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The map label for this gene is hscB [H]

Identifier: 117920720

GI number: 117920720

Start: 2740757

End: 2741281

Strand: Reverse

Name: hscB [H]

Synonym: Shewana3_2277

Alternate gene names: 117920720

Gene position: 2741281-2740757 (Counterclockwise)

Preceding gene: 117920721

Following gene: 117920719

Centisome position: 55.13

GC content: 49.14

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAAGTTTTCCCCTGCCTTCGATATTGACACCGCTGTGCTTGCAGAACGCTACCGCGAACT
GCAACGGGCGGTGCATCCCGATAAGTTTGCCAACGATACCGAGCAACAACGCTTATTGTCGGTGCAACGCACTGCGCAAG
TGAATGACGGTTATCAAACCCTAAAAGATCCTATCCGCCGTGCCGAGCATATGCTGTCGCTACGTGGTATCGATTTAAGC
CACGAAACCACCACAGTGAAAGACACTGCATTTTTAATGCAGCAGATGGAATGGCGTGAGGCGTTAGAAGACATTCGCGA
TAGTGCCGATCCCCAAGAAAGCATTGATGAGTTATACGACTCTTTCGCGGCCTACCGGACTAAGTTGACGAAATTGCTCA
CCGCCCAGCTAAGCAGTGGCAGCGAAGATGATGCCTTGTTAGCGGCAGATCAAGTACGCAAGCTTAAATTTATGGCAAAA
TTACACGATGAGCTGACGCGTATCGAAGACGCGCTGCTCGATTAA

Upstream 100 bases:

>100_bases
TAAAGAAGGCCTGAACGAAGGTTTCCAATTTAACAATCCTAACGCAAAAGGTGAGTGCGGTTGCGGTGAGAGTTTCACTG
TTTAATTGCCGAATTGACGC

Downstream 100 bases:

>100_bases
TTTTCCCTATTGCAGTTATTTAGCCGATTCAGACGGGTCTGAGTCGGCGCTACTAAGTTGGATACATATGGCCCTTTTGC
AGATTGCAGAGCCCGGACAA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQTLKDPIRRAEHMLSLRGIDLS
HETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYDSFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAK
LHDELTRIEDALLD

Sequences:

>Translated_174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQTLKDPIRRAEHMLSLRGIDLS
HETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYDSFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAK
LHDELTRIEDALLD
>Mature_174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQTLKDPIRRAEHMLSLRGIDLS
HETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYDSFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAK
LHDELTRIEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=164, Percent_Identity=29.2682926829268, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788876, Length=178, Percent_Identity=41.0112359550562, Blast_Score=128, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321420, Length=117, Percent_Identity=35.042735042735, Blast_Score=61, Evalue=8e-11,
Organism=Drosophila melanogaster, GI161084223, Length=108, Percent_Identity=34.2592592592593, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20132; Mature: 20132

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQT
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIDLSHETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAKLHDELTRIEDALLD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQT
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHH
LKDPIRRAEHMLSLRGIDLSHETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
SFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAKLHDELTRIEDALLD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]