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The map label for this gene is fadE [H]

Identifier: 117920766

GI number: 117920766

Start: 2795424

End: 2797871

Strand: Direct

Name: fadE [H]

Synonym: Shewana3_2323

Alternate gene names: 117920766

Gene position: 2795424-2797871 (Clockwise)

Preceding gene: 117920764

Following gene: 117920770

Centisome position: 56.22

GC content: 49.26

Gene sequence:

>2448_bases
GTGACTACCCTACTTTGGATCATCGCCATGATCTTAGTGCTAGGAGCCCTAGCTTACCTTCGGGTATCTTTGCTCACTGC
CACTATTGCAGCCGCTGTTGTGATGACAGCCGGATGGACACTCGATGTTGTCGGCCCTATCTCTTGGATTATCTTCCTGG
TGATCGCGCTGCCCCTCAATATCAGTGCATTTAGACAAAATGTTATCAGTCGCCCACTGATGAAGACCTACCGTGGCATC
ATGCCCGAAATGTCTTCTACCGAAAAAGAAGCGATTGAAGCTGGTACCACTTGGTGGGAAGCCGATCTGTTTGCGGGTAA
CCCAAACTGGAAAAAACTCCACAACTATCCTGTCGCTCGTTTAAGTGCCGATGAGCAAGCCTTCTTAGACGGCCCCGTTG
AAGAAGTGTGCCGCATGGTGAATCAACACCAAGTATCACACCAACTGGCTGATTTGCCTGCTGAAGTATGGCAATACCTG
AAAGATCACGGCTTCTTCGCCATGATCATCAAGAAAAAATACGGCGGTTTAGAGTACTCAGCCTACGCCCAATCACGCGT
ACTGCAAAAGCTTGCAGGTTTAAGCAGTGAACTAGCATCCACTGTAGGTGTACCTAACTCCTTAGGCCCTGGCGAACTGT
TACAACACTATGGTACGCCTGAGCAGCAAAACCATTACCTGCCAAGGTTAGCCAAAGGTTTAGAAGTCCCTTGTTTCGCG
TTAACTAGCCCAGAGGCTGGTAGCGACGCAGGTTCTATCCCTGACTTTGGTATCGTGTGTAAAGGTCAATGGGAAGGCGA
AGAAGTCTTAGGTATGCGCTTAACCTGGAACAAGCGTTATATCACCCTAGCGCCGGTGGCGACGGTATTAGGTCTGGCGT
TTAAACTGCGTGACCCTGATCACCTGTTAGGCGATAAAGAAGAGCTGGGCATTACCTGCGCGCTGATCCCAACTGACGTT
GAAGGCGTTGAAACAGGTCGTCGTCACTTCCCGCTGAACTGTATGTTCCAAAACGGTCCTACTCGCGGTAAAGACGTATT
CGTCCCATTAAGCTTTATCATCGGTGGTCCGAAAATGGCTGGCCAAGGCTGGCGCATGCTGGTTGAGTGTTTATCTGTTG
GCCGTGGTATCACGCTGCCATCAAACTCTGCTGGTGGCGTGAAAACCGCAGCGCTTGCAACAGGTGCGTATGCGCGTATT
CGTCGTCAATTCAAACTGCCGATTGGTAAGTTAGAAGGGATTGAAGAGCCAATGGCACGCATCGGTGGTAACGCTTATTT
GATGGATGCAGTGACCTCATTAACCACCACAGGTATCGACCTAGGTGAAAAACCTTCGGTTATCTCGGCAATCGTGAAAT
ATCACCTGACCGATCGTATGCAGAAGTGCGTTATCGATGCCATGGATATCCACGGTGGTAAAGGTGTGTGCTTAGGCCCT
AACAACTACTTAGGTCGTGGCTATCAAGCGGCTCCGATTGCGATTACCGTTGAAGGTGCAAACATCCTGACACGTTCGAT
GATCATCTATGGTCAAGGTGCAATCCGTTGTCATCCTTATGTATTGGCCGAAATGGAGTCAGCGTTTGATACTGAGTCTG
GCCAAGGTTTAGCCAACTTCGATGCGGCCATCTTCGGTCATATTGGTTTTGCGACCAGTAACTTTGTCCGTAGCTTCTGG
CTAGGTCTGACATCAAGCCGTTTCTCTAACGCGCCATACTCAGACAAAACCAAGCGTTATTATCAACATATGAACCGTTT
CAGTGCCAACTTAGCCCTGCTATCAGATTTGGCCATGGCAACCTTAGGCGGTAACTTAAAGCGTAAAGAGCGTATTTCTG
CCCGCTTAGGCGATCTGTTAAGCCAGTTATACCTCGCTTCTGCAACCTTAAAACGTTACCAAGATGAAGGCCGTCAAACT
GACGATCTACCACTGGTGCAATGGGCGGTTGAAGATGCGCTGTACAAATTACAGGCTTCATTAGACGATTTACTGGATAA
CTTCCCTATGGGTCTGGGCGGCGTGTTACGTGCCATCATGTTCCCATTCGGCCGTCCACTGAAACGTCCAAGCGATGTGT
TAGATCATAAAGTGGCTAAGATCATGCAAACCCCATGTGAAAGCCGTGATCGTTTAGGTAAAGGTCAGTTCTGGACTAAC
TCTGAGCACAATGCTGTGGGTATCCAAGAGCAAACGCTGAAGGATATTTTGGCCGCCGAACCTTTATTCGACAAAGTCTG
TAAGGCCAGCGGTAAGCGTCTACCTTTCATGTGGTTAGATAAAGTTGCCGCCGAAGGTAAAGCCTTAGGCGTATTGAGCG
ACAGCGAAGTACAACTGTTGGAACGTGCCGAAATCGGCCGTATGAAGTCTATCAATGTGGATGACTTTGACCCAGCTGAG
CTGCGCCCAGAAGTCGTCGCAACGACATCACAAGAACGCGCCGCTTAA

