTAFSQLKIHHRFAPDNEILSAILANQHELGMVTFKPSDPSICSSHFTE
EPLELVVPAGQKITSWQDLQRLGFISHPDGEAMATRLLSRKYPGSPGIQEIPCKGFINQISLILEPVAKGLGFTVIPRYA
RKAFERQEEIYVVECGSQVVDTIWLIHRAEWPLSRRAQTAIDYLKSQI
>Mature_288_residues
MINPQWLNTFAVLVEKGNFTRTAEAIGITQAAVSQHISRLEEEYGTLFLRRSRQLEITPIGEHLLSYVNDIDCAKKRLQQ
KLIQDDAHIGEISLITPGSIGLTLYPLLLQLQTAFSQLKIHHRFAPDNEILSAILANQHELGMVTFKPSDPSICSSHFTE
EPLELVVPAGQKITSWQDLQRLGFISHPDGEAMATRLLSRKYPGSPGIQEIPCKGFINQISLILEPVAKGLGFTVIPRYA
RKAFERQEEIYVVECGSQVVDTIWLIHRAEWPLSRRAQTAIDYLKSQI

Specific function: Transcriptional activator of the cysJI operon which is involved in sulfur assimilation. Also negatively regulates its own transcription [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32435; Mature: 32435

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINPQWLNTFAVLVEKGNFTRTAEAIGITQAAVSQHISRLEEEYGTLFLRRSRQLEITPI
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
GEHLLSYVNDIDCAKKRLQQKLIQDDAHIGEISLITPGSIGLTLYPLLLQLQTAFSQLKI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HHRFAPDNEILSAILANQHELGMVTFKPSDPSICSSHFTEEPLELVVPAGQKITSWQDLQ
HHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCCHHEEECCCCCCCCHHHHH
RLGFISHPDGEAMATRLLSRKYPGSPGIQEIPCKGFINQISLILEPVAKGLGFTVIPRYA
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RKAFERQEEIYVVECGSQVVDTIWLIHRAEWPLSRRAQTAIDYLKSQI
HHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINPQWLNTFAVLVEKGNFTRTAEAIGITQAAVSQHISRLEEEYGTLFLRRSRQLEITPI
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEH
GEHLLSYVNDIDCAKKRLQQKLIQDDAHIGEISLITPGSIGLTLYPLLLQLQTAFSQLKI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
HHRFAPDNEILSAILANQHELGMVTFKPSDPSICSSHFTEEPLELVVPAGQKITSWQDLQ
HHCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCCHHEEECCCCCCCCHHHHH
RLGFISHPDGEAMATRLLSRKYPGSPGIQEIPCKGFINQISLILEPVAKGLGFTVIPRYA
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RKAFERQEEIYVVECGSQVVDTIWLIHRAEWPLSRRAQTAIDYLKSQI
HHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]