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The map label for this gene is nadA [H]

Identifier: 117920572

GI number: 117920572

Start: 2552678

End: 2553751

Strand: Reverse

Name: nadA [H]

Synonym: Shewana3_2128

Alternate gene names: 117920572

Gene position: 2553751-2552678 (Counterclockwise)

Preceding gene: 117920573

Following gene: 117920571

Centisome position: 51.36

GC content: 49.63

Gene sequence:

>1074_bases
ATGAGCCCCAGCCCATTTGCCCCAACAATCGAAACTATTGATTATCCGTTTCCGCCTAAGCCAATTCCTCTGTCCGATGC
CGAAAAGGCGGACTACAAGGCACGTATCAAGCAGCTGCTGATTGAAAAAGATGCGGTATTGGTTGCCCATTATTATACCG
ACCCTGAAATTCAAGCTCTGGCCGAAGAAACTGGCGGTTGTGTTTCTGACTCACTCGAAATGGCGCGCTTTGGCCGCGAT
CATCCCGCCAAGACGTTAATCGTCGCCGGGGTGAAATTTATGGGTGAAACCGCCAAAATCTTAAGCCCTGAAAAAACCAT
TCTGATGCCGACCTTGGAGGCGACCTGTTCATTGGACTTAGGTTGCCCCATCGATAAATTCAATGCCTTCTGTGATGCGC
ATCCTGATCATACCGTAGTCGTTTATGCCAACACTTCGGCGGCGGTAAAAGCCCGTGCCGATTGGGTGGTCACCTCAAGT
ATTGCCCTTGAAATCGTTGAGCATTTAGACAGCGAAGGCAAAAAAATCATTTGGGGCCCAGACCGTCATTTAGGCAGTTA
TATTGCCAAACAAACGGGCGCCGAGATGTTGATGTGGCAGGGTGACTGTATCGTTCACGATGAGTTTAAGGCCAATGCGC
TGCGAGATTTAAAGCGTGTTTACCCTGACGCGGCGATTCTAGTGCACCCAGAGTCACCCGCGAGTGTGGTTGCGATGGCG
GATGCTGTCGGCTCCACCAGCCAGTTGATTAAAGCTGCGCAAACCATGGCAAATGAGCGTTTTATTGTGGCGACCGATCG
CGGTATTTTCTATAAAATGCAACAAGCGGCGCCGGGTAAAACACTGATTGAAGCGCCTACTGGCGGTAATGGTGCCACCT
GTAAGAGCTGTGCTCACTGTCCTTGGATGGCGATGAATGGCTTAAAGGCGATTGAAGCGTCCTTAAGTGACAGCGACAAA
ACGACTCACGAAATCTTTGTCGATGAAGATTTACGCGTGAAAGCCTTAATCCCGCTTACCCGTATGCTCGATTTCGCTAA
AACACTGAATATGAAAGTGAAAGGCAACGCTTAA

Upstream 100 bases:

>100_bases
GCAATTTAGCGTCCTTTTTTATTCGCAGGCCATAAATGGGTTAATCTTTTGATCCCAATTACGTATAATTCGCGAACGTT
GTTATCCTGATGGATTTGTT

Downstream 100 bases:

>100_bases
TCAAGCGTGCATAACACTCACGAAAAATGAAATCCCTGCCACTTGGCGGGGATTTTTGTATCGGTTCAAATTGATCAGCA
GCTAAGCTGCTAAGTATGTG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSPSPFAPTIETIDYPFPPKPIPLSDAEKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRD
HPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSS
IALEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMA
DAVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEASLSDSDK
TTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA

Sequences:

>Translated_357_residues
MSPSPFAPTIETIDYPFPPKPIPLSDAEKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRD
HPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSS
IALEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMA
DAVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEASLSDSDK
TTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
>Mature_356_residues
SPSPFAPTIETIDYPFPPKPIPLSDAEKADYKARIKQLLIEKDAVLVAHYYTDPEIQALAEETGGCVSDSLEMARFGRDH
PAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPIDKFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSSI
ALEIVEHLDSEGKKIIWGPDRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMAD
AVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHCPWMAMNGLKAIEASLSDSDKT
THEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=340, Percent_Identity=73.8235294117647, Blast_Score=536, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38789; Mature: 38658

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSPFAPTIETIDYPFPPKPIPLSDAEKADYKARIKQLLIEKDAVLVAHYYTDPEIQAL
CCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHH
AEETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDL
HHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEEECC
GCPIDKFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGP
CCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECC
DRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMA
CHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEH
DAVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHC
HHCCCHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCEEEECCCCCCCCCCHHHCCC
PWMAMNGLKAIEASLSDSDKTTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
CHHHHCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure 
SPSPFAPTIETIDYPFPPKPIPLSDAEKADYKARIKQLLIEKDAVLVAHYYTDPEIQAL
CCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHH
AEETGGCVSDSLEMARFGRDHPAKTLIVAGVKFMGETAKILSPEKTILMPTLEATCSLDL
HHHHCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHCCCCCEEEEEECHHHEEECC
GCPIDKFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKKIIWGP
CCCHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHCCCCCEEEECC
DRHLGSYIAKQTGAEMLMWQGDCIVHDEFKANALRDLKRVYPDAAILVHPESPASVVAMA
CHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEH
DAVGSTSQLIKAAQTMANERFIVATDRGIFYKMQQAAPGKTLIEAPTGGNGATCKSCAHC
HHCCCHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCEEEECCCCCCCCCCHHHCCC
PWMAMNGLKAIEASLSDSDKTTHEIFVDEDLRVKALIPLTRMLDFAKTLNMKVKGNA
CHHHHCCHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]