Upstream 100 bases:

>100_bases
ATGCGACACAGGTCAGACCACAAACTATAATTGTGATCGCAATCAACAAAACTCGTTATGACCTGTGATTGGCACTCGGT
CATACTTAAGGAGAAATACA

Downstream 100 bases:

>100_bases
TAGCGAAACTGTACTAGTTGAGCTGTACTAACTAAGCTGTACTAAATAAGTCCATCTAAATAAACAAAAAGGCACTACCT
ATGTAGTGCCTTTTTTATTT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIIFLVIALPLNISAFRQNVISRPLMKTYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTESGQGLANFDAAIFGHIGFATSNFVRSFW
LGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYQDEGRQT
DDLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRAIMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEVQLLERAEIGRMKSINVDDFDPAE
LRPEVVATTSQERAA

Sequences:

>Translated_815_residues
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIIFLVIALPLNISAFRQNVISRPLMKTYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTESGQGLANFDAAIFGHIGFATSNFVRSFW
LGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYQDEGRQT
DDLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRAIMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEVQLLERAEIGRMKSINVDDFDPAE
LRPEVVATTSQERAA
>Mature_814_residues
TTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIIFLVIALPLNISAFRQNVISRPLMKTYRGIM
PEMSSTEKEAIEAGTTWWEADLFAGNPNWKKLHNYPVARLSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLK
DHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFAL
TSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPDHLLGDKEELGITCALIPTDVE
GVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIR
RQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGPN
NYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTESGQGLANFDAAIFGHIGFATSNFVRSFWL
GLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYQDEGRQTD
DLPLVQWAVEDALYKLQASLDDLLDNFPMGLGGVLRAIMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTNS
EHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEVQLLERAEIGRMKSINVDDFDPAEL
RPEVVATTSQERAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=553, Percent_Identity=26.5822784810127, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI4557235, Length=406, Percent_Identity=25.1231527093596, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI4557233, Length=418, Percent_Identity=26.555023923445, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI87081702, Length=816, Percent_Identity=65.4411764705882, Blast_Score=1104, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=307, Percent_Identity=25.4071661237785, Blast_Score=73, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=339, Percent_Identity=24.7787610619469, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=269, Percent_Identity=26.0223048327138, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281363737, Length=444, Percent_Identity=24.7747747747748, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=25.706940874036, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355753, Length=323, Percent_Identity=24.1486068111455, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89301; Mature: 89170

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIIFLVIALPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC
ISAFRQNVISRPLMKTYRGIMPEMSSTEKEAIEAGTTWWEADLFAGNPNWKKLHNYPVAR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECEEECCCCCHHHHCCCCCCE
LSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLKDHGFFAMIIKKKYGGLEYS
ECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDKEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMA
HHCCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTESGQGLANF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCCHHH
DAAIFGHIGFATSNFVRSFWLGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYQDEGRQTDDLPLVQWAVEDALYKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGGVLRAIMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEVQLL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCHHHHHH
ERAEIGRMKSINVDDFDPAELRPEVVATTSQERAA
HHHHCCCCCCCCCCCCCHHHCCCHHEEECCHHCCC
>Mature Secondary Structure 
TTLLWIIAMILVLGALAYLRVSLLTATIAAAVVMTAGWTLDVVGPISWIIFLVIALPLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC
ISAFRQNVISRPLMKTYRGIMPEMSSTEKEAIEAGTTWWEADLFAGNPNWKKLHNYPVAR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEECEEECCCCCHHHHCCCCCCE
LSADEQAFLDGPVEEVCRMVNQHQVSHQLADLPAEVWQYLKDHGFFAMIIKKKYGGLEYS
ECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPEQQNHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDFGIVCKGQWEGEEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCH
HLLGDKEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMA
HHCCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDTESGQGLANF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCCHHH
DAAIFGHIGFATSNFVRSFWLGLTSSRFSNAPYSDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYQDEGRQTDDLPLVQWAVEDALYKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGGVLRAIMFPFGRPLKRPSDVLDHKVAKIMQTPCESRDRLGKGQFWTN
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
SEHNAVGIQEQTLKDILAAEPLFDKVCKASGKRLPFMWLDKVAAEGKALGVLSDSEVQLL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEECCHHHHHH
ERAEIGRMKSINVDDFDPAELRPEVVATTSQERAA
HHHHCCCCCCCCCCCCCHHHCCCHHEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]